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Brain’s immune cells play key role in maintaining stability of neuronal networks in Alzheimer's disease

Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain – play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease.

15 Jul 2026

AI model predicts effective immunotherapy combinations for liver cancer

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular carcinoma (HCC) would most benefit from combination treatment using immunotherapy and a targeted therapy that blocks the growth signals that the tumor depends on.

15 Jul 2026

New machine learning model improves cholesterol calculation accessibility

The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk.

15 Jul 2026

Ketogenic diet may increase small intestine cancer risk in mice

A high-fat, low-carbohydrate diet, also called a ketogenic diet, can help some people lose weight by forcing their bodies to burn fat for fuel instead of sugar.

15 Jul 2026

Targeted nanoparticles destroy tumor cells by triggering cuproptosis

A promising cancer treatment strategy called cuproptosis, which uses copper-dependent cell death to eliminate tumor cells, faces a major challenge: many approaches require adding external copper, potentially increasing toxicity beyond the tumor.

15 Jul 2026

New photoswitchable drugs restore light perception in blind animals

Blinding diseases caused by the degeneration of photoreceptors, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP), affect 200 million people worldwide and represent the leading causes of visual impairment and blindness.

15 Jul 2026

Study sheds light on the prognostic value of blood test for predicting cognitive impairment risk

A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a cognitively healthy individual will go on to develop cognitive impairment-a key symptom of Alzheimer's disease.

15 Jul 2026

New project documents vanishing heritage diets for future health benefits

The world's 'heritage' diets could hold vital clues to better health. Writing in Nature Medicine, researchers from 12 countries have launched the World Diet Initiative, a global effort to document and study these diets before this knowledge is lost.

15 Jul 2026

GLP-1 receptor activation linked to lower depression and bipolar disorder odds

Genetic analyses linked BMI-related GLP-1 receptor activation to better mental well-being and lower odds of major depressive disorder and bipolar disorder. The findings do not prove that GLP-1 receptor agonist drugs treat psychiatric conditions, and randomized clinical trials are still needed.

15 Jul 2026

Study links gut microbes to stronger cancer immunotherapy responses

A new study from a team including University of Nebraska–Lincoln researchers is the first to show metabolites produced by certain bacteria in the gut can positively impact the body's immune response to cancer.

14 Jul 2026

Cultural engagement linked to slower physiological aging in older adults

Higher levels of cultural engagement are significantly associated with lower physiological aging, suggests an analysis published online in the Journal of Epidemiology and Community Health.

14 Jul 2026

Patient-derived organoids uncover new targets for chronic pancreatitis treatment

Around three million people worldwide struggle with chronic pancreatitis, a condition wherein the pancreas becomes inflamed, scarred, and painful.

14 Jul 2026

Experimental gene therapy reverses fragile X symptoms in mice

A gene therapy designed to replace the missing protein that causes fragile X syndrome restored several disease-relevant traits in a mouse model, according to a new study published in Gene Therapy.

14 Jul 2026

Study maps how macrophages age across different body tissues

Why does the immune system become less effective as we age? A new USC study published in BMC Biology offers fresh insights by examining a key immune cell type across tissues: macrophages.

14 Jul 2026

Pet gecko offers promising model for cancer research breakthroughs

A new study, led by experts at the University of Nottingham, suggests a pet gecko with an unusually high risk of tumors may be a promising model for understanding how cancer develops and spreads.

14 Jul 2026

Insilico and Bora Pharmaceuticals forge strategic AI-driven drug discovery alliance

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced a multi-target strategic alliance with Bora Pharmaceuticals Co., Ltd., a global leader in pharmaceutical manufacturing.

14 Jul 2026

New review highlights astrocytes' role in chronic traumatic encephalopathy

Researchers from Kansas City University School of Medicine have published a scoping review examining the role of astrocytes in chronic traumatic encephalopathy (CTE).

14 Jul 2026

Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome

Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes in metabolic syndrome (MetS).

14 Jul 2026

New imaging method reveals hidden molecular interactions in cells

Cells are crowded, dynamic places where thousands of molecules interact in tight quarters. Until now, scientists lacked a reliable way to see many of these molecular interactions as they happen.

14 Jul 2026

New report highlights top ten brain health breakthroughs for clinicians

"Understanding Breakthroughs in Brain Health: Top 10 Articles of 2025" - the latest "Top 10" report in the Gerontological Society of America's Insights & Implications in Gerontology series - presents a curated collection of the year's most impactful research on cognitive decline, dementia detection, and brain health across the lifespan, with a focus on actionable insights for primary care providers.

14 Jul 2026