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Study highlights variable use and rising costs of antivirals in treating pediatric influenza in the U.S.

The Pediatrics study analyzes trends in antiviral usage among U.S. children and adolescents with influenza, revealing significant variations in dispensing rates and costs, and low usage among children under six years, emphasizing the need for improved treatment strategies.

16 Nov 2023

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Two landmark clinical trials reported today at the Union meeting showed that an oral antibiotic taken for six months once-daily substantially reduced the risk of developing drug-resistant TB.

16 Nov 2023

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

An interview with Dr Beverley Isherwood.

16 Nov 2023

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

The effectiveness of herbs and alternative medicines in preventing liver injury induced by anti-tuberculosis (anti-TB) drugs.

16 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Oral nicotine pouches fail to satisfy cravings of current smokers

Oral nicotine pouches, a tobacco-leaf-free product marketed as an alternative to cigarettes, do little to curb current smokers' nicotine cravings, according to a new study.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

Review sheds light on the complex challenge of diagnosing and managing cow's milk allergy in children

The Nutrients journal review highlights the challenges in diagnosing and managing Cow's Milk Allergy (CMA) in children, emphasizing the discrepancy between clinical guidelines and actual practice, and the need for improved strategies in prevention and management.

14 Nov 2023

UK soft drinks levy may have reduced tooth extractions in children by 12%, study finds

The UK soft drinks industry levy introduced in 2018 may have reduced the number of under 18s having a tooth removed due to tooth decay by 12%, suggests research published in the open access journal BMJ Nutrition, Prevention & Health.

14 Nov 2023

Researchers identify the role of iron in ocular toxoplasmosis

Researchers from Nagoya University Graduate School of Medicine have identified the role of iron in ocular toxoplasmosis (OT), a form of toxoplasmosis that causes blindness.

14 Nov 2023

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Cannabidiol (CBD) is marketed by some suppliers as a painkiller, e.g. for osteoarthritis of the knee. Animal experiments have shown that the substance, which is extracted from the hemp plant, has an anti-inflammatory and pain-relieving effect in arthritis.

14 Nov 2023

Neural circuits respond to rapid dopamine surges

Researchers assess the pharmacodynamics of dopamine signaling, brain connectivity/activity, and self-documented 'high' following methylphenidate exposure.v

14 Nov 2023

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20 percent of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2 percent of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Study reveals underuse of antiviral medications in young children with influenza

Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a new study reports an underuse of the treatment.

13 Nov 2023

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

In this study, researchers compared the effectiveness of sports drinks with varying carbohydrate and sodium levels for rehydrating athletes post-exercise, finding that drinks with higher sodium and lower carbohydrate content were more effective for rapid and complete rehydration. The study highlighted the importance of beverage composition in athlete recovery and hydration strategies.

13 Nov 2023

Major trial finds apixaban reduces stroke risk in patients with device-detected atrial fibrillation

The widely available blood thinner apixaban substantially reduced stroke in at-risk patients with a type of atrial fibrillation only detectable by a pacemaker or other implanted cardiac electronic device, a global study has found.

13 Nov 2023

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

An experimental anti-clotting medication, abelacimab, significantly reduced bleeding among people with atrial fibrillation (or AFib) who were at risk of stroke, according to results of the AZALEA-TIMI 71 trial, presented today as late-breaking science at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

Oral News and Research

Study highlights variable use and rising costs of antivirals in treating pediatric influenza in the U.S.

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Oral nicotine pouches fail to satisfy cravings of current smokers

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Review sheds light on the complex challenge of diagnosing and managing cow's milk allergy in children

UK soft drinks levy may have reduced tooth extractions in children by 12%, study finds

Researchers identify the role of iron in ocular toxoplasmosis

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Neural circuits respond to rapid dopamine surges

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Study reveals underuse of antiviral medications in young children with influenza

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

Major trial finds apixaban reduces stroke risk in patients with device-detected atrial fibrillation

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

UK regulator approves a diabetes drug for weight management in obese and overweight patients

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