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Protein MIIP suppresses colorectal cancer by regulating immune cell signaling

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited responses to immunotherapy in most patients.

16 Mar 2026

Researchers develop targeted delivery system for poorly soluble cancer drugs

Recent advances in drug discovery research have led to the development of numerous drug candidate compounds with high therapeutic efficacy.

16 Mar 2026

Clinicians show modest response to elevated lipoprotein levels in low-risk patients

Elevated Lipoprotein(a) [Lp(a)] is an independent, genetically determined risk factor for atherosclerotic cardiovascular disease (ASCVD), with levels >50 mg/dL affecting 20–30% of the global population.

16 Mar 2026

Gold nanoclusters may help detect diseases from blood samples

An extensive computational study by researchers from the University of Jyväskylä (Finland) predicted that gold nanoclusters could selectively recognize chiral biomolecules.

16 Mar 2026

Brain waste clearance dysfunction may predict the onset of psychosis

How can we explain the onset of psychotic symptoms characteristic of schizophrenia? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their emergence remain poorly understood.

16 Mar 2026

Can Ashwagandha gummies help kids focus better?

A study shows Ashwagandha gummies may enhance cognitive performance and sleep quality in children, offering a safe herbal approach to support development.

16 Mar 2026

Why do some people respond better to GLP-1 drugs? Gut microbiome may hold clues

A review in the Canadian Journal of Physiology and Pharmacology examines emerging evidence linking glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the gut microbiome, and obesity treatment outcomes. The authors conclude that microbiome changes seen during therapy are most likely driven by diet, behavior, and weight loss, although microbial profiling may eventually help predict patient responses.

15 Mar 2026

Vaginal microbiome may play key role in pregnancy health and preterm birth risk, researchers say

Researchers reviewed evidence linking the vaginal microbiome to pregnancy health and spontaneous preterm birth, highlighting how Lactobacillus-dominated communities help maintain immune balance and vaginal acidity. Dysbiosis and inflammatory signaling may contribute to preterm birth risk, while emerging microbiome-targeted therapies aim to restore protective microbial ecosystems.

15 Mar 2026

Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

Researchers found that very small numbers of gut bacteria can translocate to the brain in mice, particularly when gut barrier permeability increases due to a Paigen diet. Evidence suggests the vagus nerve may serve as a partial route for this gut-to-brain microbial movement.

15 Mar 2026

Vitamin B2 metabolism helps cancer cells resist ferroptosis

A lack of vitamin B2 makes tumour cells more susceptible to a unique form of cell death. This was discovered by researchers at the Rudolf Virchow Centre at the University of Würzburg.

13 Mar 2026

FDA-approved drug fedratinib enhances communication between cellular organelles

Cells behave like cities and organelles carry out infrastructural roles: Mitochondria are powerhouses, the endoplasmic reticulum serves as a transport hub and lysosomes help with waste disposal.

13 Mar 2026

Early prenatal shunt treatment improves outcomes for fetal megacystis

An interdisciplinary team from the University Hospitals Cologne and Bonn have conducted the first prospective study to investigate whether very early intervention in unborn children with congenital lower urinary tract obstruction (cLUTO) can improve their chances of survival and subsequent kidney function.

13 Mar 2026

Updated EULAR recommendations guide treatment decisions for rheumatoid arthritis

First published in 2010, the EULAR recommendations for the management of RA, the most frequent inflammatory rheumatic disease, have been relied upon by healthcare professionals and organisations worldwide to offer an up-to-date and robust analysis of the effectiveness and practical use of available DMARDs – from conventional agents such as methotrexate to biologics and Janus kinase (JAK) inhibitors.

13 Mar 2026

New statement released on the use and interpretation of spirometry for COPD diagnosis

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the Global Lung Function Initiative (GLI) have published a joint statement on the use and interpretation of spirometry for the diagnosis of COPD.

13 Mar 2026

New insights highlight multifaceted roles of CD4+ T cells in tumor immunity

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell killing.

13 Mar 2026

Circular RNA produced by HIV boosts viral replication

For decades scientists have recognized that human immunodeficiency virus (HIV) is a formidable viral pathogen.

13 Mar 2026

Targeting two influenza proteins may reduce viral transmission

A long-running debate in vaccine design revolves around whether a vaccine should be optimized to prevent the virus from replicating inside an infected host or prevent the virus from transmitting to others.

13 Mar 2026

SonoPIN technology boosts intracellular delivery of large cancer drugs

Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer drugs enter tumor cells and cause them to self-destruct.

13 Mar 2026

New RNA therapy enhances the heart's ability to repair itself after injury

After a heart attack, cardiologists can reopen blocked vessels and restore blood flow, but the muscle cells that died will never be replaced.

13 Mar 2026

New method creates longer lasting CAR T cells for cancer therapy

A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments.

13 Mar 2026