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New analysis identifies safer treatment paths for children with medulloblastoma

By analyzing data from three clinical trials treating children with the brain tumor medulloblastoma, scientists at St. Jude Children's Research Hospital have designed an approach to safely reduce therapy, thereby lowering side effects.

5 Nov 2025

What’s driving England’s rise in chronic illness? Ageing, not lifestyle, researchers find

A new Nature Communications study using the IMPACTNCD microsimulation model projects that England’s major illness burden will rise sharply by 2043, even with substantial lifestyle improvements. Population ageing, not modifiable risk factors, remains the dominant driver of future multimorbidity.

5 Nov 2025

MIT researchers identify new vaccine targets to fight tuberculosis

A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world's deadliest infectious disease.

5 Nov 2025

Aggression and self-harm could share a common neural basis

Aggression and self-harm often co-occur in individuals with a history of early-life trauma-a connection that has largely been documented by self-reporting in research and clinical settings.

5 Nov 2025

Galectin-3 found to drive crucial cell fusion in early placental development

During the first weeks of pregnancy, the developing placenta in a mother's womb undergoes a dramatic change.

5 Nov 2025

How gut microbes shape sleep: New review reveals microbiome clues to insomnia and apnea

A new Brain Medicine review maps how gut microbes influence sleep disorders, from insomnia and sleep apnea to circadian disruption, via bile acids, neurotransmitters, and immune pathways. The findings highlight gut-driven targets for improving sleep quality through diet, probiotics, and microbiome modulation.

5 Nov 2025

New AI-assisted atlas can help visualize the human brain in unprecedented detail

A new AI-assisted brain atlas that can help visualize the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging.

5 Nov 2025

Inhibiting ferroptosis suppressor protein 1 shrinks lung cancers in mice

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

5 Nov 2025

Opioid receptors caught in motion offering clues for safer painkillers

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was exactly what happens next.

5 Nov 2025

EULAR develops first classification criteria for hemochromatosis arthropathy

EULAR - The European Alliance of Associations for Rheumatology - has developed the first classification criteria for hemochromatosis arthropathy (HA) from a unique derivation cohort using rigorous methodology.

5 Nov 2025

Do gut microbes cause autism? New research says diet plays the bigger role

In a family-based study, researchers found that children with autism spectrum disorder (ASD) shared similar gut microbiomes with their relatives but showed distinctly different eating habits. Their preference for sweets and limited vegetable intake suggests behavior-driven dietary choices may influence, rather than result from, microbiome differences.

5 Nov 2025

Researchers uncover molecular key to prevent brown fat decline with age

As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and certain chronic cardiovascular diseases that worsen with age.

5 Nov 2025

Nerve injuries found to affect the entire immune system in unexpected ways

Nerve injuries can have long-lasting effects on the immune system that appear to differ between males and females, according to preclinical research from McGill University.

5 Nov 2025

Breakthrough study reveals how rabies virus uses few proteins to hijack cells

New antivirals and vaccines could follow the discovery by Australian researchers of strategies used by viruses to control our cells.

5 Nov 2025

$Adipose tissue stem cells show promise in treating osteoporotic vertebral fractures$

Adipose tissue stem cells show promise in treating osteoporotic vertebral fractures

An Osaka Metropolitan University team has used stem cells extracted from adipose, the body's fatty tissue, to treat spine fractures in rats similar to those caused by osteoporosis in humans.

5 Nov 2025

Gut bacteria metabolize nitrogen compounds to prevent cancer-causing nitrosamines

Nitrogen metabolism of gut bacteria can provide health benefits. Specifically, gut microbes metabolize dietary nitrates and nitrites and prevent the formation of cancer-causing compounds called nitrosamines.

5 Nov 2025

PTGES3 emerges as key regulator of androgen receptor in prostate cancer

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate cancer.

5 Nov 2025

Super recognizers excel by looking smarter not harder

What is it that makes a super recognizer – someone with extraordinary face recognition abilities – better at remembering faces than the rest of us?

4 Nov 2025

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed an innovative strategy to construct a series of biodegradable cesium nanosalts.

4 Nov 2025