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Review outlines key strategies to overcome antibody drug conjugate resistance

The first Antibody-drug conjugate (ADC) was approved overa quarter-century ago, and today more than 20 have reached the clinic.

24 Jun 2026

Duke researchers discover molecules that target vital cell signaling proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

24 Jun 2026

Study outlines legal challenges for fetal tissue research in Japan

Human fetal tissue research has contributed to advances in developmental biology, the study of congenital diseases, regenerative medicine, and vaccine development.

24 Jun 2026

Using blood proteomics to identify pediatric inflammatory bowel disease risk

For children with suspected inflammatory bowel disease (IBD), a chronic, relapsing condition of the gastrointestinal tract, getting the right diagnosis relies on a combination of clinical evaluation, imaging, endoscopy, and histopathology.

24 Jun 2026

Natural microbial compound helps protect the gut from chronic inflammation

University of Louisville researchers have discovered how a naturally occurring microbial compound may help protect the gut and support future treatment strategies for inflammatory bowel disease (IBD).

24 Jun 2026

New eye imaging technology captures clearer details of retina

Modern OCT devices can look inside the eye without a scalpel - but they do not always capture everything that matters. Some critical information is simply lost, blurred by scattered photons.

24 Jun 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026

LMU researchers discover new genetic cause of Crohn's disease

A team led by LMU physician Daniel Kotlarz has identified a previously unknown genetic cause of Crohn's disease.

24 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

Zebrafish model unlocks new insights into hereditary brain disease

CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brain’s small blood vessels, leading to strokes, cognitive decline, and early dementia.

24 Jun 2026

Common genetic difference may increase the risk of severe COVID-19 and lung fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

24 Jun 2026

Study reveals early immune clues to predict active tuberculosis risk

An early view of the immune response to bacteria in the lungs provides clues as to why some people keep TB in check, while others develop disease, suggesting new ways to intervene earlier and stop TB.

24 Jun 2026

New pathway speeds up biliary atresia diagnosis in newborns

BA is difficult to detect because early jaundice can resemble common newborn conditions, and pale stools may not appear immediately.

24 Jun 2026

Electroacupuncture relieves neuropathic pain and anxiety by activating specific brain circuit

Neuropathic pain affects nearly 10% of the global population, and up to 60% of those individuals also struggle with anxiety or other mood disorders.

24 Jun 2026

FairJourney Bio and AbTherx partner to offer fully integrated antibody discovery

FairJourney Bio (“FJBio”), a global antibody discovery expert, has entered a partnership with AbTherx, Inc. to bring transgenic mouse-based antibody discovery in-house. The agreement gives the Company access to AbTherx’s Atlas™ Full Human Diversity (FHD) and Common Light Chain (cLC) mouse technologies, completing a discovery route that partners can now run end to end entirely within FJBio’s integrated workflow.

From FairJourney Biologics S.A. 24 Jun 2026

Human-AI teams improve healthcare only when clinicians stay in control

A scoping review of 140 empirical studies found that human-AI collaboration in healthcare reports the most consistent benefits in diagnostic interpretation, especially when AI supports bounded tasks and clinicians retain final responsibility. Evidence remains fragmented across triage, treatment planning, and documentation, with few studies measuring patient outcomes, system impact, trust calibration, or governance in real-world settings.

24 Jun 2026

Melatonin improves skin flap survival by reducing ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

23 Jun 2026

New microneedle patch offers enzyme-free continuous glucose monitoring

More than 500 million people worldwide live with diabetes, making reliable continuous glucose monitoring (CGM) a critical yet unmet need.

23 Jun 2026

Micro and nanorobots could transform blood clot treatment

Newer tethered devices address some of these limitations: the "milli‑spinner" thrombectomy device applies compressive and shear loading to compact a clot to about 10% of its original volume, enabling ultrafast removal even in pulmonary and cerebral arteries (in vitro and porcine studies).

23 Jun 2026

Circadian rhythm influences calorie burning after eating

Han-Chow Koh, PhD, and Frank A.J.L. Scheer, PhD, of the Medical Chronobiology Program at the Division of Sleep and Circadian Medicine in the Mass General Brigham Department of Medicine, are the co-lead and senior author, respectively, of a paper published in Metabolism, "Constant-routine protocol reveals an endogenous circadian rhythm in diet-induced thermogenesis with a peak in the biological morning."

23 Jun 2026