Medical School News and Research

RSS

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

The link between severe headache disorders headaches and the body's circadian clock in pain timing and thresholds will be studied with a $2.4 million grant from the National Institute of Neurological Disorders and Stroke (NINDS) to UTHealth Houston researchers.

21 Jun 2024

Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment.

21 Jun 2024

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

Patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas (NHLs) who received frequent tests for immunoglobulin G (IgG) were less likely to experience severe infections compared with those who didn't, according to a study published in Blood Advances.

21 Jun 2024

Anakinra shows promise in reducing symptoms in patients with Sanfilippo syndrome

As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, and profound sleep disturbance.

21 Jun 2024

Super Bowl parade shooting survivors await promised donations while bills pile up

Abigail Arellano keeps her son Samuel's medical bills in a blue folder in a cabinet above the microwave. Even now, four months after the 11-year-old was shot at the Kansas City Chiefs Super Bowl parade, the bills keep coming.

21 Jun 2024

Advances in organoids and embryonic models pose no risk to personhood, expert argues

Advances in organoids and embryonic models of human development have the potential to prompt social and existential questions - e.g., what defines human individuality? However, bioethicist Insoo Hyun of Harvard Medical School and the Museum of Science in Boston says that these models have the potential to strengthen rather than weaken the concept of human individuality when considered within the philosophical frameworks of "personhood" and sentience.

20 Jun 2024

Role of SMIM1 gene in obesity uncovered

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

20 Jun 2024

Novel method for 'rationally engineering' enzymes to deliver improved performance

Scientists have prototyped a new method for "rationally engineering" enzymes to deliver improved performance.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Detecting and correcting fMRI distortions caused by arousal fluctuations

In a new study, investigators from McLean Hospital (a member of Mass General Brigham), Harvard Medical School and the National Institute on Drug Abuse – Intramural Research Program (NIDA-IRP) discovered that the tendency of people's arousal to wane over the course of brain scans has been distorting the brain connection maps produced by functional magnetic resonance imaging (fMRI).

19 Jun 2024

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.

18 Jun 2024

Rutgers Health study reveals key factors in hospice discharges leading to negative outcomes

Black patients who leave hospice care and patients with short stays in hospice care are at increased risks for being admitted to a hospital after being discharged from hospice, according to Rutgers Health researchers.

18 Jun 2024

¿Cómo se dice? California loops in AI to translate health care information

Tener gripe, tener gripa, engriparse, agriparse, estar agripado, estar griposo, agarrar la gripe, coger la influenza. In Spanish, there are at least a dozen ways to say someone has the flu — depending on the country.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

New AI tool could revolutionize clinical trial efficiency and cost

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

17 Jun 2024

Rapid test detects brain cancer mutations in cerebrospinal fluid

A test that looks for genetic hallmarks of brain cancers in samples of cerebrospinal fluid can decrease the time to diagnosis and eliminate the need for invasive brain biopsies for some patients.

17 Jun 2024

Innovative bread formulation shows promise in preventing asthma

Brazilian researchers have developed functional bread with the potential to prevent asthma, a respiratory disorder responsible for some 350,000 hospitalizations per year in the SUS (Sistema Único de Saúde), the nation's public healthcare network.

17 Jun 2024

Study offers insights into rising disposable vape use among UK youth

A new study has provided an in-depth look into the rising trend of disposable vape use among young people in the UK.

17 Jun 2024

Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

Study: Out-of-pocket costs impact naloxone access

Patients are less likely to fill prescriptions for naloxone when they face increases in out-of-pocket costs, according to research by the University of Michigan.

13 Jun 2024

Medical School News and Research

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

Anakinra shows promise in reducing symptoms in patients with Sanfilippo syndrome

Super Bowl parade shooting survivors await promised donations while bills pile up

Advances in organoids and embryonic models pose no risk to personhood, expert argues

Role of SMIM1 gene in obesity uncovered

Novel method for 'rationally engineering' enzymes to deliver improved performance

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

Detecting and correcting fMRI distortions caused by arousal fluctuations

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

Rutgers Health study reveals key factors in hospice discharges leading to negative outcomes

¿Cómo se dice? California loops in AI to translate health care information

New research explores maternal influence on brain biomarkers

New AI tool could revolutionize clinical trial efficiency and cost

Rapid test detects brain cancer mutations in cerebrospinal fluid

Innovative bread formulation shows promise in preventing asthma

Study offers insights into rising disposable vape use among UK youth

Case study sheds light on CAR-T therapy-related secondary cancers

Study: Out-of-pocket costs impact naloxone access

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News