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'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

Food science principles help scientists to understand inner workings of cellular compartments

Johns Hopkins Medicine researchers report that food science principles have helped them determine how unusual droplets within cells stay organized and avoid dissolving into the rest of the cell's gelatinous interior.

9 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

Cellular program could turn T cells into effective cancer killers

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

9 Sep 2021

Novel combination therapy may prolong viral suppression in patients with HIV

A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study published in Science Translational Medicine.

9 Sep 2021

Scientists create a novel cell model for understanding human development

The earliest moments of human development—between the time of fertilization and when the embryo implants in the womb—have remained opaque to scientists.

9 Sep 2021

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Many diseases have their origin in early human development, and today (8th September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this.

9 Sep 2021

Salt tasting cells drive food foraging strategy in nematode worms

Neuroscientists have developed a computer model to explain how a nematode worm searches for food, revealing that single brain cells can both sense the environment and control a whole animal's foraging strategy.

9 Sep 2021

Are bat retroviruses a threat to humans?

Zoonotic viruses that bats transmit are capable of infecting humans and have caused devastating infections throughout the world.

9 Sep 2021

Researchers develop artificial inorganic cell-like structures to recreate functions of living cells

Researchers have developed artificial cell-like structures using inorganic matter that autonomously ingest, process, and push out material - recreating an essential function of living cells.

9 Sep 2021

Research probes interaction between SARS-CoV-2 and influenza

Researchers from Germany and France tried to determine if epidemiological studies based on co-detection prevalence data can offer a reliable estimation of interactions among respiratory viruses. They designed a simulation study by building on a general epidemiological model of co-circulation of 2 respiratory viruses that cause seasonal epidemics.

8 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

People with rare disorders that cause shortened telomeres — protective caps that sit at the end of chromosomes — may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome.

8 Sep 2021

“Batman Sam” fights cancer with care from Johns Hopkins Children’s Center

"What the heck is happening?" recalls Melissa Southward, the mother of now-three-year-old Sam, when he started having nose bleeds and developed a yellowish skin color in August 2020.

8 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

$New tool can rapidly quantify T cell fraction and predict immunotherapy response$

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies.

8 Sep 2021

Research reveals a new role for platelets in COVID-19 blood vessel damage

Abnormal crosstalk between blood platelets and cells lining blood vessels is one cause of deadly organ damage in patients with severe COVID-19, a new study finds.

8 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

Natural killer cells mediate a trade-off between wound healing and bacterial defense

Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds.

8 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

B Cell News and Research

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

Food science principles help scientists to understand inner workings of cellular compartments

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

Cellular program could turn T cells into effective cancer killers

Novel combination therapy may prolong viral suppression in patients with HIV

Scientists create a novel cell model for understanding human development

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Salt tasting cells drive food foraging strategy in nematode worms

Are bat retroviruses a threat to humans?

Researchers develop artificial inorganic cell-like structures to recreate functions of living cells

Research probes interaction between SARS-CoV-2 and influenza

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

“Batman Sam” fights cancer with care from Johns Hopkins Children’s Center

The role of nanobodies in capturing and containing SARS-CoV-2

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Research reveals a new role for platelets in COVID-19 blood vessel damage

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Natural killer cells mediate a trade-off between wound healing and bacterial defense

People living with HIV have higher risk of sudden cardiac death, finds study

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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