Gastrointestinal Tract News and Research

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Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Vaccine against group B streptococcus

Common bacteria that live harmlessly in the gastrointestinal tract and vagina of 25 percent of women can become lethal if a newborn gets exposed to them during birth.

20 Sep 2005

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics.

4 Aug 2005

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

2 Aug 2005

Breathing in large quantities of salt particles has just the same effect on blood pressure as eating a salty diet

Workers in salt factories, who inhale large amounts of salt particles, are at risk of high blood pressure due to the increased salt intake.

25 Jul 2005

Preclinical data suggest CuraGen's Velafermin may protect the gastrointestinal tract and decrease associated toxicity following exposure to radiation

New preclinical data on velafermin (CG53135), CuraGen's Phase II clinical product being developed for the prevention of oral mucositis (OM), suggesting that velafermin may protect the gastrointestinal tract and decrease associated toxicity, including enteritis and diarrhea, following exposure to radiation.

1 Jul 2005

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents, compared with placebo, according to an article in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Detox diets unsound science and do not work

Scientists say there is no proof that Detox diets work and they do no more to rid the body of toxins than the body's own natural system.

8 Jun 2005

Incretin hormones, a new wave of promising diabetes research

A new understanding of specialized incretin (or gut) hormones may lead to significant advances in the treatment and management of type 2 diabetes. This conclusion and other recent research were reported recently at the 14th Annual Meeting and Clinical Congress of the American Association for Clinical Endocrinologists (AACE) in Washington, DC.

23 May 2005

Nutrition gene key in regulating immune system

A gene that signals a yeast cell to make bread rise and mice to eat a better diet also helps selectively silence the immune system, researchers have found.

18 May 2005

Rifaximin is effective in preventing attacks of diarrhea

An antibiotic can be safely used to prevent attacks of diarrhea that plague millions of globe-trotting vacationers and business travelers, a Houston research team reports this week in the Annals of Internal Medicine.

17 May 2005

Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

In this week's journal Nature, scientists at the Salk Institute for Biological Studies report that they have solved one of the "holy grail" puzzles of developmental biology: the existence of a mechanism that insures that the exterior of our bodies is symmetrical while inner organs are arranged asymmetrically.

11 May 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Autistic children found to have abnormal metabolic profile

Autism, a neurodevelopment disorder which has increased tenfold over the last 15 years, now affects 30 of every 10,000 children in the United States.

4 Apr 2005

Children with autism have a severely abnormal metabolic profile

Chronic biochemical imbalance is often a primary factor in the development of many complex diseases but a possible metabolic basis for autism has not been well explored. Now Arkansas Children's Hospital Research Institute researchers report for the first time that children with autism have a severely abnormal metabolic profile indicating increased vulnerability to oxidative stress.

3 Apr 2005

Live laparoscopic banding surgery to be broadcast over the World Wide Web

The University of Alabama at Birmingham (UAB) will broadcast its first real-time live surgery over the World Wide Web on April 5, 2005 at 12:00pm (CDT) 1:00pm (EDT). The surgery, called laparoscopic banding, is a relatively new treatment for obesity. The Webcast is part of UAB's continuing effort to familiarize doctors with the latest surgical techniques, and allows the public a real-time look at medical advances.

29 Mar 2005

Small is beautiful in the medical world

Small is beautiful in the medical world. And being able to give European industry the edge in a nearly €200 billion worldwide biomedical market is what drives a consortium of EU-backed partners to make and market smaller, cheaper and better biomedical devices and innovative new applications.

19 Jan 2005

Diagnosis of tuberculosis in young children can be confirmed by a straightforward sputum test

Diagnosis of tuberculosis is difficult in infants and young children and can be complicated by HIV infection. Heather Zar (School of Child and Adolescent Health, University of Cape Town, South Africa) and colleagues studied 250 children aged 1 month to 5 years who were admitted for suspected pulmonary tuberculosis in Cape Town. Sputum induction and gastric lavage were done on three consecutive days according to a standard procedure.

7 Jan 2005

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

If you want to avoid allergies or asthma, scientists at the University of Michigan Medical School suggest you start paying more attention to what's in your gut.

23 Dec 2004