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Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Global study suggests potential for universal vaccine against Haemophilus influenzae

A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

31 Oct 2025

Common viruses sharply raise heart attack and stroke risk, major global review shows

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

30 Oct 2025

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances genome stability even in human cells, revealing a potential pathway to strengthen DNA repair and slow aging.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.

30 Oct 2025

Study uncovers neural mechanisms behind memory stabilization

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers.

30 Oct 2025

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

30 Oct 2025

New method yields up to twice as many therapeutic myogenic cells as previous protocols

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

30 Oct 2025

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

30 Oct 2025

Minimal fibers enable communication between brain hemispheres

Just a few fibers are enough for the two hemispheres of the brain to communicate with each other. This was shown by a new international study led by Professor Dr Michael Miller (University of California, Santa Barbara) and Professor Dr Lukas J. Volz (Department of Neurology at University Hospital Cologne and the University of Cologne's Faculty of Medicine) in close collaboration with Professor Dr Christian Bien's team at the Bethel Epilepsy Centre (University Hospital OWL at Bielefeld University).

30 Oct 2025

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and the Eötvös Loránd University in Budapest has developed a groundbreaking new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies.

30 Oct 2025

Global Virus Network announces the addition of three new Centers of Excellence

The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, today announced the addition of three new Centers of Excellence: the USF Health Institute for Translational Virology and Innovation at the University of South Florida (USF) in Tampa, Florida, USA, the Department of Microbiology, Immunology and Parasitology at the Federal University of São Paulo (UNIFESP) in Brazil, and the Pathogen Research Centre (PaRC) at Western University in Canada.

30 Oct 2025

Liver alterations associated with MASLD can directly affect the brain and behavior

A multidisciplinary research team has discovered that liver alterations associated with metabolic dysfunction-associated fatty liver disease (MASLD) can directly cause cognitive and neurological impairments, and that these effects can be reversed by a therapy exclusively targeting the liver.

30 Oct 2025

Medical Science News

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

Global study suggests potential for universal vaccine against Haemophilus influenzae

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Massive cross-ancestry study explains why obesity risks differ around the world

Common viruses sharply raise heart attack and stroke risk, major global review shows

Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging

Study confirms PSA screening improves survival and safety

Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance

Study uncovers neural mechanisms behind memory stabilization

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

New method yields up to twice as many therapeutic myogenic cells as previous protocols

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

Minimal fibers enable communication between brain hemispheres

New chemotherapeutic agent shows remarkable efficacy against multiple tumor types

Global Virus Network announces the addition of three new Centers of Excellence

Liver alterations associated with MASLD can directly affect the brain and behavior

Sharing happy moments with a partner may be good for older people's health

Integrating physicochemical laws into future AI models for better drug design

Understanding the role of m6A methylation in acute lung injury pathogenesis

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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