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Small T-cell subset drives powerful multiple myeloma immunotherapy responses

Researchers from The University of Osaka find that only a small fraction of T cells may drive the robust anti-cancer response seen in breakthrough multiple myeloma immunotherapy.

21 May 2026

Bioluminescent fungi reveal pathways for advanced biotechnology and medical applications

Like fireflies and many deep-sea creatures, certain fungi can naturally emit light through bioluminescence pathways in which specialized enzymes convert chemical energy into visible light.

21 May 2026

Light-driven nanomotors improve multimodal breast cancer treatment efficacy

The nanomotor starts with bowl‑shaped mesoporous polydopamine (PDA) nanoparticles. These biocompatible bowls are loaded with two key payloads: Fe(II) ions as a Fenton catalyst, and BNN6, a thermally sensitive NO donor.

21 May 2026

Polymer-based immunotherapies enhance tumor targeting and immune activation

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

GLP-1 drugs may help curb addiction by targeting reward pathways

GLP-1 receptor agonists, already used for Type 2 diabetes and obesity, show promise in reducing alcohol and drug-seeking behaviors through central reward and dopamine-related pathways. Most evidence remains preclinical, with limited early human data, so larger clinical trials are needed before these drugs can be recommended for addiction treatment.

21 May 2026

AI passed a classic Turing test by mastering the art of human small talk

In a standard three-party Turing test, persona-prompted LLMs were often judged to be human, with GPT-4.5 selected over real people 73% of the time in 5-minute trials. The findings suggest that short human-AI interactions now hinge less on factual intelligence and more on social style, conversational flow, and humanlike persona cues.

20 May 2026

How an AI system learned to write expert-level scientific code

ERA is an AI system that uses large language models and tree search to automatically write, test, and refine scientific software for measurable research tasks. Across bioinformatics, COVID-19 forecasting, time-series analysis, geospatial modeling, neuroscience, and numerical computation, ERA produced expert-level solutions that often surpassed established human-developed methods.

20 May 2026

Minimal exposure to modern medicine rapidly alters the human microbiome

Even minimal exposure to modern medicine can rapidly change the human microbiome. In a new study publishing May 20 in the Cell Press journal Cell Reports, researchers reveal that the gut microbes of remote Amazonian Indigenous communities began shifting toward patterns more commonly seen in urban, industrialized populations after only a few medical visits.

20 May 2026

Brain cell division errors may drive cancer and developmental disorders

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells.

20 May 2026

ChatCPR instructor delivers near-perfect CPR guidance in proof-of-concept study

A proof-of-concept JAMA Internal Medicine study found that widely available AI models could deliver many guideline-concordant CPR instructions in simulated out-of-hospital cardiac arrest scenarios. A purpose-built AI agent, ChatCPR, achieved higher checklist-based adherence than baseline AI models and dispatcher-assisted CPR instructions, but prospective real-world validation is still needed.

20 May 2026

Cytokine-armored CAR-T cell therapy successfully attacks aggressive brain tumors in mice

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy that helps the immune system better attack aggressive brain tumors in mice while reducing dangerous side effects that have long limited immune-based treatments for glioblastoma, one of the deadliest and most treatment-resistant brain cancers.

20 May 2026

Scientists link schizophrenia risk gene to early cortical neuron changes

Researchers at King's College London have identified the biological nature and timing of changes in human cortical neurons caused by altering activity of a schizophrenia-associated gene in developing human neurons.

20 May 2026

Restoring ADAR2 enzyme reduces metastatic spread in osteosarcoma

Osteosarcoma is the most common primary bone cancer in children, adolescents, and young adults. Although chemotherapy and surgery have improved survival for localized disease, outcomes remain poor when tumors spread to the lungs or return after treatment.

20 May 2026

Longevity science and public health must unite for aging populations

A new editorial was published in Volume 18 of Aging-US on May 18, 2026, titled "Public health in the age of longevity interventions: from prevention to system-wide resilience."

20 May 2026

Tumor microenvironment markers forecast immunotherapy response in rare cancers

A new study in Cell Reports Medicine from researchers at The University of Texas MD Anderson Cancer Center identified key features that may help predict which types of rare cancers are likely to respond to immunotherapy.

20 May 2026

Real-time memory tests identify alcohol-induced blackouts as they happen

It's not surprising if someone experiences memory loss, or a 'blackout,' while drinking alcohol. While common, blackouts are considered a public health concern linked to injury, arrest, assault and overdose.

20 May 2026

Fluid viscosity drives mechanical memory and invasion in glioblastoma

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention.

20 May 2026

Plant-based eye drops harness photosynthesis to heal dry eyes

What if your eyes could use light to heal themselves? Drawing inspiration from how plants harness sunlight, researchers at the National University of Singapore (NUS) are pioneering a revolutionary treatment for dry eye disease.

20 May 2026

Engineered nanomaterials optimize delivery barriers in cancer immunotherapy

Cancer immunotherapy works by mobilizing the body's own immune system to recognize and destroy malignant cells.

20 May 2026

Spatial modeling of tissue compartments predicts breast cancer treatment response

HER2-positive breast cancer accounts for about 20% of breast cancer cases and is generally associated with more aggressive behavior and a higher risk of distant metastasis, while pathologic complete response (pCR) after neoadjuvant chemotherapy is strongly linked to better survival outcomes.

20 May 2026