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Air pollution weakens the life-extending benefits of exercise

A study reveals that high PM2.5 levels reduce the health benefits of exercise, highlighting the need for air quality considerations in activity guidelines.

3 Dec 2025

New method reveals how human cells initiate DNA replication

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, and genetic disorders. Therefore, understanding how cells replicate their DNA is crucial for elucidating fundamental biological processes, diseases, and even evolution.

3 Dec 2025

Stem cells reshape in response to electrical signals, study reveals

Scientists in Melbourne have discovered how tiny electrical pulses can steer stem cells as they grow, opening the door to new improved ways of creating new tissues, organs, nerves and bones.

3 Dec 2025

DNA language model performance hinges on pre-training data choices

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models.

3 Dec 2025

Automated EHR system triages cancer symptoms, improves care team efficiency

For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.

3 Dec 2025

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

An updated Cochrane review has found that calcium supplementation has no effect on pre-eclampsia, challenging long-held assumptions about the role of calcium in preventing hypertensive disorders in pregnancy.

3 Dec 2025

Gene variant linked to higher risk of chronic rejection after lung transplant

About one third of lung transplant recipients have a genetic variant that makes them more likely to develop chronic lung allograft dysfunction (CLAD), the primary cause of mortality after lung transplantation.

2 Dec 2025

Rice researchers develop resettable serum markers for clearer brain activity signals

Tracking how genes switch on and off in the brain is essential for understanding many neurological diseases, yet the tools to monitor this activity are often invasive or unable to capture subtler changes over time.

2 Dec 2025

SCAI and CRT launch partnership to expand innovation and training in interventional cardiology

The Society for Cardiovascular Angiography & Interventions (SCAI) and Cardiovascular Research Technologies (CRT) today announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives.

2 Dec 2025

Fragmented sleep worsens recovery outcomes after traumatic brain injury

A new study highlights how important uninterrupted sleep is to recovery after a traumatic brain injury, finding that fragmented sleep in injured mice is linked to a loss of rapid-eye-movement (REM) sleep and increased fatigue.

2 Dec 2025

Protein tied to ALS and dementia plays a role in regulating DNA mismatch repair

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process essential for replicating genetic information and cell health.

2 Dec 2025

Cocktail of three supplements improves social behaviors in autistic mice

Researchers led by Tzyy-Nan Huang and Ming-Hui Lin from Academia Sinica in Taiwan report that a low-dose mixture of zinc, serine, and branch-chain amino acids can alleviate behavioral deficits in three different mouse models of autism.

2 Dec 2025

New study reveals how brain biology shapes thought and behavior

A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain's smallest components build the systems that shape thought, emotion and behavior.

2 Dec 2025

Lack of dietary iron weakens immune response in the lungs

Researchers at Columbia University have found that a lack of dietary iron early in life can prevent immune cells in the lung from making a key protein that helps fight viral infections, even after iron levels are restored.

2 Dec 2025

Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in post-menopausal women with obesity.

2 Dec 2025

Cell nucleus shape plays a key role in cancer therapy outcomes

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden.

2 Dec 2025

How tick saliva reprograms the skin’s immune defenses

A research team led by the Medical University of Vienna has gained new insights into how ticks influence the human immune system in order to introduce pathogens.

2 Dec 2025

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Alzheimer's disease blood biomarkers increase up to 95% faster in obese individuals

Researchers have conducted the first study evaluating the impact of obesity on Alzheimer's disease blood biomarkers (BBMs).

2 Dec 2025

Specific DNA sequences control spinal cord injury response

After a spinal cord injury, cells in the brain and spinal cord change to cope with stress and repair tissue. A new study from Karolinska Institutet, published in Nature Neuroscience, shows that this response is controlled by specific DNA sequences.

2 Dec 2025