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Microglia found to drive sleep loss in Alzheimer’s

There’s a small fire isolated in your kitchen. If you had the right tool, you might be able to put it out. But before you can, the sprinklers turn on and flood your entire house.

24 Jul 2026

Spontaneous brain state fluctuations influence real-time memory formation

Most everyday moments are quickly forgotten, while others stay with us for a lifetime. How the brain determines which memories are retained and which are lost remains an open question.

24 Jul 2026

Cambridge scientists solve brain puzzle behind popular obesity drugs

Cambridge scientists have solved the mystery of why both stimulating and blocking a particular 'switch' in the brain can help people lose weight – findings which could help boost the effectiveness of obesity drugs.

24 Jul 2026

Researchers discover molecule to fight age-related muscle decline

Skeletal muscle is one of the first tissues to decline with age. This decline can lead to weakness, scarring, fat accumulation inside muscle, and the loss of fast-twitch muscle fibers that are important for quick and powerful movements.

24 Jul 2026

Oral drug candidate blocks transmission of measles-like disease in ferrets

A new oral antiviral drug candidate administered either before or after direct contact or airborne exposure to canine distemper virus, which causes measles-like disease in ferrets, blocks transmission of the virus and reduces clinical symptoms, according to a study published in the journal Nature Microbiology by researchers in the Center for Translational Antiviral Research (CTAR) at Georgia State University.

24 Jul 2026

Siemens Healthineers launches an industry-leading menu for core lab capillary testing on Atellica analyzers with claims for 24 assays

Siemens Healthineers announced today that it has launched capillary testing on the Atellica CH, IM, and CI Analyzers after receiving CE-mark for 24 capillary blood testing claims, an advancement for capillary testing that offers clinical labs greater confidence in test results and higher throughput.

From Siemens Healthineers 24 Jul 2026

AI redesign helps enzymes evolve beyond natural limits

Researchers showed that AI-redesigned botulinum neurotoxin proteases provided more stable starting points for directed evolution, allowing enzymes to access beneficial mutations that were poorly tolerated in wild-type backgrounds. In BoNT/E models, the approach improved activity, evolvability, and specificity, including an ataxin-2-targeting variant with markedly reduced cleavage of the native SNAP25 substrate.

24 Jul 2026

Bio-inspired ear probe may enhance early hearing loss diagnosis

Binghamton University Assistant Professor Jian Zhou, PhD '18, will lead a five-year, $1.84 million project funded by the National Institutes of Health to create a dual-sensing ear canal probe that will more accurately and reliably detect otoacoustic emissions.

23 Jul 2026

Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

23 Jul 2026

Persistent financial hardship accelerates age-related cognitive decline

Persistent financial hardship accelerates age-related cognitive decline, according to a new study led by University College London (UCL) researchers.

23 Jul 2026

Study provides a practical recall-by-genotype strategy for precision psychiatry research

Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease.

23 Jul 2026

Engineered extracellular vesicles dramatically improve cancer detection sensitivity

Anyone afflicted with cancer will often face a long and difficult journey. The early stages of any medical intervention will necessarily include a biopsy, tissue sample collection, such as a liquid biopsy which uses a blood sample.

23 Jul 2026

Computationally designed antibody attacks previously untreatable KRAS cancer mutations

Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them.

23 Jul 2026

Study sheds light on emerging bacterial cause of urinary tract infections

New research from the University of South Alabama is shedding light on an emerging bacterial cause of urinary tract infections (UTIs) that appears to be more common along the Gulf Coast than previously recognized.

23 Jul 2026

Targeting acid ceramidase could improve healthy aging and longevity

Our population is aging. The United Nations reports that by 2050, the number of people over the age of 85 on our planet is set to triple.

23 Jul 2026

Endotrophin may reveal metabolic risks linked to changing body fat

Researchers have identified a biological marker that rises and falls as body fat changes, offering new insight into how weight gain and weight loss may influence metabolic health.

23 Jul 2026

Evidence shows artificial sweeteners cannot be judged as a single group

This narrative review found that non-nutritive artificial sweeteners have compound-specific and context-dependent associations with gut microbiota, metabolism, and health-related outcomes. Evidence does not support treating all sweeteners as uniformly harmful or safe, with human findings often limited or inconsistent.

23 Jul 2026

Study reveals dynamic remodeling of genome architecture during brain aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

23 Jul 2026

MEK inhibition could limit T cell exhaustion and give a boost to immunotherapy

A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors.

23 Jul 2026

Researchers develop artery-on-a-chip platform to predict stroke risk

Predicting an individual's risk of ischemic stroke is difficult because thrombosis embolization-the process of a blood clot detaching from the area where it formed and traveling to and then sticking in another blood vessel-is based on factors that are unique to each person.

23 Jul 2026