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Estrogen decline alters brain cell matrix in older females

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Study explains how environmental acidity destabilizes internal cellular traffic

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

26 May 2026

Study links ceramide levels to prostate cancer drug response differences

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

26 May 2026

Chronic oral inflammation may impair female fertility and egg quality

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.

26 May 2026

How heat-smart cities can protect outdoor recreation in a warming world

This review shows how rising humid heat threatens the health benefits of nature-based recreation in tropical cities. The authors call for heat-smart urban planning, targeted advisories, and inclusive strategies that keep outdoor activity safe, accessible, and beneficial.

26 May 2026

Neural progenitor timing influences formation of distinct brain layers

The outer regions of the brain, the cortex, have specific layers of different cells - neurons - that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains.

26 May 2026

Why Kenya, Ethiopia, Japan, and the US stand out in global distance running

This global analysis of 152,943 endurance runners found that nationality, gender, age, and race distance were significantly associated with running performance from 1999 to 2024. Men were faster across all distances, women were generally older in longer races, and runners from Kenya, Ethiopia, Japan, and the United States showed distinct participation and performance patterns.

26 May 2026

How a tiny H5N1 dose triggers massive virus shedding in cow milk

Experimental infection studies in lactating Holstein cows showed that H5N1 B3.13 can infect the bovine mammary gland at doses as low as 10 TCID50, producing extremely high viral loads in milk. However, the virus did not transmit to sentinel cows through repeated exposure to contaminated milking equipment or through close contact under high-biocontainment conditions, suggesting that real-world dairy-farm spread depends on additional cofactors.

25 May 2026

Targeted nerve stimulation boosts movement-related brain activity in humans

The vagus nerve connects the brain to major organs throughout the body and plays important roles in many bodily functions.

25 May 2026

Novel RNA modification mechanism drives metabolic fatty liver disease progression

Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with a complex pathogenesis. Although epitranscriptomic modifications such as N6-methyladenosine (m6A) have been implicated in NAFLD, the role of N1-methyladenosine (m1A) and its regulators is largely unexplored.

25 May 2026

New peptide triggers domino effect to suppress bladder cancer

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin-plectin-vimentin/ITGβ4 axis (referred to as the "cytoskeletal domino effect").

25 May 2026

Outdoor running combats winter vitamin D deficiency better than supplements

An EHU study says that vitamin D supplements can help to strengthen the immune system, but not to improve athletic performance.

25 May 2026

Senolytic therapy delays early disc degeneration in mouse model

Targeting senescent cells with dasatinib-quercetin preserves disc structure and modulates degeneration-associated pathways in a mouse model.

25 May 2026

Ferroptosis exploits unique cancer metabolic vulnerabilities to bypass traditional apoptotic evasion pathways

A new wave of scientific understanding is placing ferroptosis, a distinct form of iron-dependent cell death, at the forefront of efforts to overcome drug resistance in digestive cancers. These cancers, which include gastric, colorectal, liver, pancreatic, and esophageal malignancies, remain among the most challenging to treat due to their ability to evade standard therapies.

25 May 2026

Small non-coding RNA molecule precisely controls vital gene expression and cellular balance

A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, monitored, and treated. This microRNA, part of a broader class of non-coding RNAs, plays a critical role in regulating gene activity and maintaining cellular homeostasis.

25 May 2026

Metabolic reprogramming helps tumor cells adapt and evade the human immune system

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the development of more effective therapies.

25 May 2026

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

25 May 2026

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progression and therapeutic response

25 May 2026

Researchers link surgical weight loss to reduced female cancer mortality rates

Substantial and sustained weight-loss has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues to why the risk is reduced - and suggest that gender, metabolism and genetics may play a crucial role.

25 May 2026

New AI model detects hidden antibiotic resistance genes beyond standard databases

resLens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

25 May 2026

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Medical Science News

Estrogen decline alters brain cell matrix in older females

Study explains how environmental acidity destabilizes internal cellular traffic

Study links ceramide levels to prostate cancer drug response differences

Chronic oral inflammation may impair female fertility and egg quality

How heat-smart cities can protect outdoor recreation in a warming world

Neural progenitor timing influences formation of distinct brain layers

Why Kenya, Ethiopia, Japan, and the US stand out in global distance running

How a tiny H5N1 dose triggers massive virus shedding in cow milk

Targeted nerve stimulation boosts movement-related brain activity in humans

Novel RNA modification mechanism drives metabolic fatty liver disease progression

New peptide triggers domino effect to suppress bladder cancer

Outdoor running combats winter vitamin D deficiency better than supplements

Senolytic therapy delays early disc degeneration in mouse model

Ferroptosis exploits unique cancer metabolic vulnerabilities to bypass traditional apoptotic evasion pathways

Small non-coding RNA molecule precisely controls vital gene expression and cellular balance

Metabolic reprogramming helps tumor cells adapt and evade the human immune system

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

New review highlights how glutamine metabolism shapes the complex tumor microenvironment

Researchers link surgical weight loss to reduced female cancer mortality rates

New AI model detects hidden antibiotic resistance genes beyond standard databases

Squid™ Full Range Pipette: Reduce pipette changes, bench clutter, and calibration burden

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

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