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Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

SARS-CoV-2 infection damages CD8+ T cell response

In a recent study published in the journal Immunity, a team of researchers from the United States found that previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reduce the activation and expansion of CD8+ T cells in response to coronavirus disease 2019 (COVID-19) vaccinations.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

In a recent study published in the journal Nutrients, researchers at Johns Hopkins Medicine reviewed the beneficial properties of green tea in alleviating symptoms of benign gynecological disorders.

21 Mar 2023

Shorter ejaculation abstinence times linked to better reproductive outcomes during fertility treatments

Researchers evaluate the association between ejaculatory abstinence time, rates of pregnancies and live births, and DNA fragmentation.

20 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

Bacteria require phase separation to thrive in the mammalian gut

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study in mice.

17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).

16 Mar 2023

MS relapse risk not likely to increase after fertility treatments, study finds

There's good news for those with multiple sclerosis (MS). A new study has found that female participants were no more likely to have a flare-up of the disease after receiving fertility treatments than they were before their treatments.

16 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Is green leaf biomass a viable and sustainable source of protein?

In a recent study published in the journal Nutrients, researchers at North Carolina State University reviewed studies on underutilized sources of plant proteins and discussed strategies to enhance yields, extract nutrients and influence the demand and acceptance of new protein sources, especially green leaf biomass.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

ANDRONET COST Action aims to improve research, education, and public awareness in andrology

Raising awareness of male health: ANDRONET COST Action to improve research, education, and public awareness in the field of andrology.

13 Mar 2023

in vitro News and Research

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

SARS-CoV-2 infection damages CD8+ T cell response

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

Shorter ejaculation abstinence times linked to better reproductive outcomes during fertility treatments

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

Bacteria require phase separation to thrive in the mammalian gut

Does vitamin D play an anti-viral role against SARS-CoV-2?

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

MS relapse risk not likely to increase after fertility treatments, study finds

New biomimetic model helps study wound healing in burn and laceration wounds

An emerging target for chronic kidney disease treatment - DNA-PKcs

A convergent coexpression approach identifies novel genes associated with autism

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Is green leaf biomass a viable and sustainable source of protein?

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

ANDRONET COST Action aims to improve research, education, and public awareness in andrology

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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