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Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Traumatic brain injury (TBI) remains one of the most pressing public health challenges, leaving millions with lasting disabilities each year.

12 Nov 2025

Researchers identify a protein vital to endothelial wound healing after surgery

Surgeons in the United States perform nearly 600,000 coronary artery stent procedures and bypass surgeries every year.

12 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Age and flu vaccine type influence immune activation

New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the vaccine type and age of the patient.

12 Nov 2025

LRIG1 could serve as important biomarker to distinguish between glioma types and grades

A new research paper was published in Oncotarget (Volume 16) on November 6, 2025, titled "LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas."

12 Nov 2025

Plant-based diet prevents and reverses heart microvascular dysfunction in hypertensive rats

Eating a plant-based diet consisting of fruits, vegetables, nuts and legumes can help prevent and reverse heart disease in rats that have high blood pressure, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

12 Nov 2025

Simple blood test may be a better guide treatment for ovarian cancer

More than 300,000 women are diagnosed with ovarian cancer globally each year.

12 Nov 2025

SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells

Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases.

12 Nov 2025

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

12 Nov 2025

Breakthrough ultrasound sensor opens new possibilities for wearable medical devices

Conventional wearable ultrasound sensors have been limited by low power output and poor structural stability, making them unsuitable for high-resolution imaging or therapeutic applications.

12 Nov 2025

Hormonal fluctuations shape learning through changes in dopamine signaling

Researchers have long established that hormones significantly affect the brain, creating changes in emotion, energy levels, and decision-making. However, the intricacies of these processes are not well understood.

11 Nov 2025

Utah researchers uncover microglia as key regulators of anxiety in the brain

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide.

11 Nov 2025

Artificial intelligence improves diagnosis of invisible airway blockages

Researchers at the University of Southampton have developed an artificial intelligence (AI) tool that can spot hard-to-see objects lodged in patients' airways better than expert radiologists.

11 Nov 2025

What makes truffles more than a delicacy? They’re packed with bioactive compounds

Italian researchers reviewed the chemical composition and biological potential of truffles, identifying them as rich sources of antioxidants, polysaccharides, sterols, and vitamins. The review highlights their promise as functional foods and natural therapeutics, while emphasizing the need for sustainable cultivation and clinical validation.

11 Nov 2025

Recreational athletes feel healthy but unhappy with their bodies

New research from Edith Cowan University (ECU) has revealed a striking disconnect between how recreational athletes perceive their health and fitness, and how they feel about their bodies.

11 Nov 2025

Scientists reveal mathematical law governing limits of biological growth

A research team including a scientist of Earth-Life Science Institute (ELSI) at Institute of Science Tokyo, Japan, has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant-a phenomenon known as "the law of diminishing returns."

11 Nov 2025

AI chat box helps investigate complex biology in English language

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

11 Nov 2025

Stress-induced neuron loss shown to disrupt blood flow and neural communication

While the exact causes of neurodegenerative brain diseases like Alzheimer's and dementia are still largely unknown, researchers have been able to identify a key characteristic in affected brains: reduced blood flow.

11 Nov 2025

Medical Science News

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Researchers identify a protein vital to endothelial wound healing after surgery

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Age and flu vaccine type influence immune activation

LRIG1 could serve as important biomarker to distinguish between glioma types and grades

Plant-based diet prevents and reverses heart microvascular dysfunction in hypertensive rats

Simple blood test may be a better guide treatment for ovarian cancer

SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

Breakthrough ultrasound sensor opens new possibilities for wearable medical devices

Hormonal fluctuations shape learning through changes in dopamine signaling

Utah researchers uncover microglia as key regulators of anxiety in the brain

Artificial intelligence improves diagnosis of invisible airway blockages

What makes truffles more than a delicacy? They’re packed with bioactive compounds

Recreational athletes feel healthy but unhappy with their bodies

Scientists reveal mathematical law governing limits of biological growth

AI chat box helps investigate complex biology in English language

Stress-induced neuron loss shown to disrupt blood flow and neural communication

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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