Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Researchers discover how breast cells prevent cancer invasion

Researchers have shown that the cell layer surrounding breast milk ducts reaches out and engulfs cancerous cells to stop their spread.

30 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

Study explores occurrence and treatment of brain metastases in ROS1 lung cancer

Increasingly, doctors are treating lung cancer based on the genetic rearrangements driving the disease. For example, cancers that are driven by changes in the genes ALK, EGFR, and ROS1 can now all be paired with drugs that target these specific changes.

10 Jul 2018

Fluorescent fish could help find origins of neuroblastoma

A new type of zebrafish that produces fluorescent tags in migratory embryonic nerve precursor cells could help a Rice University neurobiologist and cancer researcher find the origins of the third-most common pediatric cancer in the U.S.

10 Jul 2018

Altitude sickness drug may offer significant gains for patients with glioblastoma

A drug used to treat altitude sickness -- as well as glaucoma, epilepsy, heart failure and seizures -- may also offer significant gains for patients with a fast-growing brain tumor known as glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.

10 Jul 2018

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs.

9 Jul 2018

Researchers develop simple blood test to predict likely spread of rare cancer

New QUT research has shed fresh light on how head and neck cancer spreads to other organs and researchers are developing a simple blood test to tell doctors which patients are at risk of spread long before conventional imaging can.

9 Jul 2018

Cilia appears to play key role in formation of melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment.

2 Jul 2018

New computational method improves ability to track spread of cancer cells

Princeton researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another.

30 Jun 2018

Research shows why new cancer therapies fail to work on some patients

University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.

30 Jun 2018

Novel smart probe may improve post-surgical outcomes for cancer patients

A new Tel Aviv University study explores a novel smart probe for image-guided surgery that may dramatically improve post-surgical outcomes for cancer patients.

26 Jun 2018

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis, and other neurodegenerative diseases.

21 Jun 2018

Study reveals new target to halt tumor growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes - tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.

21 Jun 2018

Study: Oxidative stress can be used against tumors to treat cancer

Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.

21 Jun 2018

Groundbreaking discovery could be key to preventing cancer metastasis

A groundbreaking discovery by University of Alberta researchers has identified previously-unknown therapeutic targets that could be key to preventing the spread of cancer.

21 Jun 2018

Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

With each decade of life, the likelihood of progression of melanoma after treatment with anti-PD1 immunotherapy decreased by 13 percent.

13 Jun 2018

Older melanoma patients fare better on immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research.

13 Jun 2018

New blood test better than having a needle inserted into the eye

People diagnosed with a deadly form of cancer will no longer face the prospect of having a needle inserted into their eye thanks to a new blood test developed by Edith Cowan University researchers.

12 Jun 2018

New research explores why minority children have worse cancer outcomes

New research will focus on finding better treatments for minority children with high-risk cancer malignancies - a group whose outcomes and survival rates are worse than other pediatric patients.

11 Jun 2018