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Whole-genome sequencing improves PARP inhibitor treatment prediction

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

12 Jan 2026

ALS breakthrough: Restoring protein production in motor neuron axons

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

12 Jan 2026

Heavy coffee drinking may weaken bone density in older women

Researchers investigate the longitudinal associations of coffee and tea consumption with bone mineral density in older women.

12 Jan 2026

Chronic back pain predicts poor sleep in older men

Researchers investigate the prevalence of back pain and sleep issues in men 65 years of age and older.

12 Jan 2026

How pandemic viruses spread across U.S. cities before anyone notices

Researchers reconstruct the spatial spread of pandemic respiratory viruses across metropolitan areas throughout the United States

12 Jan 2026

Struggling to make ends meet may slow brain development in infants

Researchers identify specific psychosocial factors that strongly correlate with altered brain development within the first year of life.

12 Jan 2026

Study uncovers a neural brake that limits motivation during unpleasant situations

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

9 Jan 2026

Ultrasound-responsive nanocatchers enable precise in-situ tumor antigen capture

Professor Zhaohui Tang and Associate Professor Zhilin Liu from the team of Professor Xuesi Chen at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed ultrasound-responsive in-situ antigen nanocatchers (S-nanocatchers), achieving precise spatiotemporal capture of tumor antigens and controllable acquisition of in-situ vaccines.

9 Jan 2026

Study reveals how tuberculosis exploits immune defenses to promote infection

Scientists have made a discovery that helps explain why humans and animals are so susceptible to contracting tuberculosis(TB) – and it involves the bacteria harnessing part of the immune system meant to protect against infection.

9 Jan 2026

Scientists identify a molecular switch that controls water flow in the gut

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

9 Jan 2026

Brain signals shape facial expressions before movement begins

Every time we smile, grimace, or flash a quick look of surprise, it feels effortless, but the brain is quietly coordinating an intricate performance.

9 Jan 2026

SPINECRAFT: Engineering a 4D human spinal cord for disease research

Zaida Álvarez Pinto, Principal Investigator at the Institute for Bioengineering of Catalonia (IBEC), has been awarded an ERC Consolidator Grant, one of the most prestigious and competitive sources of funding in the European Union.

9 Jan 2026

Pancreatic organoid study reveals key factors shaping complex lumen formation

Organs often have fluid-filled spaces called lumens, which are crucial for organ function and serve as transport and delivery networks.

9 Jan 2026

Fish study reveals how ovulation triggers sexual receptivity in females

A research team led by Hiroshima University and Tokyo University of Agriculture and Technology have proposed a neuroendocrine mechanism in bony fish that signals ovulation from the ovaries to the brain, using the medaka fish as a model; the first step to elucidate the neural circuits for facilitation of sexual receptivity in female teleosts.

9 Jan 2026

Non-coding RNA mutations unveiled as new cause of retinitis pigmentosa

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as daylight-sensing photoreceptor cells in the retina gradually die, potentially leading to blindness over time.

9 Jan 2026

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Bacterial communities in colorectal cancer reveal patterns linked to tumor genetics and patient outcomes, paving the way for personalized treatment strategies.

From BGI Genomics 9 Jan 2026

New method measures how effectively antibiotics kill bacteria

Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions.

9 Jan 2026

UCLA awarded major state funding to advance comprehensive cannabis research

UCLA has received four grants totaling $7.3 million from the California Department of Cannabis Control (DCC) to support research on a broad range of topics, from the therapeutic potential of cannabinoids to the cardiovascular risks of cannabis use and strategies for addressing California's unregulated cannabis market.

8 Jan 2026

$Neural pain pathways found to play crucial role in bone fracture healing$

Neural pain pathways found to play crucial role in bone fracture healing

When a house catches on fire, we assume that a smoke alarm inside will serve one purpose and one purpose only: warn the occupants of danger.

8 Jan 2026

Study reveals innate immune barriers to long-term pig kidney transplant survival

Pioneering research led by Brazilians describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant.

8 Jan 2026