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Study uncovers new mechanism for chromosome congression during mitosis

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division. The study demonstrates that two motor proteins, KIF18A and CENP-E, act cooperatively to ensure proper chromosome congression. Remarkably, simultaneous inhibition of these proteins selectively kills cancer cells, suggesting a promising therapeutic avenue.

10 Nov 2025

Comparative study finds higher rates of adverse events with ticagrelor

One year of treatment with either of two strong blood-thinning medications—ticagrelor and prasugrel—by people with type 1 or type 2 diabetes who had a drug-eluting stent placed in their heart to treat coronary artery blockages did not offer the same level of benefit to prevent stent clotting, heart attacks, and bleeding complications, according to findings presented during a preliminary late-breaking science session during the American Heart Association's Scientific Sessions 2025 in New Orleans on November 10.

10 Nov 2025

Green-synthesized nanoparticles enhance cidofovir's anticancer efficacy

In this study, led by Nahid Shahabadi from Razi University in Kermanshah, researchers developed an environmentally friendly approach to enhance the performance of cidofovir, a drug used to treat infections caused by DNA viruses. The work responds to the growing need for therapies that are safer, more effective, and better targeted.

10 Nov 2025

Scientists pinpoint a reason Alzheimer’s patients forget loved ones

One of the most devastating moments for family members of a patient with Alzheimer's is when their loved one forgets who they are. New University of Virginia School of Medicine research may explain why that happens and could lead to a way to prevent it.

10 Nov 2025

Micro-RNA in sperm proves vital for human embryogenesis

The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University, Sweden, shows that certain molecules that come with the sperm, so-called micro-RNA, contribute to the development of the embryo several days after conception. The findings, published in the journal Nature Communications, may in the long term contribute to better diagnosis and treatment of involuntary childlessness.

10 Nov 2025

Blood protein pattern linked to increased risk of hereditary atherosclerosis

A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is shown in a new study from Karolinska Institutet, examining close relatives of people who had suffered a heart attack at a young age.

10 Nov 2025

Babies show stronger brain response to their mothers’ voices

In a new JNeurosci paper, Sarah Jessen and colleagues, from the University of Lübeck, explored how infants track their mothers' voices compared to unfamiliar voices.

10 Nov 2025

Understanding communication complexity among infants with neurogenetic syndromes

Nancy Brady has been gratified to see the tool she and colleagues pioneered over a decade ago to measure the growth of infants' pre-speech communication skills translated into several languages and referenced in more than 100 research papers, including a åçnew one published in the Journal of Speech, Language and Hearing Research.

10 Nov 2025

Study finds reduced cortical choline levels in people with anxiety disorders

People with anxiety disorders have lower levels of choline in their brains, according to research from UC Davis Health.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Study identifies thyroid hormone pathway as key player in prostate cancer development

A hormone produced in the thyroid gland can play a key role in the development of prostate cancer.

10 Nov 2025

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Scientists have uncovered a surprising connection between sugar metabolism and alcohol addiction, identifying a potential new therapeutic target for treating alcohol-associated liver disease (ALD) and alcohol use disorder (AUD).

10 Nov 2025

Groundbreaking vaccination approach could transform respiratory disease prevention

A research team from Trinity College Dublin has unveiled a groundbreaking new approach to vaccination that could redefine how we protect against respiratory infections.

10 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Can your gut bacteria predict your age and lifestyle? New study says yes

Researchers used a new covariance-based method, MANOCCA, to map how environmental factors like age, sex, smoking, and BMI shape bacterial co-abundance in the healthy gut microbiome. The study revealed that key microbial interactions cluster in a few core families and that MANOCCA predicts host traits more accurately than standard models.

9 Nov 2025

How modern habits are reshaping the Mediterranean diet for the worse

Nearly all children and adolescents in five Mediterranean countries consume unhealthy ultra-processed foods daily, according to the DELICIOUS Project. The study links higher intake to obesity, older age, screen time, eating out, and exposure to food advertising.

9 Nov 2025

Why talking to yourself in third person can help you feel better before big moments

Researchers studying over 20,000 daily experiences found that people mostly talk to themselves in the first person, while using third-person, distanced self-talk far less often. Yet when they do, this detached inner voice offers a small but real emotional boost, especially when preparing for upcoming actions or performances.

9 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Using estimated risks and preferences to justify intensive BP control in CKD patients

An analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) indicates that nearly all adults with chronic kidney disease (CKD) would have benefits that outweigh the harm from a systolic blood pressure target of <120 mm Hg compared with a target of <140 mm Hg. The findings will be presented at ASN Kidney Week 2025 November 5– 9.

8 Nov 2025

Preclinical evidence supports sotagliflozin's superior efficacy in attenuating salt-induced kidney damage

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, initially developed to treat type 2 diabetes, have significant heart- and kidney- protective effects. In the kidney, SGLT2 reabsorbs approximately 97% offiltered glucose in the S1 and S2 segments of the proximal tubule, while SGLT1reabsorbs the remainder in the S3 segment.

8 Nov 2025

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Medical Science News

Study uncovers new mechanism for chromosome congression during mitosis

Comparative study finds higher rates of adverse events with ticagrelor

Green-synthesized nanoparticles enhance cidofovir's anticancer efficacy

Scientists pinpoint a reason Alzheimer’s patients forget loved ones

Micro-RNA in sperm proves vital for human embryogenesis

Blood protein pattern linked to increased risk of hereditary atherosclerosis

Babies show stronger brain response to their mothers’ voices

Understanding communication complexity among infants with neurogenetic syndromes

Study finds reduced cortical choline levels in people with anxiety disorders

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Study identifies thyroid hormone pathway as key player in prostate cancer development

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Groundbreaking vaccination approach could transform respiratory disease prevention

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Can your gut bacteria predict your age and lifestyle? New study says yes

How modern habits are reshaping the Mediterranean diet for the worse

Why talking to yourself in third person can help you feel better before big moments

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Using estimated risks and preferences to justify intensive BP control in CKD patients

Preclinical evidence supports sotagliflozin's superior efficacy in attenuating salt-induced kidney damage

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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