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Scientists discover BRCA links to head and neck cancer risks

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered associations between pathogenic variants of the BRCA 1 and 2 genes and four types of cancer. Published in ESMO Open, the findings expand the potential for personalized medicine to several cancer types that currently have limited treatment options and poor prognoses.

17 Apr 2026

Researchers use tiny glass capillaries to sample living cancer cell parts

A new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first

17 Apr 2026

Scientists link poor sleep to decreased chemotherapy response via the gut

Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.

17 Apr 2026

Psychedelic use is associated with major life changes across 10 domains

Researchers created a new questionnaire to measure major life changes linked to psychedelic use and found that most surveyed adults reporting naturalistic psychedelic use said psychedelics had influenced at least one major change in their lives. These changes most often involved goals, values, and spirituality, were usually rated positively, and were more commonly reported by people with more frequent use.

16 Apr 2026

Why AI is becoming a powerful tool in cancer drug discovery

This Perspective reviews how AI is moving drug discovery from long, costly experimental pipelines toward earlier clinical translation, with an AI-designed TNIK inhibitor trial serving as an important proof-of-feasibility reference point. It argues that precision oncology could benefit from AI-driven integration of multi-omics, federated learning, and adaptive trial design, but only if validation, fairness, interpretability, and regulatory alignment improve.

16 Apr 2026

Study finds popular AI chatbots often give problematic health advice

Researchers audited five popular public-facing AI chatbots across 250 health prompts and found that 49.6% of responses were problematic, with especially weak performance on open-ended questions and in nutrition and athletic performance. The study also found poor citation quality, difficult readability, and very few refusals to answer, raising concerns about the reliability of chatbots for everyday health information.

16 Apr 2026

How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

This review argues that neurodegeneration is shaped not only by toxic protein buildup but also by immune signaling, with microglia and T cells able to either protect the brain or worsen damage depending on context. It also highlights aging, head injury, and viral infection as major forces that reshape CNS immunity and may influence disease progression and future treatment strategies.

16 Apr 2026

Clinical barriers prevent hormone therapy access after cervical cancer treatment

Most oncologists say they would prescribe hormone therapy to cervical cancer patients who experience early menopause from radiation treatment, but barriers are keeping many from doing so in practice, according to a new University of Kentucky Markey Cancer Center study published in JAMA Network Open.

16 Apr 2026

Study reveals why endometriosis pain persists after lesions are removed

Repeated menstrual cycles may do more than trigger endometriosis. They may rewire the brain.

16 Apr 2026

Understanding cell messaging provides a blueprint for targeting inaccessible tumors

Researchers at University College Dublin have discovered a previously unknown "courier system" that cells use to deliver coherent biological messages between each other, opening new possibilities for medicine and biotechnology.

16 Apr 2026

New research reveals how bacteria "selflessly" share DNA through GTAs

Research has shed important new light on the enemies-turned-allies that allow bacteria to exchange genes, including those linked to antimicrobial resistance (AMR).

16 Apr 2026

Superficial skin exposures pose a higher rabies risk than previously thought

While it was previously thought that keratinocytes (skin cells) were only passive conductors that allow the rabies virus to pass through, novel research reveals that these cells play a much more active role. The findings of a new study in the Journal of Investigative Dermatology (JID), published by Elsevier, provide direct evidence that keratinocytes can support viral replication and transmit the rabies virus to neurons. The investigators offer a mechanistic explanation for how superficial skin exposures from scratches or minor bites by dogs and bats can lead to neuroinvasion, contributing to the risk of infection.

16 Apr 2026

Epigenetic changes allow cancer cells to shift identity and survive drugs

Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute for Systems Biology (ISB) shows that cancer cells may begin escaping therapy much earlier - as the therapy itself triggers a stress response that drives some cancer cells into a temporary drug-tolerant state.

16 Apr 2026

Researchers discover how stress signals weaken the aging immune system

As we age, our ability to maintain healthy blood and a strong immune system gradually declines, largely because hematopoietic stem cells (HSCs), the cells responsible for producing all blood cell types, begin to lose their effectiveness. Normally, HSCs can both self-renew and generate a balanced mix of blood cells, but over time they produce fewer new cells, favor certain cells such as myeloid cells over lymphoid cells, and struggle to support a robust immune response.

16 Apr 2026

Can processed meats fit into a healthy diet?

This perspective-style review argues that processed meats remain valuable sources of high-quality protein, essential amino acids, and bioavailable micronutrients despite concerns about sodium, fat, and chronic disease links. It also contends that much of the evidence tying processed meat to adverse health outcomes is observational and potentially confounded, while emphasizing the role of processing in safety, shelf life, and food security.

15 Apr 2026

Are healthy foods really healthy? Nutrition researchers say context matters

This Clinical Nutrition opinion paper argues that nutrition research should stop asking whether a food is simply “healthy” and instead ask what it is being compared with. Because diets are compositional, the health effects of foods depend on the specific substitution, and the authors argue that causal inference and network meta-analysis can improve how evidence is interpreted.

15 Apr 2026

Lower-protein toddler formula does not reduce BMI at age 2, trial finds

A large randomized trial in Germany and Spain found that lowering milk protein intake during the second year of life did not reduce BMI z-score at 24 months, though it did produce a temporary BMI reduction at 18 months. Lower protein intake also led to more stable weight and length trajectories, while higher protein intake pushed growth upward relative to WHO standards.

15 Apr 2026

New flu vaccine approach targets multiple virus strains

Doctors recommend getting your flu shot annually, since the specific influenza strain it targets varies from year to year. But what if the shot could be more effective while protecting against more strains?

15 Apr 2026

Study explains failure of cellular cleanup in neurodegenerative diseases

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled.

15 Apr 2026

Mitochondrial activity keeps dendritic cells ready to fight disease

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular metabolism to gene regulation and T-cell activation.

15 Apr 2026