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Stem cells appear to play a role in repairing organs

Not least because undifferentiated cells with features typical of stem cells are being increasingly found in organs like the liver, brain, and muscles, scientists are beginning to assume that these cells play a role in repairing organs.

3 Nov 2005

New way to generate genetically altered influenza virus

In the event of an influenza pandemic, the world's vaccine manufacturers will be in a race against time to forestall calamity.

1 Nov 2005

Chiron initiates Phase I/II study of an investigational cell culture-derived influenza vaccine

Cell culture-derived influenza vaccine (commonly referred to as "flu cell culture" vaccine) represents the next generation of influenza vaccine, both for annual vaccine production and for long-term pandemic preparedness.

26 Oct 2005

Study of the molecular mechanism involved in the human implantation process

In spite of advances in assisted reproductive technologies, more than 6.1 million women in the United States - roughly 20 percent of all women of reproductive age - suffer from infertility.

17 Oct 2005

New treatment for the pediatric eye cancer retinoblastoma

Investigators at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer retinoblastoma that appears to be more effective than the current standard therapy, and more likely to prevent the recurrence of this cancer. A report on their work appears in the October 15 issue of Clinical Cancer Research.

17 Oct 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Transplantation of insulin-producing pancreatic beta-cells shows great promise as a treatment for type 1 diabetes, but development of this therapy has been hampered by a severe shortage of donor beta-cells, which are obtained from decreased human donors.

26 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

Prostate cancer manipulates an important group of signaling proteins called Wnts to establish itself in bone

Prostate cancer is a cruel disease. Left untreated, prostate cancer cells often metastasize, or spread, to bone where they form fracture-prone tumors that are extremely painful.

1 Sep 2005

New technique for creating human embryonic stem cells

Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem cells. The fusion causes the adult cells to undergo genetic reprogramming, which results in cells that have the developmental characteristics of human embryonic stem cells.

22 Aug 2005

Researchers have identified a pathway that is specific for cancer

When cancer spreads, people often die. That's why a lot of cancer research and drugs focus on the metabolic pathways that allow cancer to metastasize -- to spread from one part of the body to another.

1 Aug 2005

Experimental treatment shown to reverse the loss of nerve fibres in Parkinson's Disease

Analysis of the brain of a patient suffering from Parkinson's Disease has shown that the experimental treatment he received caused regrowth of the nerve fibres that are lost in this disease. The findings are reported in the July issue of Nature Medicine.

6 Jul 2005

Experimental treatment regrows nerve fibres in patient suffering Parkinson's disease

Analysis of the brain of a patient suffering from Parkinson’s Disease has shown that the experimental treatment he received caused regrowth of the nerve fibres that are lost in this disease. The findings are reported in the July issue of Nature Medicine.

30 Jun 2005

Omega-3 combined with propofol may lead to new drugs to treat breast cancer

Omega-3, the fatty acid found in oily fish, could be combined with a commonly used anesthetic to develop drugs to treat breast cancer, according to research published in the journal Breast Cancer Research.

8 Jun 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

Premature use of stem cell therapy could put patients at risk

The premature use of stem cell therapy could put many patients at risk of viral or prion diseases unless appropriate safety systems are in place, warn experts in this week’s BMJ.

19 May 2005

Black cohosh may interfere with breast cancer drugs

Black cohosh, an herb widely used by breast cancer patients to alleviate hot flashes and other menopausal symptoms, may alter the way that cells respond to drugs commonly used to treat breast cancer, according to a Yale School of Medicine study in Breast Cancer Research and Treatment.

27 Apr 2005

Guidelines for research involving human embryonic stem cells

The National Academies today recommended guidelines for research involving human embryonic stem cells, and urged all institutions conducting such research to establish oversight committees to ensure that the new guidelines will be followed.

26 Apr 2005

Cell Line News and Research

Stem cells appear to play a role in repairing organs

New way to generate genetically altered influenza virus

Chiron initiates Phase I/II study of an investigational cell culture-derived influenza vaccine

Study of the molecular mechanism involved in the human implantation process

New treatment for the pediatric eye cancer retinoblastoma

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Human embryonic stem cell lines accumulate changes in their genetic material over time

Human embryonic stem cell lines accumulate changes in their genetic material over time

Prostate cancer manipulates an important group of signaling proteins called Wnts to establish itself in bone

New technique for creating human embryonic stem cells

Researchers have identified a pathway that is specific for cancer

Experimental treatment shown to reverse the loss of nerve fibres in Parkinson's Disease

Experimental treatment regrows nerve fibres in patient suffering Parkinson's disease

Omega-3 combined with propofol may lead to new drugs to treat breast cancer

Researchers generate patient-specific stem cells

Premature use of stem cell therapy could put patients at risk

Black cohosh may interfere with breast cancer drugs

Guidelines for research involving human embryonic stem cells

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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