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Study finds ‘superbug’ in hands or nostrils of patients staying in the hospital

For decades, hospitals have worked to get doctors, nurses and others to wash their hands and prevent the spread of germs.

15 Apr 2019

New genetic treatment removes antibiotic resistance from bacteria

Jane and Aatos Erkko foundation has awarded University of Jyväskylä'sAcademy Research Fellow Matti Jalasvuori's research group 255 000 euro grant for investigating the conjugative transfer of anti-antibiotic resistance genetic elements.

12 Apr 2019

FDA approves new treatment for adults with metastatic bladder cancer

The U.S. Food and Drug Administration today granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy.

12 Apr 2019

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers have discovered a potential new way to treat chronic inflammatory diseases, by eliminating damaged mitochondria before they trigger excessive inflammation.

12 Apr 2019

Large-scale screen of mouse mutants reveals 38 new genes involved in hearing loss

A large-scale screen of mouse mutants has revealed multiple new genes involved in hearing loss, according to a study publishing April 11 in the open-access journal PLOS Biology by Karen Steel of King’s College London and the Wellcome Sanger Institute, and colleagues.

12 Apr 2019

Johns Hopkins scientists design new cell model of aging-associated colon cancer risk

Johns Hopkins Kimmel Cancer Center researchers say a new study of clusters of mouse cells known as "organoids" has significantly strengthened evidence that epigenetic changes, common to aging, play a essential role in colon cancer initiation.

12 Apr 2019

Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side.

12 Apr 2019

New technique uses UV and red light to decontaminate organs before transplantation

A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is described in an article published in the journal Nature Communications.

12 Apr 2019

NASA Twins Study: Extended spaceflight has small, transient effect on the gut microbiome

A year in space seems to have a small but significant, transient effect on the gut microbiome, according to a new paper on the NASA Twins Study published in the journal Science.

12 Apr 2019

High levels of blood lipids may worsen multiple sclerosis symptoms in obese patients

A newly published paper in the Lancet journal EBioMedicine identifies a link between high levels of blood lipids and worsening of disease in multiple sclerosis patients who are overweight or obese.

12 Apr 2019

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Two top researchers at the Ohio University Heritage College of Osteopathic Medicine are working with two other institutions on a federally funded project to investigate why Hispanics are more prone to develop non-alcoholic fatty liver disease.

12 Apr 2019

Researchers discover unique approach to treat some chronic inflammatory diseases

Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases.

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Rare gut condition is more predictable from individual's genetic makeup, study finds

Hirschsprung disease - a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool - is more predictable from an individual's genetic makeup than previously envisioned.

11 Apr 2019

Bacteria share genes with one another, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling - independent of their microbial hosts - from one part of the body to another, researchers report in the journal Scientific Reports.

11 Apr 2019

Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells.

11 Apr 2019

MUSC researchers find why some babies are born with malformed hearts

Almost one percent of all American babies are born with malformed hearts. Heart abnormalities are at once the most common and most deadly type of birth defect in the U.S.

11 Apr 2019

Genetic News and Research

Study finds ‘superbug’ in hands or nostrils of patients staying in the hospital

New genetic treatment removes antibiotic resistance from bacteria

FDA approves new treatment for adults with metastatic bladder cancer

Removing damaged mitochondria may relieve chronic inflammatory conditions

Large-scale screen of mouse mutants reveals 38 new genes involved in hearing loss

Johns Hopkins scientists design new cell model of aging-associated colon cancer risk

Researchers identify rare SRC-1 gene variants related to human obesity

New technique uses UV and red light to decontaminate organs before transplantation

NASA Twins Study: Extended spaceflight has small, transient effect on the gut microbiome

High levels of blood lipids may worsen multiple sclerosis symptoms in obese patients

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Researchers discover unique approach to treat some chronic inflammatory diseases

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Study describes vulnerability shared by large subset of cancer cell lines

Rare gut condition is more predictable from individual's genetic makeup, study finds

Bacteria share genes with one another, even across tissue boundaries

Researchers discover pathway contributing to fatty liver disease

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

Biochemical switches could be triggered to treat pathology of IBM, ALS and FTD

MUSC researchers find why some babies are born with malformed hearts

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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