RNA Sequencing News and Research

RSS

Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

New technology for profiling genetic makeup of myeloma tumor cells developed

Cancer arises when cells lose control. Deciphering the "blueprint" of cancer cells - outlining how cancer cells hijack specific pathways for uncontrolled proliferation - will lead to more efficient ways to fight it.

7 Dec 2018

Novel approach gives new insights into formation of neurons in mammalian adult brain

A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Texas Children's Hospital has developed a powerful new approach to understand the formation of new neurons in the mammalian adult brain.

5 Dec 2018

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

In certain forms of cancer, connective tissue forms around and within the tumor. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumor in different ways.

4 Dec 2018

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

The New York Genome Center has received approval from the New York State Department of Health to offer whole genome and RNA transcriptome sequencing in its Clinical Laboratory Evaluation Program-certified laboratory.

29 Nov 2018

Revolutionary new technology sheds light on why cancers form in specific cell types

While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms.

29 Nov 2018

Researchers map cells in the early human placenta to shed light on pregnancy complications

To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to date has focused on those later stages of pregnancy. But the biological events that lead to these problems could start much earlier.

28 Nov 2018

New method enhances efficiency and accuracy of single cell RNA sequencing

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.

22 Nov 2018

Brain and muscle cells found within kidney organoids

Researchers have discovered the presence of rogue brain and muscle cells inside kidney organoids and used artificial intelligence to remove them.

15 Nov 2018

Researchers develop tool that speeds up analysis and publication of biomedical data

Researchers at the Icahn School of Medicine at Mount Sinai have developed a tool that speeds up the analysis and publication of biomedical data from many months or years to mere minutes, transforming the way researchers communicate results of their studies.

15 Nov 2018

Neural networks could replace marker genes in RNA sequencing

Researchers have used neural networks and supervised machine learning techniques to characterize cell types following single-cell RNA sequencing.

13 Nov 2018

Study provides new clues to origin and development of multiple sclerosis

Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis, shows that they might have a significant role in the development of the disease.

12 Nov 2018

UCLA researchers investigate how a protein factor contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.

1 Nov 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads to blocked arteries, by looking at how cells in our blood vessels change their function.

1 Nov 2018

Map of human liver cells reveals molecular make-up of individual cells

A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.

From 10x Genomics, Inc. 23 Oct 2018

Texas A&M and UTA establish Texas Genomics Core Alliance

Texas A&M University and The University of Texas at Arlington have established The Texas Genomics Core Alliance to increase access to and decrease costs of cutting-edge, high-throughput genomics sequencing technologies.

22 Oct 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

Study uncovers important role of PRMT1 in dilated cardiomyopathy

In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy.

16 Oct 2018

Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

RNA Sequencing News and Research

Researchers explore how glial cells develop in the brain from neural precursor cells

New technology for profiling genetic makeup of myeloma tumor cells developed

Novel approach gives new insights into formation of neurons in mammalian adult brain

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

Revolutionary new technology sheds light on why cancers form in specific cell types

Researchers map cells in the early human placenta to shed light on pregnancy complications

New method enhances efficiency and accuracy of single cell RNA sequencing

Brain and muscle cells found within kidney organoids

Researchers develop tool that speeds up analysis and publication of biomedical data

Neural networks could replace marker genes in RNA sequencing

Study provides new clues to origin and development of multiple sclerosis

UCLA researchers investigate how a protein factor contributes to cancer cell migration

Scientists decode the longest ever continuous DNA sequence

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

Map of human liver cells reveals molecular make-up of individual cells

Texas A&M and UTA establish Texas Genomics Core Alliance

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

Study uncovers important role of PRMT1 in dilated cardiomyopathy

Research shows basophils are key players in lung development

Sequencing & Genomics: Elevating Science and Healthcare eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology