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Why some people can’t lose weight even when they follow the rules

New research reveals biological factors, not just effort, influence weight loss success, highlighting the need for personalized diet and exercise interventions.

13 Jan 2026

Dietary protein reshapes how cholera bacteria colonize the gut

Researchers investigate the role of dietary components and the gut microbiota in cholera.

13 Jan 2026

Discovery lays foundation for understanding how the cell senses membrane injuries

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell.

12 Jan 2026

Study shows biosynthetic method to make low-calorie sugar substitute

From saccharin in the 19th century to stevia and monk fruit in the 21st, researchers and the food industry have long sought a sweetener that delivers the taste of sugar without its drawbacks-excess calories, tooth decay, and heightened risk for obesity, insulin resistance, and diabetes.

12 Jan 2026

New publication describes the chemical journey of non-hormonal male birth control pill

A newly published manuscript authored by Dr. Gunda Georg, YourChoice Therapeutics and Columbia University Medical Center describes the chemical journey of YCT-529, a non-hormonal male birth control pill, and the promising molecular science behind it.

12 Jan 2026

Brain immune cells drive persistent negative emotions after repeated binge drinking

New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying driver of prolonged negative feelings caused by repeated, sustained binge drinking (binge exposure).

12 Jan 2026

Gene regulators could restore the aging body's ability to self-repair

As we age, we don't recover from injury or illness like we did when we were young. But new research from UCSF has found gene regulators - proteins that turn genes on and off - that could restore the aging body's ability to self-repair.

12 Jan 2026

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for triple‑negative breast cancer (TNBC), the most aggressive subtype of breast cancer.

12 Jan 2026

Two harmful gene variants can combine to restore normal protein function

In a groundbreaking study published in the in Proceedings of the National Academy of Sciences (PNAS), scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease.

12 Jan 2026

Gut bacteria protect mice from deadly secondary pneumonia after influenza

Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

12 Jan 2026

Rare sugars activate metabolic signaling to reduce alcohol consumption in mice

While investigating the FGF21-oxytocin-dopamine system, a mechanism that regulates sugar appetite, a team of researchers at Kyoto University noticed reports suggesting that the protein FGF21 may regulate alcohol ingestion.

12 Jan 2026

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics.

12 Jan 2026

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

Sinai Health researchers have shown a blood test that can predict Crohn's disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention.

12 Jan 2026

New insights into how rhythmic brain waves create a coherent sense of bodily self

A new study from Karolinska Institutet, published in Nature Communications, reveals how rhythmic brain waves known as alpha oscillations help us distinguish between our own body and the external world.

12 Jan 2026

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Smoking tobacco is known to worsen symptoms of periodontitis and reduce responsiveness to treatment. Using high-resolution spatial transcriptomics, researchers identified differences between smokers and non-smokers in the expression of genes that weaken gum epithelial integrity and cause bone damage through inflammation.

12 Jan 2026

Researchers discover how aggressive breast cancer controls protein production

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its production of proteins has been discovered by researchers at Umeå University, Sweden.

12 Jan 2026

Why adherence determines weight loss success with semaglutide

Researchers examine how the effectiveness of weight-loss medications may depend on the patient adherence.

12 Jan 2026

Long COVID symptom clusters that could reshape patient care

A systematic review of Long COVID identifies symptom clusters, highlighting fatigue and proposing a management framework for personalized treatment strategies.

12 Jan 2026

Weight loss normalizes fat tissue at cellular level

It is well known that obesity typically leads to inflammation and dysfunction of fat tissue that increases the risk of developing metabolic diseases such as diabetes and cardiovascular diseases.

12 Jan 2026

Whole-genome sequencing improves PARP inhibitor treatment prediction

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

12 Jan 2026

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Medical Science News

Why some people can’t lose weight even when they follow the rules

Dietary protein reshapes how cholera bacteria colonize the gut

Discovery lays foundation for understanding how the cell senses membrane injuries

Study shows biosynthetic method to make low-calorie sugar substitute

New publication describes the chemical journey of non-hormonal male birth control pill

Brain immune cells drive persistent negative emotions after repeated binge drinking

Gene regulators could restore the aging body's ability to self-repair

Study identifies PUF60 as a critical vulnerability in triple negative breast cancer

Two harmful gene variants can combine to restore normal protein function

Gut bacteria protect mice from deadly secondary pneumonia after influenza

Rare sugars activate metabolic signaling to reduce alcohol consumption in mice

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

New insights into how rhythmic brain waves create a coherent sense of bodily self

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Researchers discover how aggressive breast cancer controls protein production

Why adherence determines weight loss success with semaglutide

Long COVID symptom clusters that could reshape patient care

Weight loss normalizes fat tissue at cellular level

Whole-genome sequencing improves PARP inhibitor treatment prediction

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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