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Targeting telomere damage offers new path to boost cancer immunotherapy

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

10 Sep 2025

New method reveals how mitochondrial DNA mutations influence cancer growth

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might affect cancer growth.

10 Sep 2025

GABA identified as key blocker of neural repair in spinal cord injury

Spinal cord injuries caused by external trauma, such as traffic accidents or falls, often lead to the permanent loss of motor and sensory functions.

10 Sep 2025

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Researchers found that THC, the psychoactive compound in cannabis, alters oocyte gene expression, spindle formation, and chromosome segregation, lowering embryo euploidy rates in IVF. This provides direct human evidence linking cannabis exposure to impaired female fertility outcomes.

10 Sep 2025

Daylight saving time does not increase heart attack risk, study shows

A large U.S. registry study of more than 168,000 patients found that daylight saving time (DST) clock changes did not increase heart attack rates or worsen in-hospital outcomes. The findings suggest that the lost or gained hour is unlikely to trigger acute myocardial infarction in contemporary care.

10 Sep 2025

Lung tumors rewire immune cells in the bone marrow before they reach cancer sites

Lung tumors don't just evade the immune system. They reshape it at its source. Researchers from the Icahn School of Medicine at Mount Sinai and collaborators report in the September 10 online issue of Nature that tumors rewire immune cells in the bone marrow before they even reach the cancer, suggesting a new target to enhance the durability of current immunotherapy

10 Sep 2025

Key proteins found to shape sperm function and male fertility

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant.

10 Sep 2025

Nanobody-based strategy targets survivin to weaken cancer cells

Cancer cells have many strategies for resisting therapy. One such strategy is survivin, a protein that drives the division of diseased cells and prevents them from dying.

10 Sep 2025

Long-read sequencing uncovers massive DNA elements shaping human oral microbiome

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection.

10 Sep 2025

Microbial piracy offers clues to fighting antimicrobial resistance

Researchers have discovered how 'pirate phages' hijack other viruses to break into bacteria, sharing new genetic material for dangerous traits.

10 Sep 2025

Precision nutrition offers new pathways to slow biological aging

Diet doesn't just fuel the body, it sends molecular signals that can slow down or speed up biological aging, according to a new perspective in npj Aging (Nature Portfolio).

10 Sep 2025

Detecting causality in neural spike trains using a new technique

Understanding the brain's functional architecture is a fundamental challenge in neuroscience. The connections between neurons ultimately dictate how information is processed, transmitted, stored, and retrieved, thus forming the basis of our cognitive functions.

10 Sep 2025

New AI model can identify treatments that reverse disease states in cells

In a move that could reshape drug discovery, researchers at Harvard Medical School have designed an artificial intelligence model capable of identifying treatments that reverse disease states in cells.

10 Sep 2025

New technique used to conduct real-time measurement of boron in live tumor cells

A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumors in some cancers.

10 Sep 2025

Rapid neuronal evolution linked to high prevalence of autism in humans

A new paper in Molecular Biology and Evolution, published by Oxford University Press, finds that the relatively high rate of Autism-spectrum disorders in humans is likely due to how humans evolved in the past.

10 Sep 2025

Bee-sting inspired microneedle patches offer pain-free drug delivery

Neurological diseases affect millions worldwide, and the need for long-term patient-friendly treatments has never been greater.

10 Sep 2025

Study uncovers new associations between gut microbiome and aging process

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 1, 2025, titled "Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels."

10 Sep 2025

Johns Hopkins team develops urine-based test for prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

9 Sep 2025

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025