Medical Science News

RSS

The Mediterranean diet has a modern problem, and it isn't just about food

A narrative review published in Applied Sciences examined how urbanisation, time constraints, food costs, and changing lifestyles have contributed to declining adherence to the Mediterranean diet. Drawing on 116 references, the authors identified workplace and school interventions, nutrition education, physical activity, and Mediterranean-inspired convenience foods as potential strategies for adapting this dietary pattern to modern life.

5 Nov 2026

Hidden genetic differences in gut bacteria may hold clues to aging

Researchers analyzed approximately 12.8 million gut microbial genetic variants in 10,781 individuals across six cohorts, identifying 940 independent associations with 69 human health characteristics and environmental exposures. Nearly two-thirds of these associations were not accompanied by significant differences in bacterial species abundance, suggesting that microbial genetics can reveal relationships overlooked by conventional microbiome analyses, although causality remains unproven.

5 Nov 2026

Review examines translational bottlenecks for plant-derived anti-inflammatory compounds

A review led by Professor Weidong Zhang at the School of Pharmacy, Naval Medical University, was published in Volume 2 of the journal Immunity & Inflammation on October 27, 2026. The article systematically examines the translational bottlenecks and potential solutions for plant-derived anti-inflammatory compounds.

5 Nov 2026

CIRM grant funds new stem cell therapy to heal hearts

A new $6.9 million grant from the California Institute for Regenerative Medicine (CIRM) will support preclinical development of an investigational cell therapy for the heart created by USC Stem Cell scientists.

5 Nov 2026

Study shows opposite synaptic mechanisms cause identical cognitive deficits

A research team led by Dr. SHENG Nengyin of the Kunming Institute of Zoology (KIZ) of the Chinese Academy of Sciences has reframed ZC4H2-associated rare disorder (ZARD)-a disorder marked by intellectual disability, developmental delays, muscle weakness, and other neurological or physical abnormalities-as a "disease spectrum" rather than a condition driven by a single mechanism.

5 Nov 2026

AI-designed vaccine provides complete protection against diverse bird flu variants

A University of Cambridge team has had a third success with their AI-guided technique for designing vaccines against highly infectious viruses that threaten animal and human health.

5 Nov 2026

Vulnerable DNA sites make cancer cells sensitive to PARP inhibitors

A small subset of vulnerable DNA sites can make cancer cells highly sensitive to targeted drugs called PARP inhibitors, a new study shows.

5 Nov 2026

Compound YZG-331 leverages gut microbiota to improve sleep in mouse models of insomnia

This new article publication from Acta Pharmaceutica Sinica B discusses how interactions between the investigational compound YZG-331 and the gut microbiota contribute to its sleep-promoting effects in mouse models of insomnia.

5 Nov 2026

Anti-PEG antibodies drive contrasting liposome skin toxicity across species

This new article publication from Acta Pharmaceutica Sinica B discusses how anti-polyethylene glycol antibodies affect the movement of stealth liposomes from blood into skin, revealing contrasting distribution and toxicity patterns in mice and rats.

5 Nov 2026

Pattern-based patient selection associated with positive clinical trial results

This new article publication from Acta Pharmaceutica Sinica B discusses the association between using traditional Chinese medicine patterns to select participants and statistically significant primary outcomes in randomized placebo-controlled trials of Chinese herbal formulas.

5 Nov 2026

New covalent inhibitor targets DNAJC9 to reduce sepsis inflammation

This new article publication from Acta Pharmaceutica Sinica B discusses the discovery of the covalent inhibitor A12 and the identification of DNAJC9 as a potential drug target for sepsis-associated inflammation.

5 Nov 2026

Innovative framework advances EEG-based emotion recognition

Emotion recognition plays an important role in understanding human cognition and behavior, and has potential applications in brain-computer interfaces and mental health monitoring.

5 Nov 2026

Topadur’s Phase 2a trial of TOP-N53 for systemic sclerosis-associated digital ulcers advances to next dose levels

Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced that the Safety Review Committee of its Phase 2a trial has recommended progression to the next planned dose levels.

5 Nov 2026

Elusive HIV strains cause breakthrough infections after antibody treatment ends

The broadly neutralizing antibody VRC01 has been thoroughly vetted as a potential prophylactic that could prevent people from becoming infected with HIV.

5 Nov 2026

Scientists develop slug-inspired hydrogel to seal gastrointestinal fistulas

Gastrointestinal fistulas are abnormal passages between the digestive tract and another organ or tissue. They are a common complication of surgery, trauma, inflammatory diseases, and malignant tumors and can be life-threatening in severe cases.

5 Nov 2026

Engineered IL-39 cytokine unlocks new pathways for immunotherapy

In a new preclinical study, scientists present a molecular engineering approach to modify and repurpose a cytokine named IL-39, which plays a central role in inflammation and immunity.

5 Nov 2026

Graded physical activity prescriptions improve functional outcomes in psychiatry

Most of us have heard the advice so often that it has worn smooth, like a stone in a river: get some exercise. A new peer-reviewed Viewpoint in Brain Health, drawing on randomized trials, meta-analyses, and cohort studies, argues that this familiar sentence has been doing the wrong job.

5 Nov 2026

Organoid coculture platforms enhance preclinical prediction of drug efficacy

Three‐dimensional cancer organoids cultured in vitro closely recapitulate the phenotypic and genetic features of parental tumor tissues, making them powerful tools for cancer research, drug screening, and personalized medicine.

5 Nov 2026

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

Longer reproductive lifespan and hormonal history may influence brain vascular health

A longer reproductive lifespan and a history of using birth control pills or menopausal hormone therapy were associated with certain signs of blood vessel health in the brain, according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026