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Large-scale genomic sequencing narrows search for Strep A vaccine

The global search for a group A streptococcal (Strep A) vaccine has narrowed after researchers identified a common gene signature in almost all global Strep A strains by sequencing thousands of genomes in a project spanning 10 years and more than 20 countries.

28 May 2019

Acute exposure to flavored e-liquids exacerbates endothelial cell dysfunction, study finds

There has been a rapid rise in e-cigarette use, but its health effects have not been well-studied and their effect on vascular health remains unknown.

28 May 2019

Children from disadvantaged backgrounds have lower levels of vigorous physical activity

Children from disadvantaged backgrounds and certain ethnic minority backgrounds, including from Pakistani and Bangladeshi backgrounds, have lower levels of vigorous physical activity, according to researchers at the University of Cambridge.

28 May 2019

Researchers get one step closer to global Strep A vaccine

The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2000 Group A Streptococcus samples from around the world.

27 May 2019

Mutations in 'junk' DNA can cause autism, study shows

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.

27 May 2019

Artificial intelligence technique identifies new class of mutations behind autism

Many mutations in DNA that contribute to disease are not in actual genes but instead lie in the 99% of the genome once considered "junk." Even though scientists have recently come to understand that these vast stretches of DNA do in fact play critical roles, deciphering these effects on a wide scale has been impossible until now.

27 May 2019

Investigating RNA-based regulation of the cardiovascular system

Goethe University and TU Munich have jointly obtained a new Collaborative Research Centre (Sonderforschungsbereich - SFB), which will receive approximately € 11 million in funding from the German Research Foundation over the next four years.

27 May 2019

Coming soon: New home blood-testing device for people with chronic illnesses

Université de Montréal's Laboratory of Biosensors & Nanomachines, in partnership with Montreal company Nanogenecs Diagnostics, has just been awarded a 700 000$ NSERC 'Idea to Innovation' grant to develop a home blood-testing device for people with chronic illnesses.

27 May 2019

Being overweight around age 18 linked with higher risk of cardiomyopathy in adulthood

A large study of Swedish men found that those who were even mildly overweight around age 18 were more likely develop cardiomyopathy in adulthood -- an uncommon heart muscle condition that can cause heart failure, according to new research in the American Heart Association's journal Circulation.

27 May 2019

Drug therapy for stable heart failure patients can be simplified by stopping diuretics

Drug therapy for patients with stable heart failure can be simplified by stopping diuretics, according to late-breaking results from the ReBIC-1 trial presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

27 May 2019

NYU Langone vascular surgeon's discovery saves Brooklyn man's foot

When Jose Palacios arrived to the operating room at NYU Langone Hospital–Brooklyn last March, he thought he might never walk again. The infection in his foot had gotten so bad his doctor told him amputation may be necessary. But when the surgery was over, he could hardly believe his eyes.

26 May 2019

Weekly pharmacy visits improve drug adherence and quality of life in elderly patients with heart failure

Elderly patients with heart failure who see a pharmacist once a week are more likely to take their tablets and be active in daily life, according to late breaking results from the PHARM-CHF randomized controlled trial presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

26 May 2019

Biomarkers help tailor diuretic treatment for acute heart failure patients

Adrenomedullin activity predicts which acute heart failure patients are at the greatest risk of death without diuretic treatment post-discharge, according to late breaking research presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

26 May 2019

Mobile phone app may help boost and maintain physical activity in women

Activity trackers and mobile phone apps are all the rage, but do they really help users increase and maintain physical activity?

25 May 2019

Researchers develop new algorithm to accurately predict patients' chances of survival in ICU

Researchers from the University of Copenhagen and Rigshospitalet have used data on more than 230,000 intensive care patients to develop a new algorithm.

25 May 2019

Deactivating specific protein with drugs reverses inflammation, scarring of liver in NASH patients

A team of researchers led by Duke-NUS Medical School and National Heart Centre Singapore found that deactivating a specific protein - interleukin 11 - with drugs called therapeutic antibodies, reverses inflammation and scarring of the liver in patients suffering from an untreatable type of fatty liver disease called non-alcoholic steatohepatitis .

25 May 2019

New statement emphasizes need for special multidisciplinary clinical programs

With a better understanding of how various heart conditions are inherited, and the availability of faster and less expensive genetic testing, there is need for more specialized multidisciplinary clinical programs that combine focused expertise in heart disease and genetics, according to a new statement from the American Heart Association, the world's leading voluntary organization focused on heart and brain health.

25 May 2019

Heart News and Research

Large-scale genomic sequencing narrows search for Strep A vaccine

Acute exposure to flavored e-liquids exacerbates endothelial cell dysfunction, study finds

Children from disadvantaged backgrounds have lower levels of vigorous physical activity

Researchers get one step closer to global Strep A vaccine

Mutations in 'junk' DNA can cause autism, study shows

Artificial intelligence technique identifies new class of mutations behind autism

Investigating RNA-based regulation of the cardiovascular system

Coming soon: New home blood-testing device for people with chronic illnesses

Being overweight around age 18 linked with higher risk of cardiomyopathy in adulthood

Drug therapy for stable heart failure patients can be simplified by stopping diuretics

NYU Langone vascular surgeon's discovery saves Brooklyn man's foot

Weekly pharmacy visits improve drug adherence and quality of life in elderly patients with heart failure

Biomarkers help tailor diuretic treatment for acute heart failure patients

Mobile phone app may help boost and maintain physical activity in women

Researchers develop new algorithm to accurately predict patients' chances of survival in ICU

Deactivating specific protein with drugs reverses inflammation, scarring of liver in NASH patients

New statement emphasizes need for special multidisciplinary clinical programs

Project promotes dialogue and participation in Alzheimer's research

High-intensity interval training may improve heart function in adults with type 2 diabetes

Simple test can easily measure common stress hormones

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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