Genetic News and Research

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Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Mutations in 'junk' DNA can cause autism, study shows

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.

27 May 2019

Artificial intelligence technique identifies new class of mutations behind autism

Many mutations in DNA that contribute to disease are not in actual genes but instead lie in the 99% of the genome once considered "junk." Even though scientists have recently come to understand that these vast stretches of DNA do in fact play critical roles, deciphering these effects on a wide scale has been impossible until now.

27 May 2019

Investigating RNA-based regulation of the cardiovascular system

Goethe University and TU Munich have jointly obtained a new Collaborative Research Centre (Sonderforschungsbereich - SFB), which will receive approximately € 11 million in funding from the German Research Foundation over the next four years.

27 May 2019

Coat of proteins makes viruses more infectious and facilitates plaque formation in Alzheimer's

New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface.

27 May 2019

Novel method for evaluating genomic sequencing results in newborn screening

Newborn screening is required in the U.S. and differs slightly depending on which state you live in. For the most part, it's done before a newborn baby leaves the hospital and includes a blood test that screens for 30-50 serious health problems that usually arise in infancy or childhood, and could hinder normal development.

26 May 2019

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation.

25 May 2019

Study demonstrates the concept of systemic gene therapy treatment for gamma-sarcoglycanopathy

Gamma-sarcoglycanopathy is one of the most common limb-girdle myopathies.

25 May 2019

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

James Wilson, MD, PhD, recalls being struck by the devastating toll of rare diseases as a young physician in the 1980s. He set out on a path to correct the genes that cause these conditions, including spinal muscle atrophy (SMA), the most common inherited fatal disease in infants.

25 May 2019

New statement emphasizes need for special multidisciplinary clinical programs

With a better understanding of how various heart conditions are inherited, and the availability of faster and less expensive genetic testing, there is need for more specialized multidisciplinary clinical programs that combine focused expertise in heart disease and genetics, according to a new statement from the American Heart Association, the world's leading voluntary organization focused on heart and brain health.

25 May 2019

LMU microbiologists characterize structure of gastric bacterium population in individual patients

Helicobacter pylori, a globally distributed gastric bacterium, is genetically highly adaptable. Microbiologists at Ludwig-Maximilians-Universitaet in Munich have now characterized its population structure in individual patients, demonstrating an important role of antibiotics for its within-patient evolution.

25 May 2019

Are fruit fly 'avatars' the next step in personalized medicine?

Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer.

24 May 2019

New UCI-led study shows crowdsourced traffic data could reduce mortality

A new UCI-led pilot study finds, on average, Waze "crash alerts" occur two minutes and 41 seconds prior to their corresponding California Highway Patrol (CHP)-reported crash.

24 May 2019

Johns Hopkins researchers develop method to map retinal cell development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.

24 May 2019

Cornell University-led study creates new standard genome for widely researched worm

A new Cornell University-led study finds that the genome for a widely researched worm, on which countless studies are based, was flawed. Now, a fresh genome sequence will set the record straight and improve the accuracy of future research.

24 May 2019

Researchers develop simple, quick technique for gene editing in rice blast fungus

CRISPR/Cas9 is now a household name associated with genetic engineering studies.

24 May 2019

Zebrafish embryo could help better understand the potential underpinnings of brain disorders

A close look at the rapidly developing zebrafish embryo is helping neuroscientists better understand the potential underpinnings of brain disorders, including autism and schizophrenia.

24 May 2019

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

24 May 2019

Scientists examine hormonal links between diet and obesity

Obesity is a growing public health crisis, bringing with it many serious risk factors, including cardiovascular disease and type 2 diabetes.

24 May 2019

Children's Tumor Foundation establishes significant research initiative to combat NF2

On the occasion of World NF2 Awareness Day, the Children's Tumor Foundation has announced the establishment of a significant research initiative dedicated to finding effective treatments for NF2, along with a substantial investment of $2.3 million in this bold new effort.

23 May 2019

Genetic News and Research

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Mutations in 'junk' DNA can cause autism, study shows

Artificial intelligence technique identifies new class of mutations behind autism

Investigating RNA-based regulation of the cardiovascular system

Coat of proteins makes viruses more infectious and facilitates plaque formation in Alzheimer's

Novel method for evaluating genomic sequencing results in newborn screening

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

Study demonstrates the concept of systemic gene therapy treatment for gamma-sarcoglycanopathy

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

New statement emphasizes need for special multidisciplinary clinical programs

LMU microbiologists characterize structure of gastric bacterium population in individual patients

Are fruit fly 'avatars' the next step in personalized medicine?

New UCI-led study shows crowdsourced traffic data could reduce mortality

Johns Hopkins researchers develop method to map retinal cell development

Cornell University-led study creates new standard genome for widely researched worm

Researchers develop simple, quick technique for gene editing in rice blast fungus

Zebrafish embryo could help better understand the potential underpinnings of brain disorders

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Scientists examine hormonal links between diet and obesity

Children's Tumor Foundation establishes significant research initiative to combat NF2

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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