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Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Misha Kudryshev's lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia.

4 Sep 2024

Magnetic nanoparticles enhance safe thawing of cryopreserved tissues

Every day, people die waiting for an organ transplant. Time is at a premium, not just for those awaiting organs, but also for the organs themselves, which can deteriorate rapidly during transportation.

4 Sep 2024

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

Today, the Allen Institute for Cell Science and New York Stem Cell Foundation (NYSCF) announced a pioneering collaboration to address this critical issue, combining two cutting-edge technologies to create more inclusive cellular models for studying disease.

4 Sep 2024

New immunotherapy approach shows promise for minimizing spinal cord injury damage

WashU Medicine researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells.

4 Sep 2024

Sports concussions may not be related to long-term cognitive risks for non-professional athletes

Sports-related concussions (SRC) may not be associated with long-term cognitive risks for non-professional athletes, a study led by a UNSW medical researcher suggests.

4 Sep 2024

Lifestyle interventions in patients after colorectal cancer treatment

A recent RCT reveals the HEAL ABC intervention is feasible for 87% of colorectal cancer survivors, supporting healthy lifestyle changes and improved well-being.

4 Sep 2024

Avadel Pharmaceuticals announces publication of RESTORE data highlighting challenges with twice-nightly oxybates and strong patient preference for once-nightly LUMRYZ™ dosing (sodium oxybate) extended-release oral suspension (CIII)

Avadel Pharmaceuticals plc, a biopharmaceutical company focused on transforming medicines to transform lives, today announced the publication of final data from the RESTORE open-label/switch study, demonstrating that people with narcolepsy prefer once-at-bedtime LUMRYZ versus a twice-nightly immediate-release oxybate treatment option.

From Avadel Pharmaceuticals 4 Sep 2024

Understanding the impact of BMI on colorectal cancer risk in Asia

Researchers report that body mass index values in Asians population may predict the risk of developing colorectal cancer.

4 Sep 2024

Does air pollution drive dementia?

Chronic air pollution exposure is a key factor in dementia development, with pollutants like PM2.5 and NO2 linked to cognitive decline and neurodegeneration.

4 Sep 2024

Sleep too much or too little? Your cognition pays the price

Findings indicate that both insufficient and excessive sleep are linked to higher mild cognitive impairment risk, underscoring the importance of balanced sleep.

4 Sep 2024

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Researchers reveal how aging and psychiatric disorders converge at the cellular level in the orbitofrontal cortex, identifying key gene expression changes that could lead to new therapies.

4 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

Ultra-processed foods significantly raise heart disease risk

Higher intake of ultra-processed foods is linked to increased risks of coronary heart disease and cardiovascular disease in U.S. adults, with certain processed foods like meats and sugary drinks posing significant dangers.

4 Sep 2024

Study shows how troriluzole can target early-stage alterations associated with Alzheimer's

In a recent development in Alzheimer's disease research, Auburn University scientists have studied a new drug, troriluzole, that can prevent brain changes leading to memory loss and cognitive decline in a mouse model of the disease.

3 Sep 2024

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.

3 Sep 2024

Discovery of cellular process could impact the understanding of cancer and aging

Researchers at UC Merced used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging.

3 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

Gut bacteria pathways directly linked to insomnia risk identified

Study uncovers a causal link between specific gut microbiome metabolic pathways and insomnia, highlighting potential therapeutic targets for improving sleep quality.

3 Sep 2024

New computational tool accurately assesses health through gut microbiome analysis

A team of Mayo Clinic researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms within the digestive system, to provide insights into overall well-being.

3 Sep 2024

Metabolic syndrome risk: The role of diet in young adults

Researchers found that young adults following a Legume-Nut diet with irregular physical activity have a higher risk of metabolic syndrome, while those on an Egg-Vegetable diet face a lower risk. Regular physical activity significantly modifies these risks.

3 Sep 2024

Medical Science News

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Magnetic nanoparticles enhance safe thawing of cryopreserved tissues

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

New immunotherapy approach shows promise for minimizing spinal cord injury damage

Sports concussions may not be related to long-term cognitive risks for non-professional athletes

Lifestyle interventions in patients after colorectal cancer treatment

Avadel Pharmaceuticals announces publication of RESTORE data highlighting challenges with twice-nightly oxybates and strong patient preference for once-nightly LUMRYZ™ dosing (sodium oxybate) extended-release oral suspension (CIII)

Understanding the impact of BMI on colorectal cancer risk in Asia

Does air pollution drive dementia?

Sleep too much or too little? Your cognition pays the price

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

A novel therapeutic option for HER2-positive extramammary Paget disease

Ultra-processed foods significantly raise heart disease risk

Study shows how troriluzole can target early-stage alterations associated with Alzheimer's

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

Discovery of cellular process could impact the understanding of cancer and aging

PQBP3 protein found to play key role in aging and brain disorders

Gut bacteria pathways directly linked to insomnia risk identified

New computational tool accurately assesses health through gut microbiome analysis

Metabolic syndrome risk: The role of diet in young adults

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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