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Accumulated brain protein affects genes in Alzheimer's disease

A new study published in February 2020 in the journal Cell Reports shows how the build-up of specific brain cell proteins are linked to altered gene expression that causes the symptoms of Alzheimer's disease (AD).

11 Feb 2020

Nerve insulation renewed to create long-term learning

A new study published in February 2020, in the journal Nature Neuroscience, shows that short-term learning occurs rapidly, but for it to become a long-term memory, brain cells must form more myelin, an insulating fatty material.

10 Feb 2020

Researchers culture human blood-brain barrier on a chip

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's or cancer from getting into the brain.

10 Feb 2020

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL.

10 Feb 2020

Scientists measure how sensory stimuli are processed in the brain

If we cross a road with our smartphone in view, a car horn or engine noise will startle us. In everyday life we can easily combine information from different senses and shift our attention from one sensory input to another - for example, from seeing to hearing.

10 Feb 2020

Defining neurogenic niche proteome helps identify key regulators of neurogenesis

In mammalian adult brains, neural stem cells are only present in few specific parts, so called niches. Only these niches are capable of generating new neurons.

7 Feb 2020

Breathing pattern may help predict 'when' people begin voluntary action

Have you ever gone ahead and eaten that piece of chocolate, despite yourself?

6 Feb 2020

Unique neuron that computes like a compass identified

It's 5 p.m. as you leave the parking garage at work, but you realize you have no idea which way to turn to travel home. You know where you are and what street your house is on--it's just that you can't remember how to get there.

5 Feb 2020

Flickering light triggers the brain to release signaling chemicals that may help fight Alzheimer's

For over a century, Alzheimer's disease has confounded all attempts to treat it. But in recent years, perplexing experiments using flickering light have shown promise.

4 Feb 2020

Scientists shed new light on neuronal circuits that acquire and update voluntary actions

Two types of neuronal circuit in the brain that acquire and update voluntary actions are much more intertwined than previously thought.

3 Feb 2020

New genetic screen for Huntington’s disease

Huntington’s disease is a genetic disease that is debilitating and progressive leading to severe brain damage and eventual death. In patients with this autosomal dominant disease, there is presence of a protein called the Huntingtin protein that forms clumps within the brain leading to the symptoms of the disease.

30 Jan 2020

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

Typical examples include paralysis due to a spinal cord injury and visual field atrophy or even complete blindness due to optic nerve atrophy in glaucoma patients.

30 Jan 2020

Researchers examine abnormal neuron activity in Rett syndrome

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and key developmental periods pass, the brain becomes less malleable--but certain experiences create opportunities for parts of the adult brain to rewire and learn again.

29 Jan 2020

Buck study uncovers how astrocyte senescence promotes neurodegeneration

Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies.

29 Jan 2020

Advancing birth triggers an early start to neuron death, mice study shows

Moving birth a day early triggers an early start to widespread neuron death, according to new research in mice published in eNeuro.

28 Jan 2020

Findings shed new light on how striatum processes information to plan, execute movements

Researchers at Karolinska Institutet have mapped how different nerve cells in the brain area striatum process information to plan and execute our movements at just the right time and with the right vigour. The results, presented in the journal Cell Reports, show that different cell types in the striatum receive signals from completely different parts of the cerebral cortex and thus respond to different types of information.

28 Jan 2020

Study suggests prenatal origin for ‘young’ Parkinson’s disease

A new study published in the journal Nature Medicine on January 2020 suggests that Parkinson’s disease developing before the age of 50 years could be due to an abnormality in certain brain cells that remains dormant until the age of onset of the disease. It also indicates the potential usefulness of a specific drug to prevent this by correcting the brain cell disorder.

27 Jan 2020

Scientists reveal the damaging effect of Zika virus on a type of brain cell

The Zika virus (ZIKV) outbreak in Brazil in 2015 sparked for many health agencies and scientists to study the pathogen, which has been linked to microcephaly and other fetal neurological disorders collectively known as Congenital Zika Syndrome.

27 Jan 2020

Parkinson's disease may affect brain cells before birth

People who develop Parkinson's disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new Cedars-Sinai research. The research points to a drug that potentially might help correct these disease processes.

27 Jan 2020

New insights into globular glial tauopathy could aid in the design of better drugs

Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of phospho-tau, in other words tau associated to phosphate groups.

27 Jan 2020

Neuron News and Research

Accumulated brain protein affects genes in Alzheimer's disease

Nerve insulation renewed to create long-term learning

Researchers culture human blood-brain barrier on a chip

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Scientists measure how sensory stimuli are processed in the brain

Defining neurogenic niche proteome helps identify key regulators of neurogenesis

Breathing pattern may help predict 'when' people begin voluntary action

Unique neuron that computes like a compass identified

Flickering light triggers the brain to release signaling chemicals that may help fight Alzheimer's

Scientists shed new light on neuronal circuits that acquire and update voluntary actions

New genetic screen for Huntington’s disease

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

Researchers examine abnormal neuron activity in Rett syndrome

Buck study uncovers how astrocyte senescence promotes neurodegeneration

Advancing birth triggers an early start to neuron death, mice study shows

Findings shed new light on how striatum processes information to plan, execute movements

Study suggests prenatal origin for ‘young’ Parkinson’s disease

Scientists reveal the damaging effect of Zika virus on a type of brain cell

Parkinson's disease may affect brain cells before birth

New insights into globular glial tauopathy could aid in the design of better drugs

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