Genes News and Research

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Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.

7 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

Mitochondria essential for cellular ageing

An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.

5 Feb 2016

NIH researchers identify genetic mutation responsible for vibratory urticaria

Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration, also known as vibratory urticaria. Running, hand clapping, towel drying or even taking a bumpy bus ride can cause temporary skin rashes in people with this rare disorder.

4 Feb 2016

Duke researchers identify promising target for renal cell carcinomas

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread.

4 Feb 2016

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

Carnegie Mellon University is embarking on a five-year, $12 million research effort to reverse-engineer the brain, seeking to unlock the secrets of neural circuitry and the brain's learning methods. Researchers will use these insights to make computers think more like humans.

4 Feb 2016

New research identifies key enzyme linked to age-related increases in cancer and inflammation

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

4 Feb 2016

Genetic variants associated with preference to mornings or nights

23andMe, Inc., the leading personal genetics company, today announced the results of a genome-wide association study (GWAS) identifying genetic variants associated with being a morning person.

3 Feb 2016

UCI researchers identify potential strategies to prevent cognitive decline

As brain cells age they lose the fibers that receive neural impulses, a change that may underlie cognitive decline. Researchers at the University of California, Irvine recently found a way to reverse this process in rats. The study was published February 3 in The Journal of Neuroscience. Researchers caution that more studies are needed, but the findings shed light on the mechanisms of cognitive decline and identify potential strategies to stem it.

3 Feb 2016

'Housekeeping' gene may have a link to male infertility

Researchers at Iowa State University have found evidence that a "housekeeping" gene present in every cell of the body may have a link to male infertility.

3 Feb 2016

Prenatal stress affects babies' health in war-torn areas

Children from war-torn areas of the globe are affected by trauma even before they are born, according to a new University of Florida study.

3 Feb 2016

Seafood consumption may benefit older adults at risk for Alzheimer's disease

New research published Feb. 2 in the Journal of the American Medical Association found that older adults with a major risk gene for Alzheimer's disease known as APOE?4 who ate at least one seafood serving per week showed fewer signs of Alzheimer's-related brain changes. In contrast, this association was not found in the brains of volunteers who ate fish weekly but did not carry the risk gene.

3 Feb 2016

Study sheds light on mechanisms linked to formation of healthy egg cells in humans

Congenital disorders such as Down's syndrome could be better understood, following new insights into how healthy cells are formed.

3 Feb 2016

Researchers identify new targets that may help prevent and cure colon cancer

When the audio on your television set or smart phone is too loud, you simply turn down the volume. What if we could do the same for the signaling in our bodies that essentially causes normal cells to turn cancerous? New discoveries by researchers at the Stephenson Cancer Center at the University of Oklahoma may point to new ways to do just that.

3 Feb 2016

Study finds no evidence of genetic overlap between schizophrenia risk and subcortical brain volumes

Over the last decade, important contributions to our understanding of schizophrenia have come from two different types of studies. Neuroimaging studies have found that certain parts of the brain, such as the hippocampus and amygdala, are smaller in people with schizophrenia - a devastating psychiatric illness with high heritability.

3 Feb 2016

Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

Successful reprogramming of muscle cells derived from biopsies of patients with Andersen's syndrome (AS) led to the formation of induced pluripotent stem (iPS) cells that can serve as a valuable model for understanding the cause of this rare disorder and discovering novel therapies.

3 Feb 2016

New approach to investigate how neurodevelopment influences diseases in adulthood

The Research Training Group, which builds on translational research training programmes and research structures such as the Molecular Medicine degree programme and the Interdisciplinary Centre for Clinical Research, will work on areas where basic research and clinical practice overlap. It will bring together 20 doctoral candidates from the natural sciences and 28 from medicine.

3 Feb 2016

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.

3 Feb 2016

UAB research explores neurofibromatosis type 1

It is easy to tell a medical research story that has a simple and dramatic moment. But disease is often much more complex, and the work to understand it can be painstaking. A vivid example of that is seen in the University of Alabama at Birmingham Medical Genomics Laboratory, headed by Ludwine Messiaen, Ph.D., professor of genetics. This lab offers clinical genetic testing for a broad array of common and rare genetic disorders.

3 Feb 2016

Genes News and Research

Aggression influences new nerve cell production in the brain

UIC researchers discover molecular switch that allows salmonella bacteria to fight immune system

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Mitochondria essential for cellular ageing

NIH researchers identify genetic mutation responsible for vibratory urticaria

Duke researchers identify promising target for renal cell carcinomas

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

New research identifies key enzyme linked to age-related increases in cancer and inflammation

Genetic variants associated with preference to mornings or nights

UCI researchers identify potential strategies to prevent cognitive decline

'Housekeeping' gene may have a link to male infertility

Prenatal stress affects babies' health in war-torn areas

Seafood consumption may benefit older adults at risk for Alzheimer's disease

Study sheds light on mechanisms linked to formation of healthy egg cells in humans

Researchers identify new targets that may help prevent and cure colon cancer

Study finds no evidence of genetic overlap between schizophrenia risk and subcortical brain volumes

Pluripotent stem cells could serve as valuable model for understanding Andersen's syndrome

New approach to investigate how neurodevelopment influences diseases in adulthood

New gene cut-and-paste methods help correct disease-causing mutation in animal model

UAB research explores neurofibromatosis type 1

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