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Flow through pain-sensing molecule helps worms adapt to pain

When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.

2 Sep 2014

American scientists develop another groundbreaking click concept: SuFEx

The coupling of molecular building blocks nearly as easy as “snapping” them together can be realized by means of the “click chemistry” tool kit. American scientists have now introduced another achievement for the click concept in the journal Angewandte Chemie: the sulfur fluoride exchange reaction (SuFEx) can be used to form robust inorganic bridges between carbon centers and opens up a fully unexplored area of chemistry with countless new molecules that could form the basis for new drugs, diagnostics, plastics, “intelligent” materials, and many other products.

2 Sep 2014

Live cell imaging solution launched by QImaging

QImaging™ today launched a new, all-in-one camera package that supports demanding live cell fluorescence imaging requirements. The Live Cell Imaging Package provides researchers with the sensitivity of EMCCD and the versatility of sCMOS camera technologies by combining QImaging’s Rolera™ Thunder EMCCD and optiMOS™ sCMOScameras. Now, researchers can address their unique imaging needs for a broader, more diverse set of scientific applications.

21 Aug 2014

UI scientists discover that CF mucus abnormality is present at birth

Mucus is key to keeping our lungs clean and clear of bacteria, viruses, and other foreign particles that can cause infection and inflammation. When we inhale microbes and dust, they are trapped in the mucus and then swept up and out of the lungs via a process called mucociliary transport.

16 Aug 2014

Study sheds new light on how carbon monoxide could help protect hearts against arrhythmias

A study, funded by the British Heart Foundation and Medical Research Council, has shed new light on how carbon monoxide could be used to protect against life-threatening arrhythmias after a heart attack.

16 Aug 2014

Cerilliant offers nine new stable isotope-labeled internal standards of 2C amines

Sigma-Aldrich Corporation is pleased to announce that the Cerilliant® brand within its Applied Diagnostics and Testing business segment now offers nine new stable isotope-labeled internal standards of 2C amines including deuterium and 13C labeling.

14 Aug 2014

Study identifies novel gene that controls nerve conduction velocity linked with MS

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity.

13 Aug 2014

Researchers create synthetic ion transporter that triggers apoptosis in cancer cells

Researchers from the University of Southampton are part of an international team that has helped to create a molecule that can cause cancer cells to self-destruct by carrying sodium and chloride ions into the cells.

12 Aug 2014

Researchers create synthetic molecule that can cause cancer cells to self-destruct

Researchers from The University of Texas at Austin and five other institutions have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells.

12 Aug 2014

Advion introduces high performance liquid chromatography to complement its CMS

Advion, Inc., a leading systems and consumables developer for the life sciences industry, introduces an affordable high performance liquid chromatography system to complement its line of expression compact mass spectrometers (CMS). Introduced in 2012, the CMS has been met with glowing reviews from the global synthetic organic chemistry market. With hundreds of CMS purchased and installed, this latest introduction offers a complete solution for those needing separation capabilities at an affordable price.

From Advion 7 Aug 2014

Advion releases Direct Analysis Probe for the compact mass spectrometer (CMS) product line

Advion, Inc., a leading systems and consumables developer for the life sciences industry, announces the release of a Direct Analysis Probe for its line of expression compact mass spectrometers (CMS). With hundreds of CMS systems utilized in chemistry laboratories around the world, this latest development creates yet another important tool for chemists that need fast, simple, reliable sample analysis of liquids and solids such as reaction mixtures, food samples, natural products and tablets without the need for sample preparation.

From Advion 7 Aug 2014

UMass Amherst researcher receives grant to uncover molecular mechanisms of skeletal muscle fatigue

Muscle physiologist Edward Debold at the University of Massachusetts Amherst's School of Public Health and Health Sciences recently received a three-year, $198,000 grant from the American Heart Association to support studies to uncover the molecular mechanisms of skeletal muscle fatigue.

7 Aug 2014

Some states boost transparency of insurance rate review amid criticism

Connecticut regulators deny an insurer's proposed rate increase but criticize the state's public hearing process. Meanwhile, Illinois officials give the public online access to rate filings and Florida advocates blame state lawmaker's suspension of rate review for the big premium increases in that state.

7 Aug 2014

First Edition: August 6, 2014

Today's headlines include reports about the Gallup-Healthways Well-Being Index that details how politics play a role in the nation's health care gap between red and blue states.

6 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Study: Spicy capsaicin can reduce risk of colorectal tumors

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin - the active ingredient in chili peppers - produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.

3 Aug 2014

Clinical study aims to validate preventive treatment against tumor metastasis

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer.

25 Jul 2014

Short movie shows development of dressing promotes wound healing

Someone suffers second- or third-degree burns: The wound must immediately be dressed and the dressing is to be changed regularly. A short movie made by the group of Prof. Dr.-Ing. Stephan Barcikowski shows the development of a dressing that promotes wound healing - from the materials research laboratory until the first practical trial (in English).

24 Jul 2014

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

The New York State Department of Health (DOH) has granted Roswell Park Cancer Institute (RPCI) approval to begin genomic testing of cancer patients using its OmniSeq TargetTM advanced molecular diagnostic laboratory test.

21 Jul 2014

Freedom portable driver receives FDA approval for use with SynCardia Total Artificial Heart

The Freedom portable driver received FDA approval on June 26, 2014 for use with the SynCardia temporary Total Artificial Heart as a bridge to transplantation in cardiac transplant candidates who are clinically stable.

16 Jul 2014