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New AI model detects hidden antibiotic resistance genes beyond standard databases

resLens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

25 May 2026

Silica nanoparticles dampen early allergy signals in mouse mast cells

This in vitro study found that negatively charged SiO2 nanoparticles suppressed antigen-induced degranulation and activation-marker changes in IgE-sensitized mouse bone marrow-derived mast cells. By contrast, mTiO2 nanoparticles showed cytotoxic and pro-inflammatory effects, including enhanced DNP-induced IL-6 release, suggesting nanoparticle composition can shape early allergic immune responses.

24 May 2026

Scientists reveal why common pancreatic precancer lesions rarely turn deadly

Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like molecular features, while their surrounding stromal and immune environment remains closer to normal pancreatic tissue. The findings suggest that delayed or incomplete microenvironmental reprogramming may help explain why most PanIN lesions remain indolent rather than progressing to pancreatic cancer.

24 May 2026

CDC report reveals what 24 years of nutrition biomarkers say about America’s health

The 2026 CDC Nutrition Report will make nearly 24 years of NHANES biomarker data easier to use, covering up to 131 nutritional biomarkers in the US population aged 1 year and older. By standardizing blood and urine biomarker trends, demographic patterns, and comparisons of supplement use, the report aims to support nutrition policy, clinical reference intervals, and public health monitoring.

24 May 2026

Blood carotenoids offer the clearest signal of fruit and vegetable eating habits

The review finds that several candidate biomarkers may help estimate fruit and vegetable intake more objectively than self-reported dietary tools, but most remain limited by specificity, sampling burden, supplement use, or incomplete validation. Blood and skin carotenoids appear strongest for habitual intake, while vitamin C, folate, urinary flavonoids, hippuric acid, and potassium may be more useful for short-term intake or intervention adherence.

24 May 2026

RNA regulator RBM15 linked to immunity, metabolism, and cancer progression

A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including cancer, metabolic disorders, and cardiovascular conditions.

24 May 2026

Efferocytosis plays central role in wound healing and tissue repair

A new review shines a spotlight on efferocytosis, a critical biological process responsible for the removal of dead cells, as a central force in promoting efficient wound repair and maintaining tissue balance.

24 May 2026

DNA methylation variability may improve precision cancer treatment strategies

A new review article brings attention to the critical role of DNA methylation heterogeneity in shaping the tumor microenvironment, highlighting its growing importance in understanding cancer progression and advancing more precise treatment strategies.

24 May 2026

DNA repair gene variations reveal evolutionary roots of cancer susceptibility

A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased cancer susceptibility.

24 May 2026

Extrachromosomal circular DNA shows promise for precision disease diagnostics

A new scientific focus on extrachromosomal circular DNA (eccDNA) is opening transformative possibilities for disease detection, monitoring, and personalized medicine.

24 May 2026

Long non-coding RNAs regulate natural killer cell immune responses

A new review article highlights the powerful influence of long non-coding RNAs (lncRNAs) in regulating natural killer (NK) cells, revealing promising opportunities to enhance immune responses and improve treatment strategies across multiple diseases.

24 May 2026

Immunoproteasome plays emerging role in diabetes and metabolic complications

A newly published review article highlights the emerging importance of the immunoproteasome in the development and progression of diabetes and its wide-ranging complications, offering fresh perspectives on future therapeutic strategies.

24 May 2026

RNA modifications shape gut immunity and intestinal macrophage function

A new perspective on gut immunity is highlighting the powerful role of RNA modifications in shaping how the body maintains balance in the digestive system.

24 May 2026

RNA regulator YTHDF2 plays key role in controlling inflammation

A new review highlights the emerging importance of YTHDF2, a key regulator of RNA activity, in shaping the body's inflammatory responses and influencing a wide range of diseases.

24 May 2026

New computational pipeline improves effectiveness of pan-Ebola neutralizing antibodies

A team led by Professor Wei Yang at the National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, has developed a computational-experimental pipeline that synergistically optimizes antibody framework regions (FR) and complementarity-determining regions (CDR).

24 May 2026

How social media, AI, and surveillance can become health determinants

Digital technologies increasingly shape health by mediating how social, political, commercial, and economic conditions affect people’s lives. This Perspective calls for global collaboration to ensure digital transformation promotes health equity rather than reinforcing existing inequities.

24 May 2026