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Gut bacterial molecule discovered to drive serious bile duct disease

Researchers at the University of Oslo and Oslo University Hospital have, together with international collaborators, discovered that a small molecule made exclusively by gut bacteria can actively drive disease in the bile ducts and worsen primary sclerosing cholangitis (PSC), a serious liver and bile duct disease.

4 Sep 2026

Lab-grown micro bladder helps explain why urinary tract infections return

A lab-grown micro bladder may explain why urinary tract infections (UTIs) return so frequently, according to a study led by researchers at UCL, the University of Oxford and the University of Leicester.

4 Sep 2026

Tumor environments sculpt diverse natural killer cells for cancer therapies

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

4 Sep 2026

Most oncology AI research overlooks critical patient safety and privacy

Flinders University researchers were part of an international team that conducted a scoping review that identified 2,441 records and found just 32 studies examined how cancer patients, survivors and carers feel towards generative AI being used in their care.

4 Sep 2026

Crucial brain stem cells rely on metabolic pathways to make decisions

As the human brain takes shape before birth, a remarkable type of stem cell helps give it many of the features that make it distinctly human.

4 Sep 2026

Extreme long-distance running triggers major surge in body's cannabis-like molecules

A marathon, 100 kilometers or even 230 kilometers in one go: Anyone running such distances puts enormous strain on their body.

4 Sep 2026

Research reveals how natural enzymes transcribe expanded eight-letter genetic code

All known life on earth utilizes the same genetic alphabet, consisting of four letters. Now, researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet.

4 Sep 2026

Submicron IR map of the human cell: Label free cellular imaging with O-PTIR, FTIR and Raman

What if you could map the chemistry inside a human cell - without fluorescent labels or stains?

From Photothermal Spectroscopy Corp 4 Sep 2026

What your gut microbes may have to do with how your brain ages

This review examines how diet-driven changes in the gut microbiota and microbial metabolites may influence cognitive aging through immune, metabolic, neural, endocrine, and barrier-related pathways. It highlights SCFAs, tryptophan-derived metabolites, and bile acids as key signaling mediators while emphasizing that much of the mechanistic evidence remains preclinical and human evidence is largely associative.

3 Sep 2026

What 107 professional MMA fighters actually ate before and after weigh-in

Professional UFC fighters followed highly structured dietary patterns around competition, sharply restricting carbohydrates, fiber, fluids, and sodium before weigh-in before rapidly increasing carbohydrate, fluid, and sodium intake afterward. Despite aggressive post-weigh-in refueling, carbohydrate intake fell again on fight day, suggesting that some fighters may not fully restore glycogen stores before competition.

3 Sep 2026

What your genes can, and cannot, tell us about your personality

A meta-analysis of 46 cohorts involving 611,037 to 1.14 million participants identified 1,260 lead genetic variants associated with the Big Five personality traits, including 824 in previously unlinked genomic regions. The associations were broadly consistent across cohorts and measurement contexts, while polygenic analyses linked personality-related genetics to health, behavior, psychopathology, and life outcomes, although effects were modest and could not predict individual behavior.

3 Sep 2026

Semaglutide extended lifespan in older female mice, but that was not the only finding

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced calorie intake alone.

3 Sep 2026

The four-day week has plenty of fans. Now researchers are testing what it really changes

The Sussex 4-Day Week study is a 14-week UK protocol designed to investigate how reduced working hours affect physical and mental health, wellbeing, sleep, work performance, and potential biological and psychological mechanisms. Researchers aim to combine questionnaires with actigraphy, inflammatory biomarkers, interoception testing, and brain imaging in at least 150 adults, with data collection expected to continue until 2027.

3 Sep 2026

Study finds biases in tools predicting dangerous genetic mutations

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

3 Sep 2026

Cancer-fighting T cells need small amounts of ROS to attack tumors, study finds

New research reveals a promising new target for treating cancer by harnessing a type of molecule previously thought to do more harm than good.

3 Sep 2026

Eight-year study reveals how molecular aging scripts differ individually

Aging does not appear to follow the same molecular script for everyone, according to an eight-year study of 335 women.

3 Sep 2026

Alpha-1 antitrypsin identified as potential target for preventing spontaneous preterm birth

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth.

3 Sep 2026

Microscopic peptide droplets reduce colorectal tumor growth in mice

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed microscopic peptide droplets that deliver large amounts of gene-silencing molecules into cancer and immune cells, reducing the growth of hard-to-treat colorectal tumours by about 67 per cent in mice.

3 Sep 2026

Biodegradable 'nanobone' material helps body regrow jawbone

For children born with cleft lip and palate, repairing gaps in the jawbone often means waiting until they are 10 to 12 years old before undergoing invasive bone graft surgery.

3 Sep 2026

Cancer drug eliminates HIV-infected cells in animal model study

Emory University researchers have provided the first proof-of-concept in a nonhuman primate model for eliminating HIV-infected cells with venetoclax, a clinically approved medication for cancer.

3 Sep 2026