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Gut microbiome metabolite butyrate relieves chronic jaw joint pain

Temporomandibular joint (TMJ) pain is associated with disrupted gut microbiome metabolites. Researchers reveal that butyrate, administered as tributyrin, alleviates pain by restoring histone acetylation and reversing gene regulatory changes in the brain.

18 May 2026

Blood test detects tumor DNA to guide advanced cancer treatment

A blood test that detects tumor DNA circulating in the bloodstream may help select the most effective treatment options for cancer patients whose tumors have started to spread, according to one of the largest randomized controlled trials of its kind presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026).

18 May 2026

Body weight and genes directly alter gut microbiota composition

Your body weight and genes influence the types of bacteria you have in your gut. In turn, this appears to affect the risk of developing conditions such as coeliac disease and haemorrhoids.

18 May 2026

Chia seeds may boost fetal brain DHA during obesity-linked pregnancy

Chia seed supplementation during pregnancy increased maternal omega-3 long-chain fatty acids, including DHA, in a rat model of high-fat-high-sugar diet-induced obesity. The findings suggest plant-derived ALA from chia seeds may improve maternal, placental, and mid-gestation fetal brain lipid profiles, but human relevance and offspring outcomes still need testing.

17 May 2026

Aged immune cells may drive memory decline by releasing a brain-aging protein

A preclinical mouse study in Immunity suggests that aged circulating CD8+ T cells can disrupt hippocampal function and impair learning and memory. The findings point to granzyme K, a secreted factor linked to age-associated CD8+ T cells, as a potential target for restoring aspects of cognition in aging.

17 May 2026

AI eye scans reveal who may be at higher risk of osteoporosis

RetiAGE, an AI-derived retinal biological age score, was associated with lower bone mineral density and higher fracture risk scores in older Singaporean adults. In the UK Biobank, older retinal biological age also predicted future osteoporosis, suggesting routine retinal imaging could eventually support opportunistic osteoporosis risk screening.

17 May 2026

AI beats primary care doctors in simulated diagnosis study using images and ECGs

Multi-modal AMIE used state-aware reasoning to interpret patient history alongside skin photos, ECGs, and clinical documents during simulated telehealth consultations. In a blinded exploratory OSCE-style study, AMIE outperformed primary care physicians across most diagnostic, communication, empathy, and multimodal reasoning measures, but still requires real-world clinical validation.

17 May 2026

Healthy plant-based foods may improve pregnancy cardiometabolic markers

Higher-quality plant-based diets were associated with more favorable cardiometabolic biomarkers in pregnant U.S. women, especially higher HDL-C and lower TG/HDL-C ratio. Indices that emphasized healthy plant foods, rather than simply penalizing animal foods, showed the strongest links with insulin resistance and lipid markers.

15 May 2026

Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset of patients benefit. Many solid tumors remain "cold," characterized by poor immune cell infiltration and resistance to immune checkpoint blockade (ICB).

15 May 2026

New technology reveals how RNA shapes influence protein production and stability

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Healthy brain maintenance protects cognitive skills from early Alzheimer's effects

A healthy brain may help protect thinking and memory skills from the early effects of Alzheimer's disease, a new study has found.

15 May 2026

Can supplements slow Parkinson’s disease? Review reveals where the evidence stands

Dietary supplements are widely used by people with Parkinson’s disease, but this review finds that none have yet been proven to slow disease progression. Biotics, nicotinamide riboside, and omega-3 fatty acids combined with vitamin E show the most promise, but larger, longer, and better-designed trials are needed.

14 May 2026

The Goldilocks sleep zone: study links too little and too much sleep to biological aging

The Nature study introduces “Sleep Chart,” a framework linking self-reported sleep duration with 23 biological aging clocks derived from MRI, plasma proteomics, and metabolomics. Across UK Biobank participants, the lowest biological age gaps generally appeared between 6.4 and 7.8 hours of sleep, while shorter and longer sleep were associated with higher disease and mortality risk.

