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High-fat diets in mouse parents alter offspring brain development

Researchers fed breeding pairs of mice five diets with different fat and sugar contents to examine how parental nutrition affects offspring brain development. High-fat diets, alone or combined with high sugar, delayed early motor development and altered brain structure in young adult offspring, while the high-sugar-only diet produced no significant changes in individual brain regions after correction for multiple comparisons.

28 Oct 2026

UCSF scientists develop smart CAR-T cells to fight childhood brain tumors

Scientists at UC San Francisco have engineered CAR-T cells that stay dormant until they reach the brain, where they switch on and destroy tumor cells.

28 Oct 2026

Inflammatory macrophages identified as drivers of chronic joint osteoarthritis

Researchers have identified a group of inflammatory macrophages that drive osteoarthritis by sustaining inflammation in the synovium – a layer of connective tissue within joints – and show that they can target these immune cells to treat the disease in mice.

28 Oct 2026

Researchers identify protein that drives chronic inflammation in psoriasis

In new preclinical studies, researchers have identified a protein that propels a vicious cycle of skin inflammation in psoriasis.

28 Oct 2026

Human challenge study reveals how preexisting immunity affects dengue

Dengue virus is especially pernicious compared with many other viruses, as secondary infections can actually be worse than the first one.

28 Oct 2026

Dual-targeting antibody successfully tackles multiple tumor types in mice

A novel antibody therapy empowers the immune system's tumor-fighting capabilities in mice by targeting immune-suppressing T cells with greater precision than previous approaches, according to new work.

28 Oct 2026

University of Utah researchers discover backup energy system in the heart

The heart is the hardest-working muscle in the body, beating constantly no matter what the body's energy reserves look like.

28 Oct 2026

Mindfulness-based behavioral therapy changes brain responses to reduce opioid cravings

Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral therapy used alongside medication treatment, may help people with opioid use disorder respond differently to drug-related cues and natural rewards, according to a randomized clinical trial led by researchers at the Icahn School of Medicine at Mount Sinai.

28 Oct 2026

Brain development eliminates flawed neurons to ensure genomic integrity

During fetal development, the human brain generates an excess of neurons, most of which are eliminated shortly before and after birth.

28 Oct 2026

Prefrontal cortex activity fails to predict individual emotion regulation

A supervisor criticizes a report in front of the entire team – you feel exposed and hurt. But if you tell yourself, "She takes my work seriously and wants the project to succeed," the same situation can lose some of its intensity. In psychology, this deliberate reinterpretation is called cognitive reappraisal.

28 Oct 2026

Study identifies common mechanism behind widespread cancer mutations

A family of mutations seen in about 20% of human cancers drives malignancy by changing the accessibility of genes to a particular regulatory protein, according to a study by Weill Cornell Medicine investigators.

28 Oct 2026

Japan's new law advances reproductive genome editing governance

A Hiroshima University researcher outlines advantages of Japan's new law that prohibits the transfer of genome-edited human embryos or germ cells into the human reproductive tract and imposes criminal penalties for violations.

28 Oct 2026

Engineered albumin could lead to needle-free, long-lasting protein medicines

Protein-based medicines have transformed the treatment of many diseases, but they often come with a limitation: they must be injected, sometimes repeatedly, because they are rapidly cleared from the bloodstream.

28 Oct 2026

Plant and animal proteins show opposite effects on testosterone levels

Higher animal protein intake was associated with lower blood testosterone levels, while higher plant protein intake was associated with higher levels, according to a new study from the University of Eastern Finland.

28 Oct 2026

DEBRA research invests in Topadur to advance small-molecule therapies for dystrophic Epidermolysis bullosa

DEBRA Research gGmbH, a global non-profit organization dedicated to advancing research and drug development for Epidermolysis bullosa (EB), and Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced an investment by DEBRA Research in Topadur to support a preclinical program exploring a new treatment approach for dystrophic Epidermolysis bullosa (DEB). DEB is one of the more severe forms of EB, characterized by extremely fragile skin and progressive, debilitating complications.

28 Oct 2026

Adalvo expands biosimilars portfolio through acquisition of romiplostim biosimilar program from Enzene

Adalvo today announced the acquisition of a romiplostim biosimilar program referencing Nplate® from Enzene, strengthening its biosimilars portfolio and accelerating the company’s expansion into complex biological medicines.

From Adalvo 28 Oct 2026

Prolific announces major new investments and partnerships with NantWorks and Zylidac Bio CDMO

On the heels of our exciting major investment and Nantworks partnership announcement last week, Prolific Machines is pleased to announce a great new partnership with Zylidac Bio, a fully integrated biologics CDMO located next door to us in San Francisco Bay Area, to scale up the production of Prolific's Optogentics-enabled cell lines for clinical and GMP manufacturing!

From Prolific Machines, Inc. 28 Oct 2026

Atelerix and Frontier Space partner to enable biological sample preservation for space missions

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced a partnership with Frontier Space, a UK based space biotechnology company building platform technology for in-orbit R&D and biomanufacturing.

From Atelerix Ltd 28 Oct 2026

Novel peptide from red alga shows potential for blood glucose control

It is a dietary staple found in sushi, rice wraps, and ramen toppings. Commonly known as nori in Japan and gim in Korea, red seaweed is especially popular across Asia.

27 Oct 2026

Early neurological deterioration affects 30% of awake craniotomy patients

A retrospective study of 30 patients undergoing awake craniotomy found that 30% experienced new or worsened neurological dysfunction within 48-72 hours after surgery. Early functional and cognitive score reductions were common, while new-onset aphasia occurred in 10% of patients.

27 Oct 2026