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PhoreMost announces lead oncology program and appoints Chief Medical Officer to support clinical entry

PhoreMost Limited, a biotech company focused on turning scientific breakthroughs into life-changing cancer drugs, today announced its lead program, PMC-001, a next-generation, small molecule microtubule targeting agent (MTA) for primary and secondary brain cancers.

From PhoreMost 12 Jun 2026

Leading AI models ace many vaccine questions but falter on clinical rules

A multilingual benchmark of 1,886 vaccine-related questions found that large language models answered most items accurately across English, Spanish, and Chinese. However, performance varied by vaccine type, language, and prompting method, with persistent errors in dosing, contraindications, age eligibility, and other clinically sensitive guidance.

11 Jun 2026

ChatGPT fills gaps like a confabulator, not a hallucinating mind

A Perspective article argues that large language model errors more closely resemble confabulations, while speech recognition errors, such as unsupported Whisper transcriptions, are functionally closer to hallucinations. The authors stress that these parallels are behavioral and provisional, not evidence of shared consciousness, and suggest that psychiatric concepts could help improve AI reliability.

11 Jun 2026

Scientists uncover protein-folding mechanism linked to diabetes progression

Origami masters turn simple sheets of paper into ornate sculptures. In the origami of life, our cells must fold proteins into specific three-dimensional shapes before they can carry out their biological jobs.

11 Jun 2026

The cerebellum may help aging brains stay sharper

A large MRI study of more than 47,000 adults found that cerebellar aging is uneven, with posterior association regions and some motor-related areas showing steeper age-related changes. Larger cerebellar volumes were linked to better cognitive performance, supporting a threshold-reserve model in which the cerebellum may help sustain cognition before Alzheimer’s pathology becomes widespread.

11 Jun 2026

AI breakthrough accelerates molecular simulations for drug discovery

A new AI model has become so good at predicting how molecules evolve over time that, in the future, it could speed up the costly and time-consuming process of testing new drugs.

11 Jun 2026

Trial finds prunes do not outperform calcium and vitamin D for male bone density

A one-year randomized trial found that daily prune supplementation did not improve total or lumbar spine bone mineral density in older men susceptible to, or with, osteopenia. Although some bone turnover biomarkers differed between prune and control groups, these changes did not translate into measurable bone density benefits beyond calcium and vitamin D3 supplementation.

11 Jun 2026

Increased stress, reduced sleep alter brain structure and function in children

A new study suggests that variables linked to socioeconomic status (SES) – such as increased stress and reduced sleep – have strong relationships to brain structure and function in children.

11 Jun 2026

Interspecies blastocyst complementation generates generates rat-derived kidneys in mice

Kidney transplantation remains the most effective treatment for end-stage kidney disease, yet a severe shortage of donor organs continues to limit access for millions of patients worldwide.

11 Jun 2026

Brain histamine neurons control moment-to-moment memory accessibility

The same memory can feel vivid and accessible one moment, yet stubbornly out of reach the next - even when the memory itself remains intact.

11 Jun 2026

Amsterdam UMC researchers overturn long-standing biological pacemaker dogma

Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field.

11 Jun 2026

Researchers discover 45 new toxins produced by Salmonella bacteria

Researchers at the University of São Paulo (USP) in Brazil have discovered 45 new toxins produced by Salmonella bacteria, some of which are associated with foodborne infections.

11 Jun 2026

Review uses evolutionary lens to examine modern human aging rates

A review article now published in "Nature Reviews Genetics" brings together evolutionary theory, comparative genomics and large-scale human genetics to explain why we age and why aging rates differ among individuals and species.

11 Jun 2026

Circadian clock protein BMAL1 enhances inflammatory responses in immune cells

Daily life is shaped by the solar day, influencing when we wake up, eat, work, and sleep. Inside the body, a similar internal timing system -present in nearly every cell- known as the circadian clock, synchronizes many biological functions such as sleep, metabolism, hormone release, and even the immune system's activity.

11 Jun 2026

Genetic screening of LOXHD1 variants guides early hearing loss intervention

Hearing loss is a common cause of disability worldwide, with anywhere between 30-60% of cases being caused by genetic factors. LOXHD1 is a gene integral to essential protein interactions responsible for maintaining normal hair cell function.

11 Jun 2026

Experts propose unified framework to advance the future of high-altitude medicine

As increasing numbers of people live, work, and travel at high altitudes, experts are calling for a major shift in how altitude-related health conditions are understood, diagnosed, and treated.

11 Jun 2026

Gut bacterial molecule reduces intestinal inflammation by slowing cell energy

Enterobactin, a molecule produced by gut bacteria, may hold a surprising key to reducing intestinal inflammation. Not by attacking the immune system directly, but by temporarily slowing down the cell's own energy production.

11 Jun 2026

Stretchable wound zipper controlled by smartphone app accelerates skin healing

Skin is our protective barrier from the outside world, and it is highly susceptible to damage. To prevent infection, restore protective skin cells, and reduce scarring, it is essential to quickly and robustly close a wound.

11 Jun 2026

New treatment platform delivers full-length mRNA for Duchenne muscular dystrophy

A new treatment platform developed by researchers at The University of Texas MD Anderson Cancer Center was able to deliver messenger RNA (mRNA) of the full-length DMD gene into preclinical models of Duchenne muscular dystrophy, successfully restoring the production of an important muscle protein, dystrophin, and dramatically improving muscle strength, endurance and function in vivo.

11 Jun 2026

Teenage risk-taking linked to lower baseline dopamine levels

Teenage risk-taking, such as experimentation with alcohol, cannabis, nicotine and other substances, may reflect a compensatory response to lower baseline dopamine, the brain chemical for reward activity, suggests a new University of Pittsburgh School of Medicine study, published today in Nature Communications.

11 Jun 2026