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$4 million NIH award will help establish UCI Skin Biology Resource-based Center

With nearly $4 million in funding from the National Institute of Arthritis & Musculoskeletal & Skin Diseases, the University of California, Irvine will establish the UCI Skin Biology Resource-based Center.

23 Apr 2019

UAB receives $17 million grant to explore immune cells in inaccessible tissues of the human body

University of Alabama at Birmingham researchers will receive $17.8 million in federal funding to attack a key "knowledge gap" in human immunology -- how the B cells and antibody-secreting cells that reside in tissues and organs differ from those found in blood.

23 Apr 2019

Reviving the heart's regenerative capacities using microRNAs

Once the heart is fully formed, the cells that make up heart muscle, known as cardiomyocytes, have very limited ability to reproduce themselves. After a heart attack, cardiomyocytes die off; unable to make new ones, the heart instead forms scar tissue. Over time, this can set people up for heart failure.

23 Apr 2019

Scientists identify 104 high-risk genes for schizophrenia

Using a unique computational "framework" they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia.

23 Apr 2019

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Many individuals forced to fight an exceptionally aggressive form of the blood cancer acute myeloid leukemia (AML) don't survive more than five years.

22 Apr 2019

Potential of liquid biopsy in cancer biomarker detection and prenatal testing

The promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of cancer biomarkers to enable improved and personalized therapy, is the focus of a new special issue of Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

22 Apr 2019

Study seeks to better understand the genetic causes for hypospadias

Daniel Casella, M.D., a urologist at Children's National, was honored with an AUA Mid-Atlantic Section William D. Steers, M.D. Award, which provides two years of dedicated research funding that he will use to better understand the genetic causes for hypospadias.

22 Apr 2019

New scoring system based on genetic markers predicts obesity risk at birth

Researchers have come up with a scoring system based on genetic markers that predicts an individual's inborn risk for obesity.

19 Apr 2019

Improving the quality of digital pathology imaging

There's a low-tech problem troubling the high-tech world of digital pathology imaging.

19 Apr 2019

Scientists deploy CRISPR gene-editing tool to engineer multiple edits

Scientists at Christiana Care Health System's Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal.

19 Apr 2019

Synthetic biologists add analog-to-digital signal processing to genetic circuitry of living cells

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells.

19 Apr 2019

Newly developed model predicts salmonella outbreaks several months in advance

Australia has more salmonella outbreaks than any other country in the world, with the number of cases doubling over the last decade.

19 Apr 2019

Novel system enables researchers to study bacteria within mini-tissues in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology.

19 Apr 2019

Researchers identify key clues to brain and pancreas development

Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas.

19 Apr 2019

Two new epigenetic regulators maintain self-renewal of embryonic stem cells

Embryonic stem cells have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body.

19 Apr 2019

Study compares effectiveness and cost of gene therapy and HSCT in major beta-thalassemia

Gene therapy offers the promise of a cure for beta-thalassemia and a new study has shown that it is associated with fewer complications and hospital admissions over 2 years than treatment by allogeneic hematopoietic stem cell transplantation

18 Apr 2019

New gene therapy cures babies with fatal 'Bubble Boy' disease

A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease.

18 Apr 2019

Maternal age has no effect on IVF success, conclude researchers

Researchers have shown that maternal age may not influence the implantation potential of embryos in IVF or the likelihood of miscarriage.

18 Apr 2019

Study identifies how enterococci bacteria cause antibiotic-resistant bloodstream infections

A new study led by a research team from Massachusetts Eye and Ear and Harvard Medical School describes how bacteria adapted to the modern hospital environment and repeatedly cause antibiotic-resistant bloodstream infections.

17 Apr 2019