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NJHF awards $135K to Kessler Foundation scientists for pilot research projects

This year, New Jersey Health Foundation (NJHF) granted $135,000 in awards to three Kessler Foundation scientists to support pilot research projects that exhibit promising potential.

13 Apr 2024

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

13 Apr 2024

Cas13d-NCS: A game-changer in RNA virus defense

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate.

13 Apr 2024

Genetic predisposition for muscle strength linked to longer lifespan and lower disease risk

A study conducted at the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower risk for developing common diseases.

13 Apr 2024

Study shows exercise can reverse age-related lipid accumulation

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.

13 Apr 2024

Soft tumor environments prime cancer cells for survival during metastasis

Researchers have discovered how the mechanical properties of tumors can prime cancer cells to better survive their spread to other organs.

13 Apr 2024

Study finds dysfunction of key brain systems in people with psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.

13 Apr 2024

Wearable devices reveal stress-related changes during sleep

What if changes in a person's stress levels could be detected while they sleep using wearable devices? A new study by University of Vermont researchers published today in PLOS Digital Health is the first to find changes in perceived stress levels reflected in sleep data-;an important step towards identifying biomarkers that may help flag individuals in need of support.

13 Apr 2024

Neural circuitry in the spinal cord allows brain-independent motor learning

Aya Takeoka at the RIKEN Center for Brain Science (CBS) in Japan and colleagues have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning.

13 Apr 2024

Study reveals metabolic markers linked to long COVID-19 severity

Long COVID-19, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a global health phenomenon characterized by persistent symptoms following the acute phase of COVID-19.

13 Apr 2024

New murine model sheds light on anti-MDA5 antibody-positive dermatomyositis

Some diseases involve autoimmune reactions, when the body begins to attack its own cells and proteins.

13 Apr 2024

Research sheds light on post-sepsis immune suppression mechanism

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.

13 Apr 2024

New microfluidic device improves the separation of tumor cells and clusters from malignant effusions

Researchers have unveiled a microfluidic device that significantly improves the separation of tumor cells and clusters from malignant effusions.

13 Apr 2024

Unraveling the mysteries of gastro-esophageal junction development

The transition from the esophagus to the stomach is a delicate region from a medical point of view, often associated with pathological disorders leading to cancer.

13 Apr 2024

ERC Advanced grant awarded to crack the code of cartilage repair

In our aging society, healing joint problems is becoming increasingly important. To do this, cartilage damage must become repairable.

12 Apr 2024

Study aims to explore the underlying causes of excessive alcohol production in overweight people

The microorganisms in the intestines of many overweight people produce alcohol to an increased extent, as Max Nieuwdorp, professor of Internal Medicine at Amsterdam UMC discovered a few years ago.

12 Apr 2024

Innovative cancer treatment approach yields promising results in pediatric patients

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples.

12 Apr 2024