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Targeting specific enzyme could combat Alzheimer’s disease on two fronts

UQ researchers have discovered a potential drug target for Alzheimer’s disease — an enzyme which has effects on both the immune and nervous systems.

19 Sep 2019

KHN’s ‘What the Health?’: Tennessee seeks Medicaid changes

Tennessee announced this week that it hopes to become the first state to take the Trump administration up on its offer to transform funding for its Medicaid program into a block grant.

19 Sep 2019

Stem cells with 'dual identity' associated with loss of smell from inflammation in chronic sinusitis

In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis.

19 Sep 2019

Diabetes drug can also be used to treat heart failure

Dapagliflozin, a drug that is already used to successfully treat type 2 diabetes (T2D) and prevent development of heart failure, can also be used to treat pre-existing heart failure, even in patients without T2D.

19 Sep 2019

Review highlights medication underuse in the treatment of opioid use disorder

Though research shows that medication-assisted treatment can help people who are addicted to opioids, the three drugs approved by the Food and Drug Administration (FDA) are underused, according to a review of current medical data on opioid addiction in the U.S.

19 Sep 2019

Salmonella responsible for bloodstream infections in sub-Saharan Africa exhibits extensive drug resistance

The first extensively drug-resistant strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo.

19 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

New uses for CBD in genetic brain disorder

A new study has revealed that cannabidiol can help people with a rare brain condition called Angelman syndrome to improve their behavioral traits and to control seizures.

19 Sep 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Diarrhea linked significantly to weight gain

A study has shown that obesity is linked to chronic diarrhea, independent of other lifestyle or eating habits.

19 Sep 2019

Researchers join new project to eliminate animal testing

Researchers at the University of California, Riverside, are part of an ambitious plan at the U.S. Environmental Protection Agency, or EPA, to eliminate animal testing by 2035.

19 Sep 2019

Doctors and nurses with addictions often denied a crucial recovery option

Dr. Wesley Boyd, an associate professor of psychiatry at Harvard, has spent years working with state programs that help doctors, nurses and other health care workers who have become addicted to opioids get back on their feet professionally.

19 Sep 2019

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

What if a drug that sits in nearly everyone's medicine cabinet could help extend the lives of some cancer patients? In companion presentations at the American Society for Therapeutic Radiation Oncology Annual Meeting in Chicago, doctors from Roswell Park Comprehensive Cancer Center report new evidence that low-dose aspirin and other anti-inflammatories may improve survival in patients undergoing treatment for some head/neck and lung cancers.

19 Sep 2019

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

A technology that manipulates microRNAs developed by Jingfang Ju, PhD, a biochemist and Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University, and colleagues has shown promise when used as anti-cancer therapeutic.

19 Sep 2019

Study may provide best intervention measures to prevent opioid overdose

A minority of people who use illicit opioids indicated a preference for fentanyl, the super-potent synthetic opioid that accounts for much of the recent rise in U.S. overdose deaths, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

19 Sep 2019

Nearly half of NCI-sponsored trials on clinical cancer were associated with new drug approvals

A new study shows that nearly half of phase 3 cancer clinical trials carried out by the National Cancer Institute (NCI)-sponsored SWOG Cancer Research Network, one of five groups in NCI's National Clinical Trials Network (NCTN), were associated with clinical care guidelines or new drug approvals. NCI is part of the National Institutes of Health.

19 Sep 2019

Study opens a promising new front in the fight against pancreatic cancer

Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to cancer-fighting drugs.

19 Sep 2019

Early combination therapy provides long-term benefits for patients with type 2 diabetes

A new study, VERIFY (Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of type 2 diabetes) presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (16-20 Sept, 2019), and published simultaneously in The Lancet, is the first to show that early combination therapy using vildagliptin and metformin in patients newly diagnosed with type 2 diabetes (T2D) leads to better long-term blood sugar control and a reduced rate of treatment failure than metformin alone.

19 Sep 2019

Antibiotic resistance is transferring from humans to animals

Resistance to antibiotics could be moving from humans to animals, research by a Clemson University professor has shown. The research details results that demonstrate reverse zoonosis, a process by which humans infect other species of animal with diseases.

18 Sep 2019

New device uses electromagnetic waves to reverse Alzheimer’s

A new study, to be published in the September 3, 2019, issue of the Journal of Alzheimer's Disease, provides something to cheer about for the estimated 44 million patients who have Alzheimer’s disease (AD) in the US, and their hard-pressed caregivers.

18 Sep 2019