Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Bone marrow-derived fibroblasts shown to promote breast cancer growth

A new study has revealed that breast cancer cells recruit bone marrow-derived fibroblasts to enhance their growth.

23 Nov 2018

FDA approves new treatment for AML patients

The U.S. Food and Drug Administration today approved Daurismo (glasdegib) tablets to be used in combination with low-dose cytarabine (LDAC), a type of chemotherapy, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are 75 years of age or older or who have other chronic health conditions or diseases (comorbidities) that may preclude the use of intensive chemotherapy.

22 Nov 2018

Blocking activity of plasma protein can be possible way to protect against radiation-induced injury

It is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma protein during and immediately after radiation, the patient can be protected against injury. This is shown in a new doctoral thesis at Umeå University, Sweden.

20 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

Infant gut microbes altered by mother's obesity may increase risk for future disease

Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.

16 Nov 2018

Treating children with 'bubble baby disease'

An international study published in the journal Blood by researchers led by Dr. Elie Haddad, a pediatric immunologist and researcher at CHU Sainte-Justine and professor at Université de Montréal, highlights the urgent need to develop better treatment strategies for patients suffering from severe combined immune deficiency.

15 Nov 2018

Scientists harness power of natural killer cells to treat children with neuroblastoma

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer (NK) cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies.

14 Nov 2018

Study sheds light on mechanisms that prevent autoimmune attack

Understanding the mechanisms that prevent our immune system damaging healthy cells, whilst fighting infection and cancer, could lead to the development of novel immune-regulating treatments.

14 Nov 2018

Survey: Majority of Americans are concerned about health threat posed by antibiotic resistance

Nearly two thirds of Americans (65%) say antibiotic resistance is a public health problem and a strong majority (81%) say they are concerned that antibiotic resistance will make more infections difficult or impossible to treat and even deadly, according to a national public opinion survey commissioned by Research!America in collaboration with the Infectious Disease Society of America.

13 Nov 2018

Cancer stem cells depend on amino acid metabolism, and it's proving to be their Achilles' heel

Think of energy metabolism like a party popper: Ripping something apart releases a bang. Most of your cells rip apart sugar to release the "bang" of energy. Sometimes they rip apart fats, and in a pinch, cells can even metabolize protein.

13 Nov 2018

Study shows novel strategy to reduce breast cancer bone metastasis

Uncovering a novel mechanism that promotes growth of breast cancer bone metastasis has revealed a potential Achilles' heel for these cancer cells. Reported in the journal Cancer Cell, the study shows that interfering with this mechanism can reduce the risk of relapses in animal models.

12 Nov 2018

Researchers create new accessible staging system to predict survival for patients with AL amyloidosis

A new staging system developed with a more accessible test to predict the chance of survival in patients living with light chain (AL) amyloidosis.

8 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute, have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

5 Nov 2018

PPM1D gene confers a survival advantage to stem cells after chemotherapy

Chemotherapy has been associated with increased risk of leukemia years after the treatment, but what leads to that association is not clear.

2 Nov 2018

Researchers uncover link between RNA abnormalities and multiple myeloma progression

Multiple myeloma is the second most common type of blood cancer where cancer cells accumulate in the bone marrow, crowding out healthy blood cells.

1 Nov 2018

New study to evaluate human immune system's response to influenza

The key to lasting protection against influenza may be in your bones. The cells that naturally protect you against illness originate and live in your bone marrow - and that is one spot where scientists will be looking to understand the human immune system's response to influenza in a groundbreaking new study led by the Human Vaccines Project.

1 Nov 2018

High blood pressure caused by specific signaling from the brain promotes heart disease

About 6 million Australians aged 18 years and over have high blood pressure. Of these, more than two thirds had uncontrolled or unmanaged high blood pressure (not taking medication), representing 4 million adult Australians.

1 Nov 2018

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins.

31 Oct 2018

Bone Marrow News and Research

Further Reading

Bone marrow-derived fibroblasts shown to promote breast cancer growth

FDA approves new treatment for AML patients

Blocking activity of plasma protein can be possible way to protect against radiation-induced injury

Scientists equip new virus that kills carcinoma cells with protein

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Infant gut microbes altered by mother's obesity may increase risk for future disease

Treating children with 'bubble baby disease'

Scientists harness power of natural killer cells to treat children with neuroblastoma

Study sheds light on mechanisms that prevent autoimmune attack

Survey: Majority of Americans are concerned about health threat posed by antibiotic resistance

Cancer stem cells depend on amino acid metabolism, and it's proving to be their Achilles' heel

Study shows novel strategy to reduce breast cancer bone metastasis

Researchers create new accessible staging system to predict survival for patients with AL amyloidosis

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

PPM1D gene confers a survival advantage to stem cells after chemotherapy

Researchers uncover link between RNA abnormalities and multiple myeloma progression

New study to evaluate human immune system's response to influenza

High blood pressure caused by specific signaling from the brain promotes heart disease

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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