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Oral molecule prevents kidney stones and restores survival in mice

Scientists at the Buck Institute for Research on Aging have shown that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones, protect against kidney failure, and fully restore normal survival in a mouse model of Primary Hyperoxaluria Type 2 (PH2), a rare and currently untreatable genetic disorder that causes progressive kidney failure in infants and young adults.

2 Apr 2026

Ultrasound enables real-time monitoring and treatment of tumor vasculature

Announcing a new article publication in BIO Integration. The tumor vasculature, characterized by pathological angiogenesis and structural abnormalities, drives the progression of solid tumors by inducing hypoxia-acidosis microenvironments and therapeutic resistance.

2 Apr 2026

Regulatory T cells may influence inflammation and behavior in autism

Two new studies from the UC Davis MIND Institute examined regulatory T cells (Tregs) and their potential role in neuroinflammation and behavioral changes associated with autism.

2 Apr 2026

Moderate wine intake tied to slower biological aging in men

Researchers studying 22,495 adults in Southern Italy found that men with moderate wine intake in the traditional Mediterranean diet range showed slightly slower biomarker-based biological aging, with the lowest estimated aging signal at about 170 mL per day. The study also found that overall ethanol intake did not show the same moderate-level pattern, and higher total alcohol intake was linked to faster biological aging in dose-response analyses.

2 Apr 2026

Obesity, sleep, smoking, and inactivity show the strongest links to hypertension in U.S. adults

A cross-sectional analysis of 20,912 U.S. adults found that obesity, overweight, inadequate physical activity, smoking, and short or long sleep were each associated with higher odds of hypertension, while overall diet quality by HEI-2015 was not significantly associated. Sleep associations differed by sex, and lower sodium intake remained linked to lower odds of hypertension in sensitivity analyses.

2 Apr 2026

NCCN grants funding to five oncology leaders of the future

The National Comprehensive Cancer Network® (NCCN®)-an alliance of leading cancer centers-announces the 2026 recipients for the annual NCCN Foundation® Young Investigator Awards.

2 Apr 2026

Blood-based test could personalize treatment for patients with HPV-associated throat cancer

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer.

2 Apr 2026

New drying technique stabilizes vital vaccines at room temperature

A significant challenge in global healthcare and biotechnology is the "cold chain"-the network of refrigerated storage and transport required to keep protein-based drugs, vaccines, and diagnostic tests from degrading.

2 Apr 2026

Study introduces biomarker to characterize aggressiveness of brain tumors

Researchers from the Biomedical Data Science Laboratory (BDSLab) at the ITACA Institute of the Universitat Politècnica de València have developed a new method based on magnetic resonance imaging that enables objective quantification of the growth of the most aggressive brain tumours, particularly glioblastoma.

2 Apr 2026

Occasional heavy drinking poses major risk to liver health

People may assume that if they drink lightly during the week or month, heavy drinking on the occasional Friday or Saturday may not cause their liver harm.

2 Apr 2026

Researchers settle 60-year debate on the fundamental mechanisms of visual perception

A scientific dispute spanning six decades about fundamental mechanisms of visual perception in mammals has now been settled. Researchers at TUM have succeeded in observing the visual information flow from neuron to neuron.

2 Apr 2026

Researchers discover new virulence regulator of diarrheal pathogen

Pathogenic bacteria often delay the activation of their virulence program until they are inside the host. Researchers have identified a new mechanism that controls this process.

2 Apr 2026

AI-powered portable eye scanner makes vision screenings more accessible

Imagine being able to assess how healthy the front of our eyes are not only in hospitals, but also in remote eye-screening camps, elderly-care facilities, pharmacies, or even train stations.

2 Apr 2026

Bedfont® becomes the first compassionate workplace accredited in Kent

Bedfont® Scientific Ltd. is a world leader in breath analysis, with over 49 years of expertise in designing and manufacturing medical devices.

From Bedfont® Scientific Ltd 2 Apr 2026

New method improves reliability of protein language model predictions

AI language models, used to generate human-like text to power chatbots and create content, are also revolutionizing biology by treating complex biological data like a language.

1 Apr 2026

New wearable detects fatigue accurately using AI and advanced sensors

Burnout and chronic fatigue carry a substantial economic cost and pose serious risks in professions where alertness is critical.

1 Apr 2026

New brain circuit discovery offers hope for chronic pain treatment

A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for the roughly 60 million Americans living with persistent pain, according to a study published in Nature.

1 Apr 2026

AEGIS tool helps scientists study evolution of aging and lifespan

Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena have developed AEGIS, a freely available software tool that enables scientists to simulate evolution on a standard computer and investigate how lifespan and aging evolve under different ecological pressures and genetic constraints.

1 Apr 2026

Vitamin D levels in midlife tied to lower dementia risk marker

Having higher levels of vitamin D in the blood in middle age is associated with lower levels of tau protein in the brain, which is a sign of dementia, years later, according to a study published April 1, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

1 Apr 2026

Heat-activated patch shows promise for noninvasive melanoma treatment

Melanoma is a deadly form of skin cancer that is typically removed surgically. Now, researchers publishing in ACS Nano report they have developed a potential noninvasive treatment for melanoma in the form of a stretchy, heat-activated patch similar to a bandage.

1 Apr 2026