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Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, scientists must first precisely understand on the cellular and molecular levels which factors are necessary for implanted stem-cell derived heart cells to properly grow and integrate in three dimensions within surrounding tissue.

8 Mar 2023

Does ingested fluoride affect the human microbiome?

Researchers discuss the effect(s) of fluoride exposure on the human microbiome.

7 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer.

7 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

First-in-woman study of a non-hormonal vaginal film showed safety, potential contraceptive efficacy, and supports future development

Researchers developed a novel contraceptive 'ZB-06' a vaginal film containing a human contraceptive antibody called HC4-N that agglutinates sperm.

7 Mar 2023

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Researchers characterized serological neutralizing antibody responses to norovirus among young children, transitioning between sequential GII.4 pandemic strains, DH 2006, NO 2009, and SY 2012.

3 Mar 2023

Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

Researchers observe corneal damage by blue light exposure is due to PI3K/AKT pathway inhibition.

1 Mar 2023

Product development and drug delivery at Seda

In this interview, NewsMedical speaks with Shanoo about her career progression and role in Seda Pharmaceutical regarding product development and drug delivery. She also outlines some of the services that Seda offers.

From Seda Pharmaceutical Development Services 1 Mar 2023

Five Alarm Bio, Focused on Minimising the Effects of Aging in Humans, Raises Seed Investment

Investors include Cambridge Angels, Meltwind, o2h Ventures, SyndicateRoom, and Angel investors, with support from KPMG Acceleris.

From Five Alarm Bio 28 Feb 2023

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System.

From CN Bio 28 Feb 2023

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Novel microfluidic model mimics a rare genetic disorder

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

24 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

Organoid models for research on Chinese herbal medicine

Announcing a new publication for Acta Materia Medica journal. Organoids are three-dimensional cell accusations generated from pluripotent stem cells or adult stem cells in vitro.

24 Feb 2023

Technology-assisted pregnancies increase the likelihood of preeclampsia

People who became pregnant using assisted reproductive technologies were found to be over twice as likely to develop preeclampsia than those with traditional pregnancies, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

in vitro News and Research

Study creates a radical new view of how immune cells recognize threats

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Does ingested fluoride affect the human microbiome?

How gut microbiota control feelings of fullness after eating

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

First-in-woman study of a non-hormonal vaginal film showed safety, potential contraceptive efficacy, and supports future development

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

Product development and drug delivery at Seda

Five Alarm Bio, Focused on Minimising the Effects of Aging in Humans, Raises Seed Investment

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Novel microfluidic model mimics a rare genetic disorder

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

Organoid models for research on Chinese herbal medicine

Technology-assisted pregnancies increase the likelihood of preeclampsia

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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