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Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy.

12 Jun 2019

Brain activation patterns may help identify people at risk for developing bipolar spectrum disorder

Patterns of brain activation during reward anticipation may help identify people most at risk for developing bipolar spectrum disorders, according to a study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.

12 Jun 2019

Nurses play key role in promoting compassionate care for patients with alcohol use disorder

Nurses play a critical role in promoting compassionate care for patients and families affected by alcohol use disorder, including evidence-based medication-assisted treatment approaches, according to a paper in the July/September Journal of Christian Nursing, official journal of the Nurses Christian Fellowship.

12 Jun 2019

Findings indicate indirect link between consumption of cattle related foods and cancer

In February 2019, the German Cancer Research Centre presented findings on new infection pathogens that go by the name of “Bovine Milk and Meat Factors”.

12 Jun 2019

Study: Underweight boys and overweight girls have increased risk of depression

The results of a large community-based study have shown that the probability of major depressive disorder in children and adolescents with high, low, or normal body mass index differs according to gender.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Malaria drug may help those with hereditary hearing loss finds study

Researchers have found that anti-malarial drug artemisinin could help patients with genetic or hereditary hearing loss. The study results were published in the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS). The study was titled, “Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model.”

12 Jun 2019

CZI announces new program to drive progress in the fight against rare diseases

Today, the Chan Zuckerberg Initiative announced a new program aimed at supporting and lifting up the work that patient communities are doing to accelerate research and drive progress in the fight against rare diseases.

11 Jun 2019

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Researchers continue to dig for molecular clues to better understand how gene-environment interactions influence neuropsychiatric disease risk and resilience.

11 Jun 2019

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Researchers have found that many widely accepted dietary guidelines are not suitable for everyone, with even twins responding differently to the same foods.

11 Jun 2019

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Specialized risk scores derived from testing that calculates the cumulative effect of an individual's entire DNA sequence, the genome, may reliably predict heart disease in people who have not yet had a heart attack, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

11 Jun 2019

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for the first time succeeded in conquering a chronic infection with the hepatitis B virus in a mouse model.

11 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Using molecular biomarkers to guide the choice of therapies for metastatic pancreatic cancer

A new pilot study demonstrated the feasibility of using molecular tumor markers as the basis for selecting the chemotherapeutic agents to use in patients with metastatic pancreatic cancer.

11 Jun 2019

New case study about cannabis hyperemesis syndrome in palliative care

The medical use of cannabis is growing. Medical marijuana may improve symptoms including pain and anorexia. While it may improve nausea and vomiting, it can rarely cause a hyperemesis syndrome with chronic use.

11 Jun 2019

$Early exposure to antacids could put infants at risk for bone fractures during childhood$

Early exposure to antacids could put infants at risk for bone fractures during childhood

Infants who are given antacids in their first year of life are more likely to fracture a bone later as a child, according to a new study published June 7 in Pediatrics.

11 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

Researchers map the most common bacterial cause of pneumonia around the world

Researchers have mapped the most common bacterial cause of pneumonia around the world and revealed how these bacteria evolve in response to vaccination.

11 Jun 2019

Study looks into evolution of sex and transmissible cancer

One of the greatest enigmas of evolutionary biology is that while sex is the dominant mode of reproduction among multicellular organisms, asexual reproduction appears much more efficient and less costly.

From PLOS ONE 10 Jun 2019

Researchers compare American, Pacific and Southeast Asian subtypes of Zika virus

Over recent years, Zika virus has spread eastward from Africa and Asia, leading to an epidemic in the Americas. Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.

From PLOS ONE 10 Jun 2019

Genetic News and Research

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Brain activation patterns may help identify people at risk for developing bipolar spectrum disorder

Nurses play key role in promoting compassionate care for patients with alcohol use disorder

Findings indicate indirect link between consumption of cattle related foods and cancer

Study: Underweight boys and overweight girls have increased risk of depression

Fibrinogen a key player in health and disease, says new study

Malaria drug may help those with hereditary hearing loss finds study

CZI announces new program to drive progress in the fight against rare diseases

Early life adversity and high levels of FKBP5 protein amplify anxiety-like behavior

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

Using molecular biomarkers to guide the choice of therapies for metastatic pancreatic cancer

New case study about cannabis hyperemesis syndrome in palliative care

Early exposure to antacids could put infants at risk for bone fractures during childhood

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Researchers map the most common bacterial cause of pneumonia around the world

Study looks into evolution of sex and transmissible cancer

Researchers compare American, Pacific and Southeast Asian subtypes of Zika virus

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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