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New kidney tissue atlas could advance understanding of kidney injury and disease

Researchers at Washington University School of Medicine in St. Louis helped lead a major study, funded by the National Institutes of Health (NIH), that uncovered rich cellular and molecular diversity in healthy and diseased kidneys, creating a kidney tissue atlas that will help further understanding of kidney injury and disease.

19 Jul 2023

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

The discovery of antibiotics in 1928 was a major turning point in the history of medicine. For the first time since the dawn of human civilization, doctors had gained access to an extremely powerful and effective tool to fight against a wide variety of bacterial infections.

19 Jul 2023

Cardiac rehabilitation linked to decreased risk of death after surgery

For millions of Americans who have heart surgery or experience cardiovascular complications, like heart attack or heart failure, they may be encouraged to participate in cardiac rehabilitation.

19 Jul 2023

Older adults see the benefit in cognitive screening, but many have not been tested

Eighty percent of older adults see the benefit of tests that can give an early warning that a person's memory and thinking abilities have started to decline, a new poll of people age 65 to 80 finds.

19 Jul 2023

Research opens new possibilities for treating inflammatory diseases

The inflammatory response is indispensable for protective immunity, yet microbial pathogens often trigger an excessive response, 'cytokine storm', harmful to the host.

19 Jul 2023

The painful legacy of ‘law and order’ treatment of addiction in jail

Megan Dunn, who has struggled with addiction since her teens, points to the moment her life went "deeply downhill."

19 Jul 2023

How diet, exercise can improve mental and physical functioning in older cancer survivors

Researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and Dana Farber Cancer Institute in Boston have been awarded $7 million in total funding to study how diet and exercise impact mental and physical functioning in older cancer survivors and their caregivers.

18 Jul 2023

Opioid addiction linked to neural differences in response to drug cues

An Icahn School of Medicine at Mount Sinai study sheds new light on some of the underlying neurobiological mechanisms of opioid addiction, which accounted for three-quarters of the more than 100,000 fatal drug overdoses in the United States in 2021.

18 Jul 2023

Study reveals molecular mechanisms of H. pylori-induced gastric carcinogenesis

Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA+ strains dramatically increases the risk of developing gastric cancer.

18 Jul 2023

EAE Hub model reduces barriers to early autism diagnosis

A new study led by Indiana University School of Medicine researchers shows primary care clinicians who receive specialized training can make accurate autism diagnoses for over 80 percent of young children referred with developmental delays, providing compelling evidence that community-based models of autism evaluation are a potential solution for improving access to this needed service.

18 Jul 2023

Hearing aids may offer protection against cognitive decline in older adults at high risk of dementia

While hearing aids and audiological support services did not have any impact on cognitive decline over 3 years in a general population of older adults, treating hearing loss protected against cognitive decline in older adults at greater risk of dementia.

18 Jul 2023

MCW professor awarded $13 million NIH grant to study misplaced calcification in AMD and Alzheimer's

Francesca Marassi, PhD, professor and chair of biophysics at the Medical College of Wisconsin (MCW), has been awarded a five-year, $13 million program project grant (PPG) by the National Institutes of Health (NIH) to study misplaced calcification in the eyes and brains of patients suffering from age-related macular degeneration (AMD) and Alzheimer's disease (AD).

18 Jul 2023

Study finds link between DHX9 gene mutations and neurodevelopmental disorders

A group of 20 patients with undiagnosed neurodevelopmental disorders ranging from severe to mild has now received a genetic diagnosis thanks to an international team of researchers at the GREGoR Research Center at Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions.

18 Jul 2023

CEPI and HMRI partner to accelerate development of pandemic vaccines

CEPI, the Coalition for Epidemic Preparedness Innovations, and the Houston Methodist Research Institute (HMRI), have today announced a partnership to combine cutting-edge artificial intelligence (AI) technology with established laboratory techniques to speed up development of future vaccines against novel viral threats (also known as Disease X).

18 Jul 2023

Rice bioengineers receive NIH grant for sickle cell disease research

Rice University bioengineer Gang Bao and his team have won a 4-year, $2.6 million grant from the National Institutes of Health to address critical questions surrounding the safety and efficacy of using gene editing to treat sickle cell disease.

18 Jul 2023

Targeted brain stimulation shows promise for treating TBI-related memory loss

Traumatic brain injury (TBI) has disabled 1 to 2% of the population, and one of their most common disabilities is problems with short-term memory. Electrical stimulation has emerged as a viable tool to improve brain function in people with other neurological disorders.

18 Jul 2023

Vanderbilt receives $7 million grant to study sedatives for critically ill patients

Vanderbilt University Medical Center has received a $7 million, five-year funding award from PCORI (Patient-Centered Outcomes Research Institute) to compare two sedatives used to place breathing tubes in the emergency department (ED) or intensive care unit (ICU).

18 Jul 2023

Spinal fluid test could be used for early detection of Lewy body disease

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test.

18 Jul 2023

Breast milk antibodies vary widely among mothers

Breast milk from each individual contains a unique assemblage of antibodies that are surprisingly stable throughout lactation and across pregnancies, according to a new Journal of Experimental Medicine study from the University of Pittsburgh School of Medicine.

18 Jul 2023

Allen Institute and Lilly collaborate to develop new treatments for immune-mediated diseases

In a significant milestone for the Allen Institute for Immunology, a division of the Allen Institute, researchers and staff will collaborate with private industry researchers to aid in the detailed molecular understanding of disease, in service of developing new treatments and therapies to improve human health.

18 Jul 2023