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Nanocapsules packed with gene-editing tools could be promising platform for many gene therapies

New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body can be complicated and may cause troubling side effects.

10 Sep 2019

New oral splint can reduce tics in children and adults with Tourette syndrome

Tourette syndrome is a neurological disorder characterized by vocal and motor tics, which can contribute to anxiety, depression, and low self-esteem.

10 Sep 2019

Kessler Foundation scientists awarded NIH grant to study effects of post stroke robotic intervention

Karen Nolan, PhD, senior research scientist, and Soha Saleh, PhD, research scientist, in the Center for Mobility and Rehabilitation Engineering Research at Kessler Foundation, were awarded a $3,547,908 R01 grant by the National Institutes of Health.

10 Sep 2019

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

Many patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolve to fend off the treatment. Oncologists want to be able to quickly detect cancer drug resistance as it emerges in their patients and identify another drug the tumors will still respond to.

10 Sep 2019

Study looks at effects of Ritalin on children with ADHD

When children with ADHD don't respond well to Methylphenidate (MPH, also known as Ritalin) doctors often increase the dose.

9 Sep 2019

GABA neurons affect the circadian clock

Researchers from Graduate School of Medicine, Nagoya University, Hokkaido University Graduate School of Medicine and Gunma University Graduate School of Medicine have collaborated to uncover the role of GABA-ergic neurons or the inhibitory neurons in the functioning of the central circadian clock of the body.

9 Sep 2019

Prolonged opioid use linked to low testosterone

A new study has confirmed that a major effect of opioid overuse in adults is hypogonadism, or the abnormally low secretion of testosterone. This is associated with low sexual interest, loss of muscle and bone mass, increase in fatty tissue and infertility.

9 Sep 2019

Chronic hypertension among older pregnant women has spiked by more than 75% since 1970

The rate of chronic hypertension among pregnant women age 35 and over in the United States has increased by more than 75% since 1970, with black women suffering from persistent high blood pressure at more than twice the rate of white women, according to a Rutgers study.

9 Sep 2019

Millions of diabetes patients are missing out on Medicare’s nutrition help

Louis Rocco has lived with diabetes for decades but, until he met with a registered dietitian in August, he didn't know eating too much bread was dangerous for him.

9 Sep 2019

Rutgers study finds genetically tractable cause of drug-tolerant tuberculosis

A Rutgers New Jersey Medical School study has found a genetically tractable cause of drug tolerant tuberculosis, paving the way for researchers to develop new drugs to combat the global TB epidemic and cure the disease.

9 Sep 2019

Nanoparticles activated by X rays used to target deep tumours

A team of researchers from University of Texas at Arlington, University of Rhode Island and Brown University have collaborated to come up with use of nanoparticles in targeted therapy for deep seated cancers. Their success with the nanoparticples was published in a study titled, “X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors,” was published in the latest issue of the journal Proceedings of the National Academy of Sciences.

8 Sep 2019

Drug tolerant Tuberculosis could soon be tracked using genes

A team of researchers from the Rutgers New Jersey Medical School have found genetic foot prints of tuberculosis bacteria that are resistant to the commonly used anti-tubercular drugs. This could help scientists develop drugs to combat drug resistance in tuberculosis.

8 Sep 2019

Mobile apps improve atrial fibrillation detection rates in a low-risk population

A new study has shown that mobile health (mHealth) devices are able to screen for the common cardiac disorder called atrial fibrillation (AF).

8 Sep 2019

Akron professor receives NSF grant to help premature babies breathe

It's that sound we hear when healthy babies are born, just seconds after delivery -- a gasp of air, perhaps even a cry, as a newborn inflates its lungs for the very first time.

8 Sep 2019

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Recent clinical trials have indicated that immune checkpoint blockade (ICB) therapy, which is designed to unleash a patient's immune system to attack cancer, has been revolutionary in its implications for breast cancer treatment, especially for its potential to treat patients with triple negative breast cancer.

8 Sep 2019

Deep brain magnetic stimulation can improve symptoms of OCD

Researchers have found that focusing powerful non-invasive magnet stimulation on a specific brain area can improve the symptoms of Obsessive Compulsive Disorder.

8 Sep 2019

Study examines screening and treatment of opioid-induced low testosterone in men

Long-term opioid use previously has been linked with low testosterone in men. What has been unclear is how many men taking opioids had been screened or treated for low testosterone.

8 Sep 2019

Speech difficulties in five-year-old internationally adopted children with cleft palate

In a group of internationally adopted children with cleft lip and/or palate, speech at age five is impaired compared to a corresponding group of children born in Sweden, a study shows.

7 Sep 2019

Researchers explore how talk therapy can help cystic fibrosis patients with mental health problems

Drexel University researchers are exploring how Acceptance and Commitment Therapy, a type of talk therapy, delivered via telemedicine, may alleviate the anxiety and depression common among cystic fibrosis patients.

7 Sep 2019

FDA approves first drug to treat patients with rare lung condition

The U.S. Food and Drug Administration today approved Ofev (nintedanib) capsules to slow the rate of decline in pulmonary function in adults with interstitial lung disease associated with systemic sclerosis or scleroderma, called SSc-ILD. It is the first FDA-approved treatment for this rare lung condition.

7 Sep 2019

Therapy News and Research

Nanocapsules packed with gene-editing tools could be promising platform for many gene therapies

New oral splint can reduce tics in children and adults with Tourette syndrome

Kessler Foundation scientists awarded NIH grant to study effects of post stroke robotic intervention

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

Study looks at effects of Ritalin on children with ADHD

GABA neurons affect the circadian clock

Prolonged opioid use linked to low testosterone

Chronic hypertension among older pregnant women has spiked by more than 75% since 1970

Millions of diabetes patients are missing out on Medicare’s nutrition help

Rutgers study finds genetically tractable cause of drug-tolerant tuberculosis

Nanoparticles activated by X rays used to target deep tumours

Drug tolerant Tuberculosis could soon be tracked using genes

Mobile apps improve atrial fibrillation detection rates in a low-risk population

Akron professor receives NSF grant to help premature babies breathe

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Deep brain magnetic stimulation can improve symptoms of OCD

Study examines screening and treatment of opioid-induced low testosterone in men

Speech difficulties in five-year-old internationally adopted children with cleft palate

Researchers explore how talk therapy can help cystic fibrosis patients with mental health problems

FDA approves first drug to treat patients with rare lung condition

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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