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Experimental antiviral prevents MERS-CoV in rhesus macaques

The experimental antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV), according to a new study from National Institutes of Health scientists.

13 Feb 2020

Inflammation detected in the brains of veterans with Gulf War Illness

In a new discovery, researchers at Massachusetts General Hospital have detected widespread inflammation in the brains of veterans diagnosed with Gulf War Illness.

13 Feb 2020

Trinity bioengineers take crucial step towards mending a broken heart

Bioengineers from Trinity College Dublin, Ireland, have developed a prototype patch that does the same job as crucial aspects of heart tissue.

13 Feb 2020

The wealthier you are, the more food you waste

A new study revealed that every person in the world is wasting about 500 calories of food a day, which is equivalent to one McDonald’s Big Mac, and the wealthiest people are the worst in wasting food.

13 Feb 2020

'Smart' bandages could facilitate healing of hard-to-treat wounds

Chronic and non-healing wounds--one of the most devastating complications of diabetes and the leading cause of limb amputation--affects millions of Americans each year. Due to the complex nature of these wounds, proper clinical treatment has been limited.

13 Feb 2020

Improving ability to predict autism risk with few drops of blood

Within days of birth, a few drops of blood are collected from every newborn in California--and across the United States -- which are then stored on filter paper and screened for dozens of genetic and congenital disorders, such as phenylketonuria, an inherited metabolic disorder that can result in intellectual disability, seizures, heart and behavioral problems.

13 Feb 2020

Neuronal necrosis occurs much earlier in Alzheimer’s disease progression than previously thought

Alzheimer's remains the leading cause of dementia in Western societies, with some estimates suggesting that as many as 24 million people worldwide are living with the disease.

13 Feb 2020

Circulating ceramide ratios may be useful predictors of future dementia risk

Novel blood-based biomarkers for dementia could identify disease at an early preclinical stage, serve as surrogate outcomes for clinical trials of investigational therapies and even identify future potential therapeutic targets.

13 Feb 2020

Researchers investigate how early life trauma contributes to functional neurological disorder

In individuals with functional neurological disorder, the brain generally appears structurally normal on clinical MRI scans but functions incorrectly (akin to a computer software crashing), resulting in patients experiencing symptoms including limb weakness, tremor, gait abnormalities and non-epileptic seizures.

13 Feb 2020

Targeting one's internal clock could prevent or slow breast cancer progression

City of Hope scientists have identified an unlikely way to potentially prevent or slow the progression of aggressive breast cancer: target one's internal clock.

13 Feb 2020

Autophagy genes work against tumors in some ovarian cancers

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina and University of California at San Diego published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.

13 Feb 2020

Kisspeptin can boost human attraction brain pathways, study shows

The researchers behind the early-stage work, published in JCI Insight, are exploring whether kisspeptin can ultimately be used to treat men with common psychosexual disorders - sexual problems which are psychological in origin such as low libido.

13 Feb 2020

Bilingualism can delay symptoms of dementia, study reveals

A study by York University psychology researchers provides new evidence that bilingualism can delay symptoms of dementia.

13 Feb 2020

Moffitt research may provide a path toward improved multi-drug adaptive therapies

Personalized cancer treatments have greatly improved the lives of patients; however, many eventually develop resistance to these targeted drugs.

13 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

A143T variant of the GLA gene likely to cause late-onset Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study.

13 Feb 2020

Surprising discovery about childhood brain tumor may unlock new cancer treatments

A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer and, potentially, many others.

13 Feb 2020

Nutrition researcher shows how foods affect our hormones and health

Nutrition researcher and New York Times bestselling author Neal Barnard, MD, demonstrates how foods affect our hormones--and our health--in his new book, Your Body in Balance.

13 Feb 2020

Study tests hypothesis that empty SV40 capsids would improve sepsis outcomes

Numerous previous attempts to develop therapeutic treatments, directed at discreet targets of the sepsis cascade, could not cope with the complex pathophysiology of sepsis and failed.

13 Feb 2020

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progression, researchers from The University of Texas MD Anderson Cancer Center report in the journal Nature today.

13 Feb 2020