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Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

An Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome, also known as the "dark matter" of human cancer DNA.

9 Oct 2019

Chemists employ new strategy to synthesize complex natural products

Chemists from the University of Basel have succeeded in synthesizing two complex natural products from the group of dithiodiketopiperazines (DTPs).

9 Oct 2019

Study highlights potential impact of chlamydia infection on men's fertility

The potential impact of undiagnosed sexually transmitted chlamydia infection on men's fertility has been highlighted in a study led by Queensland University of Technology (QUT), which for the first time found chlamydia in the testicular tissue biopsies of infertile men whose infertility had no identified cause.

9 Oct 2019

New analysis examines the darknet's opioid purchases

U.S. overdose deaths attributed to synthetic opioids, such as fentanyl, have increased from under 3,000 in 2013 to nearly 20,000 in 2016, making up half of all opioid-related overdose deaths.

9 Oct 2019

Chemists successfully synthesize complex natural products

Chemists from the University of Basel have succeeded in synthesizing two complex natural products from the group of dithiodiketopiperazines (DTPs). For this, they employed a new strategy based on "C-H bond activation," resulting in a short and high yielding route.

9 Oct 2019

Scientists demonstrate potential method for treating advanced liver cancers

Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780,000 deaths every year.

9 Oct 2019

Lab-grown, testosterone-producing cells could help treat hypogonadism

Researchers have managed to grow human, testosterone-producing cells, which could lead to improved treatment options for low testosterone levels.

9 Oct 2019

New study examines care for patients with knee osteoarthritis in the U.S.

A new study published in Arthritis Care & Research provides an overview of U.S. physicians' recommendations for physical therapy, lifestyle counseling, pain medications for treating knee osteoarthritis.

9 Oct 2019

Scientists discover new patterns in the evolution of the influenza virus

Researchers from Skoltech have found that the devious influenza virus is capable of new patterns of evolution and mutation in order to escape treatment with the currently available drugs and prevention with the currently available vaccines. This discovery however could help researchers predict the potential mutations in the genome of the virus and ultimately help them develop and design more effective vaccines against influenza.

9 Oct 2019

Using electrically conductive biomaterials for heart repair

When a heart attack occurs, muscle in the heart tissue can be scarred, interfering with electrical activity necessary for healthy heart function. Drug treatments are available that alleviate further damage, but these don't lead to tissue regeneration.

8 Oct 2019

MedSafer helps reduce inappropriate medications prescribed to older people

The elderly are often prescribed multiple medications for different health conditions. While some medications are needed, polypharmacy and medication overload can be costly and even harmful. However, reducing the number of potentially inappropriate medications that seniors take on a daily basis is an ongoing challenge.

8 Oct 2019

X-ray crystallography can provide inaccurate information about protein structure

A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, can provide inaccurate information about a critical set of proteins - those found in cell membranes - which in turn could be leading to poor and inefficient drug design.

8 Oct 2019

Meflin protein plays a role in restraining progression of pancreatic cancer

A research team led by Nagoya University has revealed that cells containing a protein called Meflin have a role in restraining the progression of pancreatic cancer, a type of cancer that is hard to treat with traditional anti-cancer drugs.

8 Oct 2019

Novel treatment strategies could help prevent abuse of opioids, other substances

Concerns over the opioid epidemic have sparked a strong scientific interest in why some people become addicted while others don't. Now, researchers are proposing novel treatment strategies that could help prevent abuse of opioids and other substances.

8 Oct 2019

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability.

8 Oct 2019

GUMC now offers three clinical trials to study treatments for LBD

Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson's and Alzheimer's disease.

8 Oct 2019

New experimental growth factor drug appears to prevent worsening of osteoarthritis

More than 10 percent of Americans over age 60 experience knee pain related to osteoarthritis, the most common disease of the knee joint. Osteoarthritis of the knee causes pain, activity limitation, physical disability, reduced health-related quality of life and excess mortality compared with the general population.

8 Oct 2019

Innovative study aims to improve care for patients using opioids for long-term pain

Researchers at Keele University have launched an innovative study to improve care for patients who manage long-term pain using opioids.

8 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

Health care market fails to support new antibiotics against superbugs, study finds

The health care market is failing to support new antibiotics used to treat some of the world's most dangerous, drug-resistant "superbugs," according to a new analysis by University of Pittsburgh School of Medicine infectious disease scientists.

8 Oct 2019

Drugs News and Research

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

Chemists employ new strategy to synthesize complex natural products

Study highlights potential impact of chlamydia infection on men's fertility

New analysis examines the darknet's opioid purchases

Chemists successfully synthesize complex natural products

Scientists demonstrate potential method for treating advanced liver cancers

Lab-grown, testosterone-producing cells could help treat hypogonadism

New study examines care for patients with knee osteoarthritis in the U.S.

Scientists discover new patterns in the evolution of the influenza virus

Using electrically conductive biomaterials for heart repair

MedSafer helps reduce inappropriate medications prescribed to older people

X-ray crystallography can provide inaccurate information about protein structure

Meflin protein plays a role in restraining progression of pancreatic cancer

Novel treatment strategies could help prevent abuse of opioids, other substances

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

GUMC now offers three clinical trials to study treatments for LBD

New experimental growth factor drug appears to prevent worsening of osteoarthritis

Innovative study aims to improve care for patients using opioids for long-term pain

Study receives NCI grant to explore better treatment for brain tumors in children

Health care market fails to support new antibiotics against superbugs, study finds

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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