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Study identifies TAK1 gene as a key brake on cancer immunotherapy

Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.

19 Dec 2025

New genetic insights could lead to treatments for Candida auris

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

19 Dec 2025

Blocking platelet-activating factor reduces liver damage in cirrhosis

Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis.

19 Dec 2025

Researchers provide a global catalog of human pluripotent stem cell lines for clinical use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

18 Dec 2025

Phages use small RNA to hijack bacterial cells and boost replication

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

18 Dec 2025

Ants show new promise as a source of powerful antibiotics

Has a crucial component to the development of human medicine been hiding under our feet?

18 Dec 2025

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Lung immune cells switch roles to drive allergic inflammation

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune responses.

18 Dec 2025

New breakthrough expands possibilities for PET imaging

Imagine being able to watch organs and tissues work in real time. That's the power of Positron Emission Tomography, or PET imaging, a technology that gives physicians and researchers a window into cellular processes.

18 Dec 2025

Researchers point to mitochondria as a missing link between mental health and brain function

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

18 Dec 2025

New nanoparticle vaccines show promise against multiple deadly filoviruses

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.

18 Dec 2025

Everyday light exposure shapes how alert and mentally sharp we feel outside the lab

This real-world study shows that recent and habitual light exposure are linked to lower subjective sleepiness and faster reaction times in daily life. Brighter and more stable daytime light patterns were associated with better performance on specific cognitive tasks, independent of sleep and time of day.

18 Dec 2025

Study finds a new protein target against KRAS-driven non-small cell lung cancer

Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States.

18 Dec 2025

Large-scale study reveals joint functional and structural patterns of brain aging

Healthy aging induces parallel changes in brain functional activity and structural morphology, yet the interplay between these changes remains unclear.

18 Dec 2025

Advances in hemophilia gene therapy bring hope for pediatric patients

In the past three years, gene therapy has reshaped what's possible in hemophilia treatment for patients 18 and older. But a key question remains: How soon will these advances reach children?

18 Dec 2025

Gestational diabetes alters the placenta at the molecular level, study reveals

Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

18 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025