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Expert guidelines for fungal endophthalmitis in the Asia-Pacific region

Fungal eye infections affect millions globally, with an especially high incidence in South and Southeast Asia.

1 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Killer T cell traits explain why some people achieve long-term HIV remission after treatment

Researchers led by a team from Mass General Brigham and the Ragon Institute have discovered why some people living with HIV who are given a treatment called broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop taking standard, lifelong HIV medications and maintain control of the virus for years, while others given the same treatment do not achieve this remission.

1 Dec 2025

Maternal exposure to fatty food aromas predisposes offspring to obesity

A research team at the Max Planck Institute for Metabolism Research has found that the smell of fatty foods during pregnancy increases the risk of overweight and obesity in children.

1 Dec 2025

Researchers uncover GFAP’s role in mitochondrial dysfunction

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

1 Dec 2025

Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

1 Dec 2025

Circadian rhythms can influence outcomes related to influenza infections

Researchers at Children's Hospital of Philadelphia (CHOP) found that circadian rhythms – the biological clocks of the body – can influence outcomes related to influenza infections, providing clinicians with insight about how biological processes can be used to optimize care for critically ill patients with respiratory viral infections.

1 Dec 2025

Epstein family support accelerates USC’s mission to end Alzheimer’s

The USC Alzheimer's Therapeutic Research Institute will be renamed the USC Epstein Family Alzheimer's Therapeutic Research Institute in honor of Life Trustee Daniel J. Epstein '62, his wife Phyllis and their family, who have been the philanthropic leaders behind the university's world-leading efforts to make Alzheimer's a memory.

1 Dec 2025

Mapping SV2A drug binding offers a path to better epilepsy treatments

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

1 Dec 2025

UTEP scientists find promising new target in the fight against high-grade serous carcinoma

Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer.

1 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025