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Combination therapy for rheumatoid arthritis may lead to higher remission rates

Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may see less disease activity and higher remission rates after biologic therapy plus methotrexate (MTX) rather than either treatment alone.

22 Aug 2019

KHN’s ‘What the Health?’: All about Medicare

Before "Medicare for All," there was just Medicare, the very popular program that serves 60 million Americans age 65 and older or younger people with certain disabilities.

22 Aug 2019

New study reveals exosome-mediated communication between mother and baby

During pregnancy, the mother and the baby communicate in a variety of ways. For instance, signals from the fetus are crucially involved in the initiation of labor and delivery.

22 Aug 2019

Computer model could be used to quickly evaluate new drugs for sickle cell disease

A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease.

22 Aug 2019

New model developed to optimize and personalize radiotherapy for cancer patients

A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with specific mutations or patterns.

22 Aug 2019

Ludwig study uncovers novel vulnerability in MYC-driven cancers

A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the cell's machinery for making fats and other lipids.

22 Aug 2019

New therapy found to be effective for patients with a particular type of bone marrow cancer

Mount Sinai researchers have found a new type of therapy to be effective for patients with a particular type of bone marrow cancer that is resistant to several standard therapies, according to results of a clinical trial published in The New England Journal of Medicine in August.

22 Aug 2019

Enzyme induced by stress associated with liver cancer growth

An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer to thrive, scientists report.

22 Aug 2019

Single course of antibiotics may boost colon cancer risk

In an extensive "data mining" analysis of British medical records, researchers at the Johns Hopkins Kimmel Cancer Center conclude that taking even a single course of antibiotics might boost--albeit slightly--the risk of developing colon cancer--but not rectal cancer--a decade later.

22 Aug 2019

Shopping abroad for cheaper medication? Here’s what you need to know

In its effort to temper the sky-high prices Americans pay for many vital medications, the Trump administration last month unveiled a plan that would legalize the importation of selected prescription drugs from countries where they sell for far less.

22 Aug 2019

Study uncovers cause of asthmatic lung spasms

Researchers at Rutgers and other institutions have discovered how muscle contraction (bronchospasm) in the airway, which cause breathing difficulty in people with asthma, occur by creating a microdevice that mimics the behavior of the human airways.

22 Aug 2019

New insights into protein transport could help define strategies for treating eye disease

Many forms of vision loss stem from a common source: impaired communication between the eye and the brain. And at the root of all eye-to-brain communication are the hundreds of proteins generated by the retina's nerve cells.

22 Aug 2019

'Kissing loops' in lncRNA essential for tumor suppressor function

Human cells - like those of many other organisms - have developed mechanisms to protect us from cancer.

22 Aug 2019

UC San Diego researchers identify new therapeutic approach to kill cancer cells

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic.

22 Aug 2019

Study opens up a new way for developing potential glioblastoma treatment

A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer.

22 Aug 2019

Researchers unlock mysteries surrounding maternal/fetal cellular communication during pregnancy

Researchers have unlocked mysteries surrounding how a pregnant mother's cells and her fetus' cells communicate throughout pregnancy.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019