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Beyond ‘bad’ cholesterol: new clues to the risk of heart disease

Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level.

13 Oct 2026

Undecimal Bio launches with $18 million oversubscribed seed financing to address ‘liver trap’ in siRNA therapeutic delivery

Undecimal Bio, a platform biotechnology company advancing targeted delivery of siRNA therapeutics, today announced an oversubscribed $18 million USD seed financing.

From UndecimalBio 13 Oct 2026

Mursla Bio publishes peer-reviewed validation of tissue-specific extracellular vesicle platform for liquid biopsy

Mursla Bio, a precision medicine and diagnostics company built on tissue-specific extracellular vesicles (TS-EVs), today announced publication of a peer-reviewed study in the Journal of Extracellular Vesicles (impact factor 21.7), the founding journal of the International Society for Extracellular Vesicles. This validates the TS-EV platform for a new class of liquid biopsy: the multiomic disease biology of living cells in a chosen tissue, read from blood, starting with the liver.

From Mursla Bio 13 Oct 2026

Gene therapy and special goggles help some blind adults detect objects again

In a phase 1 study of 10 adults with advanced retinitis pigmentosa, researchers found that optogenetic gene therapy combined with light-stimulating goggles was generally well tolerated, although one participant experienced a severe but transient ocular adverse event. Seven participants showed improved light sensitivity, while four of eight who completed behavioral testing demonstrated modest gains in visual function, providing preliminary evidence of partial vision restoration that requires confirmation in larger controlled trials.

12 Oct 2026

Scientists pinpoint key hotspot driving tau propagation in dementia

Diseases such as Alzheimer's and frontotemporal dementia are considered neurodegenerative tauopathies, in which tau proteins in the brain misfold and lead to cognitive decline.

12 Oct 2026

Your favorite song might make a needle prick hurt less

A study of 204 patients undergoing intravenous cannulation before MRI found that those listening to their favorite music reported significantly lower pain scores than patients hearing no music at 30 seconds and two minutes after puncture. Mozart was also associated with lower pain scores among patients with pre-existing pain, while relaxation music showed no significant benefit, although the non-randomized findings require confirmation.

12 Oct 2026

Study finds a surprising downside to having favourite foods

In a study of 279 adults, researchers found that initially reinforcing existing food preferences reduced learning flexibility when associations between foods and outcomes changed. Participants learned positive associations more readily than negative ones, while associations involving disliked foods were more adaptable than those involving liked foods.

12 Oct 2026

Who moves first at night, you or your dog?

Researchers monitored 25 adults and 38 dogs and found no significant association between bedsharing and objectively measured human sleep duration or efficiency, although owners of multiple dogs reported poorer sleep quality in an analysis requiring cautious interpretation. Human and dog movements were positively correlated, with human activity more often preceding canine activity among pairs with identifiable associations, although the study could not determine which species drove the other's movements.

12 Oct 2026

Lifelong blindness enhances brain processing for better pitch discrimination

Are people who have been blind for most of their lives better at hearing than sighted individuals? New in JNeurosci, Woon Ju Park, from Georgia Institute of Technology, and colleagues, broached this question by comparing tone detection and pitch discrimination in people with and without sight.

12 Oct 2026

Study identifies Piezo channels as targets for orthodontic care

A new review in Genes & Diseases highlights Piezo channels as important biological links between mechanical forces and the cellular processes that shape the face, move teeth and influence oral health.

12 Oct 2026

Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

Scientists are highlighting long non-coding RNAs (lncRNAs) as promising targets in the effort to overcome one of cancer treatment's most persistent challenges: therapeutic resistance.

12 Oct 2026

RNA modification enzyme FTO shows therapeutic promise in gastrointestinal cancers

A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially important biomarker and therapeutic target across gastrointestinal cancers.

12 Oct 2026

Review highlights EP4 receptor as target for inflammatory diseases

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases.

12 Oct 2026

Targeting mitochondrial vulnerabilities could help treat triple-negative breast cancer

A deeper understanding of mitochondrial function could create new opportunities for treating triple-negative breast cancer (TNBC), one of the most aggressive and difficult-to-treat forms of breast cancer.

12 Oct 2026

Targeting lipophagy could help treat metabolic and oxidative stress-related diseases

A review published in Genes & Diseases highlights lipophagy, the cellular process that selectively breaks down lipid droplets, as a potentially important therapeutic target for conditions driven by disrupted lipid metabolism and oxidative stress.

12 Oct 2026

New review highlights expanding potential of therapeutic DNA vaccines

A new review published in Genes & Diseases highlights the expanding potential of DNA-based vaccines as a flexible platform for preventing infectious diseases, treating cancer and strengthening preparedness for future disease outbreaks.

12 Oct 2026

Vascular anatomy influences experimental stroke treatment effectiveness

A preclinical study from Duke University researchers suggests that the effectiveness of an experimental approach to limiting stroke-related brain injury may depend not only on the drug itself, but also on the brain's collateral circulation: the network of small "backup" blood vessels that can help sustain tissue when a major artery is blocked.

12 Oct 2026

New study tracks how eating behaviors vary with age, sex and body weight

Eating behavior varies with age and body weight. A University of Oulu study found that emotional and uncontrolled eating are more pronounced in younger adults, while cognitive restraint is more common among older people. Sex and body weight also influence which eating behaviors are typical.

12 Oct 2026

Magnetically guided millirobots deliver targeted drugs to beating hearts

Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

12 Oct 2026

Study maps psychological networks linked to suicidal ideation

Suicidal ideation can involve interconnected psychological processes. Researchers from Pusan National University examined 2,018 adults across Italy, Korea, the UK, and the US to map psychosocial networks related to suicidal ideation.

12 Oct 2026