14 May 2026

How Andes virus super-spreaders reveal the risk behind the MV Hondius hantavirus cluster

A 2020 NEJM study of the 2018 to 2019 Epuyén outbreak showed that Andes virus spread from one zoonotic introduction into four generations of human infection, causing 34 cases and 11 deaths. The findings are newly relevant after WHO reported an ANDV cluster linked to the MV Hondius cruise ship, where close indoor exposure may have enabled onboard human-to-human transmission.

14 May 2026

Perioperative medicine emerges as a system wide strategy for better surgery outcomes

Perioperative medicine is emerging as a transformative, comprehensive, system-wide approach to patient care before, during, and after surgery – that reduces complication rates and hospital days, provides better health outcomes, and improves health system performance, according to a special article in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

14 May 2026

The complex peptide mixture that makes ant venom a powerful shield

In addition to serving as biochemical weapons for offense and defense, the venoms produced by ants in the subfamily Formicinae also fulfill additional roles. For example, the ants use it to protect their nests from pathogens. It has long been assumed that the primary constituent of these venoms, formic acid, was responsible for these functions.

14 May 2026

Qureight to support Mediar Therapeutics' Phase 2 trial of MTX-474 in diffuse cutaneous Systemic Sclerosis

Qureight, an end-to-end imaging CRO that provides enterprise-grade imaging and precision endpoints for clinical trials with a focus on lung and heart disease, and Mediar Therapeutics (Mediar), a clinical-stage biotechnology company advancing first-in-class therapies designed to halt fibrosis, today announced Qureight's AI-powered 3D quantitative imaging analytics platform and services will be used to support Mediar's Phase 2 EncompaSSc clinical trial.

From Society for Laboratory Automation and Screening (SLAS) 13 May 2026

Base editing approach repairs deadly Dravet syndrome mutation in mice

Gene editing can repair a DNA error in mice that causes Dravet syndrome, a rare, incurable, and potentially deadly form of childhood epilepsy. After the edit, the mice have far fewer seizures and live much longer.

13 May 2026

Wearable wireless polygraph tracks hidden stress signals

Northwestern University engineers have developed a small, wireless polygraph system you can wear.

13 May 2026

Gene panel predicts chemotherapy response in triple-negative breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have characterized cancer cell-specific features in the tumor microenvironment (TME) of early-stage triple-negative breast cancer (TNBC) tissues, identifying specific macrophage subtypes associated with chemotherapy response.

13 May 2026

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Medical Science News

Gut microbiome metabolite butyrate relieves chronic jaw joint pain

Blood test detects tumor DNA to guide advanced cancer treatment

Body weight and genes directly alter gut microbiota composition

Chia seeds may boost fetal brain DHA during obesity-linked pregnancy

Aged immune cells may drive memory decline by releasing a brain-aging protein

AI eye scans reveal who may be at higher risk of osteoporosis

AI beats primary care doctors in simulated diagnosis study using images and ECGs

Healthy plant-based foods may improve pregnancy cardiometabolic markers

Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

New technology reveals how RNA shapes influence protein production and stability

Healthy brain maintenance protects cognitive skills from early Alzheimer's effects

Can supplements slow Parkinson’s disease? Review reveals where the evidence stands

The Goldilocks sleep zone: study links too little and too much sleep to biological aging

How Andes virus super-spreaders reveal the risk behind the MV Hondius hantavirus cluster

Perioperative medicine emerges as a system wide strategy for better surgery outcomes

The complex peptide mixture that makes ant venom a powerful shield

Qureight to support Mediar Therapeutics' Phase 2 trial of MTX-474 in diffuse cutaneous Systemic Sclerosis

Base editing approach repairs deadly Dravet syndrome mutation in mice

Wearable wireless polygraph tracks hidden stress signals

Gene panel predicts chemotherapy response in triple-negative breast cancer

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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