Seafood consumption may benefit older adults at risk for Alzheimer's disease

New research published Feb. 2 in the Journal of the American Medical Association found that older adults with a major risk gene for Alzheimer's disease known as APOE-ε4 who ate at least one seafood serving per week showed fewer signs of Alzheimer's-related brain changes. In contrast, this association was not found in the brains of volunteers who ate fish weekly but did not carry the risk gene.

The researchers also examined the brains for levels of mercury, which can be found in seafood and is known to be harmful to the brain and nervous system. They found that seafood consumption was associated with increased mercury levels in the brains but not the amount of beta amyloid protein plaques and tau protein tangles, the hallmarks of Alzheimer's disease.