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Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

3 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

An accepted manuscript published in the American Journal of Roentgenology (AJR) found that deploying a radiomic-based model with T2-weighted MRI data could increase diagnostic accuracy for pediatric Crohn disease (CD).

3 Aug 2023

Expression of two key genes influences cancer progression

Tissues, blood vessels, cells: tumours develop in a complex ecosystem known as the tumour microenvironment.

3 Aug 2023

Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

Simple interview technique could help detect early signs of dementia

Research at the Florida State University College of Medicine has identified a potential low-cost method for predicting if a person is at risk of developing dementia.

3 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023

COVID-19's impact on persons with disabilities in Africa

In 2017, a road accident left Anna Nzioka with two fractures in her right leg. After a series of operations and physiotherapy, she has slowly learned to walk again, although with the aid of a crutch.

3 Aug 2023

Gut microbiome changes have significant effects on cocaine use and cravings

According to the 2021 National Survey on Drug Use and Health, 4.8 million people (ages 12 and up) reported using cocaine within the previous 12 months, and 24,486 people died from an overdose involving cocaine.

3 Aug 2023

Dopamine neurons may play a bigger role in motor control than previously thought

Dopamine: It's not just for rewards anymore. In a new Northwestern University-led study, researchers identified and recorded from three genetic subtypes of dopamine neurons in the midbrain region of a mouse model.

3 Aug 2023

New study finds no link between common fungus and pancreatic cancer

Four years ago, a report that a common species of fungus might fuel pancreatic cancer offered a promising new view of the deadly disease.

3 Aug 2023

Virginia Tech student receives NSF support to pursue new line of research into the health impact of ultra-processed foods

Zach Hutelin, a doctoral candidate in the Virginia Tech's Translational Biology, Medicine, and Health (TBMH) Graduate Program, has been awarded a prestigious National Science Foundation fellowship to pursue a new line of research into the health impact of ultra-processed foods.

3 Aug 2023

Research sheds light on the causes of endometriosis-related pelvic pain

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to identify new drugs to improve symptoms and quality of life.

3 Aug 2023

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has demonstrated that it can predict the outcome of Phase II to Phase III clinical trial success using its proprietary transformer-based AI clinical trial prediction tool called inClinico with a high degree of accuracy.

3 Aug 2023

Medicine News and Research

Gene expression ratio linked to prognosis in solid tumors

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

Expression of two key genes influences cancer progression

Surprising new role for a key immune regulator revealed

Simple interview technique could help detect early signs of dementia

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

COVID-19's impact on persons with disabilities in Africa

Gut microbiome changes have significant effects on cocaine use and cravings

Dopamine neurons may play a bigger role in motor control than previously thought

New study finds no link between common fungus and pancreatic cancer

Virginia Tech student receives NSF support to pursue new line of research into the health impact of ultra-processed foods

Research sheds light on the causes of endometriosis-related pelvic pain

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

Virtual reality-based exercises found to reduce depression and anxiety among individuals treated with hemodialysis

Pharmatech: The Art of AI-Driven Drug Design with Exscientia

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

TU Graz researchers gain new insights into a light-activated protein switch

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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