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Researchers uncover molecular pathway controlling bone resorption and tooth eruption

RUNX2 is best known as a master transcription factor of osteoblast differentiation. Mutations in, or haploinsufficiency of RUNX2 cause CCD, a skeletal disorder characterized by delayed permanent tooth eruption, supernumerary teeth and clavicular defects.

30 Oct 2026

Excessive exercise disrupts dopamine regulation in the brain, study finds

Excessive physical exercise affects more than just the muscles; it can also alter brain chemistry. A new study published in the journal Neuroscience revealed that exhaustive training without adequate rest alters the regulation of dopamine in the hippocampus, a brain region closely linked to memory and the regulation of emotions.

30 Oct 2026

Light-activated molecular cages offer precise control over protein degradation

Researchers have created a molecular "cage" that keeps protein-degrading drug molecules inactive until they are exposed to low-energy red light.

30 Oct 2026

Space-grown organoids better replicate aggressive glioblastoma tumors

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and is one of the most aggressive and deadly forms of cancer.

30 Oct 2026

Immunotherapy reshapes immune cell interactions in melanoma-affected lymph nodes

A new study from Mayo Clinic suggests checkpoint immunotherapy may reshape the immune environment within lymph nodes after melanoma has spread to them.

30 Oct 2026

Myeloid immune cells play key roles in aortic health and disease

The aorta is often viewed primarily as the body's largest blood vessel-a durable conduit that delivers oxygen-rich blood from the heart to every organ.

30 Oct 2026

TIBI researcher receives NIH grant for 3D-bioprinted retinal grafts

We are pleased to announce that Dr. Johnson V. John, Assistant Professor at the Terasaki Institute for Biomedical Innovation (TIBI), has received an R56 grant from the National Eye Institute (NEI) of the National Institutes of Health (NIH).

30 Oct 2026

Cold showers improve personal health while reducing carbon emissions

How can we encourage people to adopt more environmentally friendly habits? To explore this question, a psychologist at the University of Basel asked participants in a study to take cold showers. Those who stuck with the routine experienced several benefits.

30 Oct 2026

Hyperactive cancer-promoting proteins help tumor cells evade immune attack

The immune system may recognize a cancer cell and still fail to destroy it. Researchers at Hiroshima University and their international collaborators found that hyperactive YAP and TAZ (YAP/TAZ), two cancer-promoting proteins, were associated with genomic instability that may make cancer cells more recognizable to the immune system, while also increasing PD-L2, which helps the cells suppress T-cell attack.

30 Oct 2026

Study finds unexpected lower gut bacterial diversity in vegans

The gut is home to billions of microorganisms. It is a complex ecosystem that regulates many of the body's functions and helps keep us healthy – when it is in balance.

30 Oct 2026

Ankle bones change throughout life depending on footwear choices

We tend to think of our bones as solid, unchanging support structures inside our bodies, but a recent study from the University of Chicago shows just how much bones can change depending on how we use them.

30 Oct 2026

Mayo Clinic enters new medical era with precure research

Mayo Clinic researchers are uncovering the earliest shifts in disease biology - long before symptoms appear - revealing how disease takes root and opening new possibilities to identify, predict and potentially prevent disease before symptoms develop.

30 Oct 2026

Targeting specific enzyme reverses radiation-induced immune suppression in cancer

Researchers at the University of Chicago identified a mechanism to make immune cells reprogrammed by radiation therapy attack tumors rather than protect them.

30 Oct 2026

Targeting ANO6 protein weakens pancreatic cancer and boosts immunity

Fox Chase Cancer Center researchers identified a potential therapeutic target for pancreatic cancer after showing that tumor growth can be slowed and immune suppression can be reduced in preclinical trials by blocking a particular protein, called anoctamin 6 (ANO6).

30 Oct 2026

Testosterone shows no evidence of improving menopausal brain fog

Published in Reproduction and Fertility, the review examined five existing studies of women aged 41 to 65 to understand whether testosterone treatment improves thinking and memory in women during and after menopause.

30 Oct 2026

Platelet hyperactivity drives glioblastoma progression and deep vein thrombosis

New Cleveland Clinic research published in Cancer Cell shows that people with glioblastoma have more active platelets, which are cells involved in blood clotting. Platelets also communicate with other cells and can influence immune activity. The overactive platelets in people with glioblastoma slow the activity of cancer-fighting T cells, which can contribute to tumor growth and cancer progression.

30 Oct 2026

Study reveals immune rheostat maintaining skin barrier homeostasis

As the steadfast protector of the body's interior, the skin must be able to swiftly respond to stressors from the outside world and then return to a steady state in order to maintain everyday operations. Coordinating that agile response are epidermal stem cells, which produce the overlying protective layers of specialized skin cells sent to the surface while also maintaining a ready pool of new stem cells to draw from.

30 Oct 2026

Curiox Biosystems strengthens commercial leadership to expand adoption of centrifuge-free sample preparation

Curiox Biosystems Inc (Curiox), a provider of centrifuge-free (C-FREE™) sample preparation technologies for reproducible, automated flow cytometry workflows, today announced the expansion of its senior commercial team and the formation of a Strategic Advisory Board (SAB).

From Curiox Biosystems 30 Oct 2026

Discarded fruit and vegetable parts offer overlooked fiber benefits

Most of us routinely discard the peels, skins, stalks, and seeds of fruits and vegetables at mealtime. But new research from King's College London suggests these scraps could be a valuable – and overlooked – source of dietary fiber, offering potential benefits for both public health and the environment.

29 Oct 2026

Major studies identify accurate non-invasive tests for liver disease

Two major international studies have delivered the strongest evidence to date on which non-invasive tests can accurately diagnose and measure the severity of metabolic dysfunction-associated steatotic liver disease (MASLD) and its more severe form, MASH, reducing reliance on liver biopsy.

29 Oct 2026