Immune Response News and Research

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Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

Mutations on a key SARS-CoV-2 viral protein are linked to extreme immune responses and could offer a novel vaccine target.

27 Sep 2023

Researchers discover how Zika virus persists in the placenta

Before SARS-CoV-2 and the COVID-19 pandemic, there was the Zika virus epidemic, lasting from 2015 to 2016. The Zika virus can cause serious birth defects and abnormalities.

26 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

One gene variant could be a shield against severe COVID-19 lung damage

Researchers identify a specific genetic variant, rs2204985, linked to less severe lung involvement and a stronger immune response in COVID-19 patients with severe pneumonia. The study suggests that understanding this genetic marker could help identify high-risk individuals and enhance strategies for prevention and treatment.

25 Sep 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy - one that boosts T cells, and another that boosts dendritic cells - can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

Engineered mice reveal how Omicron subvariant BA.5 is more virulent

New research used engineered mice to compare SARS-COV-2 omicron subvariants and found one of them – BA.5 – was more virulent likely due to its ability to rapidly replicate early during infection.

25 Sep 2023

Future-proof vaccine candidate protects against wide range of coronaviruses

Studies of a 'future-proof' vaccine candidate have shown that just one antigen can be modified to provide a broadly protective immune response in animals.

25 Sep 2023

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

The power of nanobodies: How they impact COVID-19 immune response

The structures of 340 antibodies (Abs) and 83 nanobodies.

25 Sep 2023

Long-term consumption of ultra-processed foods may increase depression risk

The effects of ultra-processed food (UPF) on mental health.

25 Sep 2023

New insights into the molecular mechanism of protein degradation

Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Community-acquired pneumonia (CAP) is a major infectious disease worldwide and contributes to high mortality and massive economic burden. Hospital mortality among the severe CAP (SCAP) remains high, ranging from 25% to more than 50%.

22 Sep 2023

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

A clinical trial has launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial.

22 Sep 2023

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Macrophages are little cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions.

22 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it.

21 Sep 2023

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

A study has revealed new details about a key population of immune system cells critical to successful vaccination against the pandemic virus, SARS-CoV-2.

21 Sep 2023

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

A trial of a preventive HIV vaccine candidate has begun enrollment in the United States and South Africa.

20 Sep 2023

Immune Response News and Research

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

Researchers discover how Zika virus persists in the placenta

Monkeypox mimics smallpox vaccine's immune response, new study reveals

Intranasal vaccine shows promise against COVID variants in hamsters

One gene variant could be a shield against severe COVID-19 lung damage

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Engineered mice reveal how Omicron subvariant BA.5 is more virulent

Future-proof vaccine candidate protects against wide range of coronaviruses

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

The power of nanobodies: How they impact COVID-19 immune response

Long-term consumption of ultra-processed foods may increase depression risk

New insights into the molecular mechanism of protein degradation

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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