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Engineered regulatory T cells offer a path toward immunosuppression-free transplants

Organ transplantation remains the cornerstone treatment for end-stage organ failure. While conventional broad-spectrum immunosuppression effectively controls acute rejection, it fails to address chronic rejection and carries long-term side effects including infection, malignancy, and metabolic disorders.

8 May 2026

Suppressing TGF-β signaling reactivates dormant bone cells to treat osteoporosis

Osteoporosis, a common skeletal disorder, is marked by reduced bone mass and deterioration of bone microarchitecture, making bones more porous and prone to fractures.

8 May 2026

UK media portrays Type 1 and Type 2 diabetes stigma differently

Media framing often differs between diabetes types, with implications for misconceptions, blame, and diabetes-related stigma.

8 May 2026

AI diagnostic reasoning nears physician performance

Advanced AI systems are approaching physicial-level reasoning in diagnostic tasks.

8 May 2026

Adults of all ages can improve brain performance through practice

A landmark study recently published in the Nature Portfolio journal Scientific Reports reveals that cognitive decline is not an inevitable part of aging.

8 May 2026

New nanoparticles disable drug resistance to achieve complete tumor elimination

Cancer cells frequently develop the ability to expel anticancer drugs before they can work -- a phenomenon called multidrug resistance (MDR) -- which is one of the leading reasons why chemotherapy fails in patients.

8 May 2026

Metformin targets the gut instead of the liver to lower glucose

For decades, physicians and scientists thought metformin, the leading Type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production.

8 May 2026

UK restaurant chains miss most government sugar and salt targets

A study reveals low adherence to UK nutrition targets in major restaurant chains, raising concerns about dietary risks for cardiovascular disease and diabetes.

8 May 2026

Study links mitochondrial health to effectiveness of anti-aging pathways

Mississippi State University biologist Jean-Francois Gout's contributions to a study highlighting key advances in the complexity of aging now are published in Science Advances, a leading peer-reviewed journal of the American Association for the Advancement of Science.

7 May 2026

Diverse leukemia stem cells may drive AML relapse after therapy

Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute have deciphered a key mechanism that contributes to treatment failure in acute myeloid leukemia (AML).

7 May 2026

Blocking TGF-beta may enhance osteoporosis bone regeneration therapies

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state.

7 May 2026

Study reveals how magnetic stimulation repairs depression-related brain circuits

Transcranial magnetic stimulation (TMS) is a non-invasive, FDA-approved therapy that uses brief magnetic pulses to treat depression, particularly in patients who do not respond to medication.

7 May 2026

Scientists identify powerful human antibodies capable of neutralizing measles virus

Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of neutralizing measles virus.

7 May 2026

Garlic-derived compound may help improve muscle strength during aging

Can a compound derived from a common kitchen ingredient help support muscle health during aging? A new study suggests it can.

7 May 2026

Cell swelling in macrophages may trigger stronger inflammatory immune responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system.

7 May 2026

Methylmercury may harm metabolism beyond its known neurological effects

Methylmercury can accumulate in water environments and enter the food chain. Human exposure is of particular concern in communities affected by contaminated rivers, industrial pollution, artisanal gold mining and environmental disasters.

7 May 2026

Aging may reduce anger and frustration linked to past regrets

Older adults report fewer recent regrets than younger adults, finds research published by the American Psychological Association.

7 May 2026

Blood test may improve early tuberculosis detection among household contacts

Household contacts of people with tuberculosis (TB) have a high risk of getting TB themselves, at around 2 percent. It is currently difficult to detect TB in its early stages, or predict who will go on to have TB, and therefore preventive treatment is not widely used.

7 May 2026

Birth weight predicts kidney function during endurance exercise

Researchers investigate how birth weight determines kidney function changes following prolonged physical activity in different environmental conditions.

7 May 2026

Reverse ecology approach reveals hidden complexity in gut microbiome

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

7 May 2026