Medical Science News

RSS

Spatial arrangement of inhibitory connections shapes brain network criticality

In neuroscience, the brain criticality hypothesis proposes that neurons in the brain are arranged in such a way that neural activity lies at or near a transition point between two extremes: an ordered state where neural activity dies out quickly and a disordered state where neural activity tends to spread quickly and potentially grow uncontrollably.

13 Nov 2026

Blocking a specific protein prevents severe heart failure in mice

Most heart failure cases are caused to a large degree by a build-up of excess scar tissue in the heart, which currently has no treatments.

13 Nov 2026

14 million sleep records expose the social divide in sleep

More favorable social conditions are associated with steadier, longer sleep, according to long-term Fitbit data from the All of Us Research Program.

13 Nov 2026

Aging reduces the brain's waste-flushing process during sleep

As people age, they may sleep for shorter periods and wake up more frequently during the night. In addition to those disruptions, MIT researchers have now discovered that a process responsible for flushing waste from the brain during sleep is commonly impaired in older people.

13 Nov 2026

Broad genomic sequencing extends survival in advanced lung cancer patients

New research in the November 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network found that patients with advanced non-small cell lung cancer (NSCLC) lived longer when they received broad-based genomic sequencing (BGS)-testing a large panel of dozens or hundreds of genes at once-before starting treatment, compared with patients who received more limited biomarker testing of just one or two genes.

13 Nov 2026

DNA methylation profiling stratifies recurrence risk in low-grade endometrial cancer

Molecular diagnostic approaches are expanding what information is available for clinicians and laboratory professionals, including uncovering antimicrobial resistance, identifying pathogens missed by conventional methods, revealing cancer recurrence risks and characterizing complex tumor biology.

13 Nov 2026

Scientists unveil first comprehensive atlas of basal ganglia cell types

Capturing a complete picture of what causes brain diseases from schizophrenia and Parkinson's disease to addiction has long remained a challenge to scientists.

12 Nov 2026

Placental stem cell therapy shows promise for diabetic foot ulcers

An experimental cell therapy was well tolerated in 10 people with chronic diabetic foot ulcers, according to first-in-human study led by researchers at Wake Forest Institute for Regenerative Medicine (WFIRM).

12 Nov 2026

Blocking Granzyme K protein may protect organs from age-related damage

Monash University researchers have identified a protein that drives age-related damage in vital organs, opening a potential new avenue for treatments that could help people stay healthier as they get older.

12 Nov 2026

Human heart tissue model offers insights into inherited cardiomyopathy

Inherited cardiomyopathies - diseases of the heart muscle, which cause the heart to have a harder time pumping blood to the rest of the body - are the leading cause of heart failure in young adults.

12 Nov 2026

Your fitness may say less about cellular aging than you think

In a study of 84 middle-aged adults, researchers found that higher perceived stress and older age were associated with shorter telomeres, while physical fitness, body composition, and lifestyle habits showed no consistent independent associations. The findings suggest that telomere length may reflect psychosocial and health-related burden more closely than current physical performance, although the reported chronic disease association requires clarification because of an inconsistency in the paper's statistical coding.

12 Nov 2026

Scientists identify metabolic pathway driving lung cancer lymph node metastasis

Metabolic reprogramming plays a critical role in shaping the adaptive capabilities of malignant cells during dissemination.

12 Nov 2026

New light-based tool reveals how cells regulate autophagy

Inside each cell is a dynamic world of molecules and chemicals, signals and receivers, and construction and destruction.

12 Nov 2026

Liver-derived protein helps protect brain cells and improves memory in Alzheimer's mice

Researchers identified 92 circulating proteins that cross the blood-brain barrier and enter brain tissue, revealing how proteins such as liver-derived APOA1 help regulate astrocyte cholesterol metabolism and support neuronal synapses. In an Alzheimer's disease mouse model, APOA1 transport was impaired, but increasing its production in the liver reduced selected inflammatory and amyloid-related abnormalities, improved synaptic integrity, and enhanced some measures of memory.

12 Nov 2026

Inhaled living medicine reduces drug-resistant lung biofilms in the lungs of pigs

A "living medicine" has thinned biofilms of antibiotic-resistant Pseudomonas aeruginosa in the lungs of pigs, according to the findings of a study published today in the journal eBioMedicine.

12 Nov 2026

Sleep-like brain waves during wakefulness linked to Parkinson's symptoms

A new study shows that slow brain waves – typically associated with deep sleep or a sleep-like state – are more frequent during wakefulness in patients with Parkinson's disease and correlate with symptoms such as hallucinations and impaired cognition.

12 Nov 2026

Immune and metabolic shifts drive acute pancreatitis into chronic disease

Pancreatitis is clinically classified into acute pancreatitis (AP) and chronic pancreatitis (CP). Most patients with AP recover without residual pancreatic dysfunction; a subset develops recurrent AP, and only selected high-risk individuals-particularly those with ongoing etiological exposure, genetic susceptibility, or severe necrotizing disease-progress to CP.

12 Nov 2026

Extreme heat stops athletes from fully using carbohydrates for fuel

Endurance sport has seen a renaissance in the understanding of carbohydrates for fuel in recent years. Advances in sports science have led to much higher levels of carbohydrates either eaten or drunk during exercise, with some top sports stars consuming 120g or more per hour during a race.

12 Nov 2026

New salt-triggered gel makes bacterial cancer therapy much safer

The abdominal cavity is salty enough to set a gel. On that trick rests a delivery system reported in The Innovation: a small molecule that stays liquid in the syringe and, meeting sodium in the peritoneum, gels within a minute.

12 Nov 2026