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Multidimensional regulation of stem cell fate by the cohesin complex

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.

10 Oct 2025

Study reveals how DKK3 triggers smooth muscle cell transformation in aortic aneurysm

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder that primarily affects elderly males.

10 Oct 2025

Advances in nanomaterials revolutionize therapy for myocardial ischemia-reperfusion injury

Ischemic heart disease is the leading cause of death globally, causing approximately 9 million deaths annually.

10 Oct 2025

Researchers identify key role of lactylation in driving aortic dissection

Recently, a research team led by Professor Jian-Xun Wang and Professor Tao Yu from Qingdao University made a significant breakthrough in understanding the role of lactylation modification in aortic dissection (AD).

10 Oct 2025

A blood test breakthrough for detecting heart damage from cancer therapy

Treatments for cancer are continuously improving, but they can still cause debilitating, even fatal, side effects.

10 Oct 2025

Cyclic peptide nanotubes offer new route to overcome cancer drug resistance

A research team at CiQUS (University of Santiago de Compostela, Spain) has unveiled an innovative molecular approach that enables anticancer drugs to reach the nucleus of tumor cells, where they can exert their therapeutic effect.

10 Oct 2025

Discovery of unique brain cells sheds light on progressive multiple sclerosis

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.

10 Oct 2025

How much caffeine is safe during pregnancy? New review finds no clear threshold

Caffeine's impact on pregnancy is nuanced; moderate consumption may not lead to major complications, but risks to fetal growth persist without a safe threshold.

10 Oct 2025

Can too much exercise strain the heart?

The concept of ‘heartbeat consumption’ is introduced as a valuable metric that provides insights into the possible adverse effects of intense exercise.

10 Oct 2025

Personalized chatbot feedback encourages teens to drink less sugar

Researchers investigate how teenagers respond to a personalized chatbot intervention designed to reduce their sugar intake.

10 Oct 2025

Harvard researchers augment LLM to create expert diagnostic system

Except for one key aspect, the setup is a familiar one in medicine: An expert diagnostician presents a particularly challenging case to a roomful of colleagues, carefully walking them through the patient's symptoms and initial test results.

10 Oct 2025

UCLA scientists uncover the role of DGRs in structuring the infant gut microbiome

Everywhere you go, you carry a population of microbes in your gastrointestinal tract that outnumber the human cells making up your body.

10 Oct 2025

Study reveals acidic conditions as key to pancreatic cancer survival

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

9 Oct 2025

Deep brain stimulation shows promise in reducing severe stuttering

While stuttering was believed to have purely psychological causes up until about 30 years ago, scientists today attribute it to a variety of factors capable of contributing to its development.

9 Oct 2025

Researchers develop AI system to decode the human immune system

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved.

9 Oct 2025

New gene therapy reverses symptoms of SYNGAP1-related disorders in mice

In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice.

9 Oct 2025

Women show peak cognitive performance during ovulation but exercise matters more

Women performed best on cognitive tests during ovulation but physical activity level had a stronger influence on brain function, according to a new study from researchers at UCL.

9 Oct 2025

New blood atlas reveals how diseases leave unique protein signatures

A new study has mapped the distinct molecular "fingerprints" that 59 diseases leave in an individual's blood protein – which would enable blood tests to discern troubling signs from those that are more common.

9 Oct 2025

Portable sensor can accurately detect synthetic cannabinoids in e-cigarette and biological samples

Even though electronic cigarettes do not contain any illicit substances, the liquid can cause serious health problems.

9 Oct 2025

Using a lab-designed protein to regulate blood glucose levels

Researchers at the Indiana University School of Medicine have discovered a new way to regulate blood glucose levels using a lab-designed protein, possibly opening the door to a new treatment avenue for people with Type 1 diabetes.

9 Oct 2025