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Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Terasaki Institute and Caltech join forces on groundbreaking embryo formation study

The Terasaki Institute for Biomedical Innovation (TIBI) is pleased to announce its collaboration with the California Institute of Technology (Caltech) on a newly awarded $2.8 million Discovery Stage Research (DISC0) grant from the California Institute for Regenerative Medicine (CIRM).

14 Nov 2025

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025

New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.

14 Nov 2025

Enhancing the cancer-immunity cycle through innovative vaccines

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat malignancies.

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Indero announces breakthrough method for early-phase evaluation of topical drugs using quantitative gene expression

Indero is proud to announce the successful completion of an internally funded study that introduces a novel approach to evaluating topical new chemical entities (NCE) in early-phase clinical research.

14 Nov 2025

VR raises eye temperature and thickens protective tear layer

VR gaming impacts tear film dynamics, increasing lipid layer thickness and eye temperature, but fails to enhance tear stability or alleviate dry eye symptoms.

14 Nov 2025

Magnetic microrobots guide drugs directly to blood clots

Every year, 12 million people worldwide suffer a stroke; many die or are permanently impaired. Currently, drugs are administered to dissolve the thrombus that blocks the blood vessel.

14 Nov 2025

UCSF study explores sentiment analysis for hepatorenal syndrome

Taking a page from market research tactics, UC San Francisco experts are studying whether artificial intelligence (AI) can improve diagnosis of a complex liver condition by using the clinical notes of multiple providers.

14 Nov 2025

Cardiologists recommend reassessing need for additional stents later

A blocked coronary artery causing an acute heart attack must be opened immediately with a stent procedure. However, if other coronary arteries also appear to be narrowed, it is safe to wait and treat those later. This approach cuts the number of stent procedures in half, according to cardiologists from Radboud university medical center, writing in The New England Journal of Medicine.

14 Nov 2025

Study unites global neuroscientists to share brain data

Imagine if every neuroscientist in the world could suddenly speak the same language and share their discoveries instantly. Allen Institute researchers and engineers have now unlocked that potential and the vast discoveries it could lead to through the new Brain Knowledge Platform (BKP).

14 Nov 2025

Bringing accessible NGS-based proteomics to even more labs

At Olink, our mission has always been clear: to make high-quality proteomics accessible to every lab.

From Olink®- Part of Thermo Fisher Scientific 13 Nov 2025

High protein breakfasts help you feel fuller but do not change how much you eat later

High protein breakfasts, whether plant or animal-based, boosted GLP-1 and PYY and modestly reduced appetite compared with a low protein, high carbohydrate meal. Despite these hormonal and appetite changes, lunchtime energy intake remained unchanged in both younger and older adults.

13 Nov 2025

New study reveals how the uterus senses force to drive labor

When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely.

13 Nov 2025

Tiny antibiotic traces found to greatly accelerate resistance spread

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

13 Nov 2025

Scientists reveal how prolonged UV exposure weakens cellular defense against skin cancer

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can significantly increase the risk of skin cancer.

13 Nov 2025

Scientists map the genetic control system behind FOXP3 in immune cells

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

13 Nov 2025

New approach revives DNA from historic medical tissues

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

13 Nov 2025

Modular magnetic microrobots achieve precision drug delivery

A magnetically guided microrobotics system is capable of navigating the body's intricate passageways and vasculature to deliver drugs with pinpoint accuracy, according to a new study.

13 Nov 2025