Tumor News and Research

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CINJ clinical trial explores anti-malaria drug against melanoma

Building upon recent laboratory discoveries on resistance by cancer cells to therapies that attempt to starve cancer, scientists at The Cancer Institute of New Jersey (CINJ) are conducting a clinical trial that further explores how to prevent that action.

14 Jan 2011

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Massachusetts General Hospital Cancer Center researchers have discovered a previously unknown feature of common tumor cells - massive overexpression of certain DNA sequences that do not code for proteins.

14 Jan 2011

Scientists demonstrate mechanism that explains why PSA levels promote prostate cancer

Researchers at the Duke Cancer Institute who have been studying prostate cancer cells for decades now think they know why PSA levels reflect cancer progression.

14 Jan 2011

Study highlights role of SIRT1 protein as tumor suppressor in prostate cancer

Researchers from the Kimmel Cancer Center at Jefferson and two other institutions have discovered new evidence that suggests the "longevity" protein SIRT1, known for its life-spanning effects in different species, can inhibit the development of a known precursor to prostate cancer, prostatic intraepithelial neoplasia.

14 Jan 2011

T.A. Sciences receives US patent for TA-65 to tackle aging process

Telomerase Activation Sciences, today announced the issuance of U.S. Patent No. 7,846,904 to the Geron Corporation. The patent covers the use of certain compounds to upregulate telomerase expression in cells.

14 Jan 2011

New research shows enzyme-armed oncolytic virus may help fight brain tumors

New research shows that oncolytic viruses, which are engineered to destroy cancer cells, might be more effective in treating deadly brain tumors if equipped with an enzyme that helps them penetrate the tumor.

13 Jan 2011

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Genomic research could help doctors better target a drug widely used to treat colorectal cancer patients, according to a study by Genomic Health Inc. and the Translational Genomics Research Institute.

13 Jan 2011

Philadelphia CTCA hospital purchases BSD-2000 Hyperthermia System

BSD Medical Corporation announced today that the Cancer Treatment Centers of America (CTCA) hospital at Eastern Regional Medical Center, located in Philadelphia, Pennsylvania, has purchased a BSD-2000 Hyperthermia System (BSD-2000). CTCA in Philadelphia is a state-of-the-art hospital that provides advanced cancer treatments, world-class technologies, and supportive therapies under one roof.

13 Jan 2011

Preoperative Breast MRI accurately detects otherwise occult cancer

The use of preoperative Breast MRI detects otherwise occult cancer with a relatively high degree of accuracy when applied to a diverse population of patients newly diagnosed with breast cancer, according to a study in the January issue of the American Journal of Roentgenology.

13 Jan 2011

TKM-PLK1 drug may offer hope for patients with advanced solid tumor cancers

A new investigational drug designed to stop cancer cells from reproducing may offer hope for patients with advanced solid tumor cancers. Clinical trials of TKM-PLK1 for qualified patients are now open at the Virginia G. Piper Cancer Center at Scottsdale Healthcare.

13 Jan 2011

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Beth Israel Deaconess Medical Center cancer geneticist Pier Paolo Pandolfi, MD, PhD, is the recipient of the 2011 Pezcoller Foundation-AACR (American Association of Cancer Research) International Award for Cancer Research.

13 Jan 2011

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

Pfizer Inc. announced today that it has initiated the rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for crizotinib (PF-02341066), an oral first-in-class anaplastic lymphoma kinase (ALK) inhibitor for the treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumors are ALK-positive. Pfizer expects to complete the submission in the first half of 2011.

13 Jan 2011

New discovery has brought dream of transforming measles virus against cancer

When most people in the developed world think of measles, what comes to mind is only a dim memory of a vaccination at a pediatrician's office. But while childhood vaccination has virtually eliminated measles from North America and much of Europe, researchers remain interested in the virus.

13 Jan 2011

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Some disorders of the brain are obvious - the massive death of brain cells after a stroke, the explosion in the growth of cells that marks a tumor. Other disorders, such as autism, schizophrenia and mental retardation show no physical signs of damage and are believed to be caused by problems in how brain cells communicate with one another.

13 Jan 2011

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

MedImmune, the global biologics unit of AstraZeneca PLC and Micromet, today announced the initiation of a Phase 1 trial of MEDI-565 in patients with advanced gastrointestinal cancers. MEDI-565 is a BiTE antibody designed to direct a patient's T cells, the body's most potent killer cells, against cancer cells that express carcinoembryonic antigen.

13 Jan 2011

Doctors matter in treatment of breast cancer

A recent journal article presents evidence that suggests that the course of treatment that a doctor chooses to treat a breast cancer patient may play a larger role in expected outcomes than was previously believed. The Journal of the National Cancer Institute's article (online 01/03/2011; print 01/19/2011) Breast Cancer Outcome: Your Doctor Matters examines variations in outcomes from surgeon to surgeon.

12 Jan 2011

Study shows delivering cancer drug in hydrophobic nanoparticle is a safe and effective prostate cancer therapy

Researchers at MIT and Brigham and Women's Hospital have shown that they can deliver the cancer drug cisplatin much more effectively and safely in a form that has been encapsulated in a nanoparticle targeted to prostate tumor cells and is activated once it reaches its target.

12 Jan 2011

Scientists find way to prevent early stage pancreatic cancer in research models

Cancer researchers at The Peggy and Charles Stephenson Oklahoma Cancer Center have found a way to stop early stage pancreatic cancer in research models - a result that has far-reaching implications in chemoprevention for high-risk patients.

12 Jan 2011

Epigenetic therapy holds promise for cancer management

Syndax, a clinical-stage epigenetics oncology company, announced publication of data of entinostat combined with the demethylating agent Vidaza® (azacitidine) showing effect in reducing tumor burden in differentiated tumor cells in animal tumor models of non-small cell lung cancer (NSCLC). The data is being published in the January 15, 2011 issue of Cancer Research.

12 Jan 2011

Illumina announces acquisition of Epicentre Biotechnologies

Illumina, today announced that it has acquired Epicentre Biotechnologies, a leading provider of nucleic acid sample preparation reagents and specialty enzymes used in sequencing and microarray applications.

From Illumina, Inc. 12 Jan 2011

Tumor News and Research

CINJ clinical trial explores anti-malaria drug against melanoma

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Scientists demonstrate mechanism that explains why PSA levels promote prostate cancer

Study highlights role of SIRT1 protein as tumor suppressor in prostate cancer

T.A. Sciences receives US patent for TA-65 to tackle aging process

New research shows enzyme-armed oncolytic virus may help fight brain tumors

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Philadelphia CTCA hospital purchases BSD-2000 Hyperthermia System

Preoperative Breast MRI accurately detects otherwise occult cancer

TKM-PLK1 drug may offer hope for patients with advanced solid tumor cancers

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

New discovery has brought dream of transforming measles virus against cancer

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

Doctors matter in treatment of breast cancer

Study shows delivering cancer drug in hydrophobic nanoparticle is a safe and effective prostate cancer therapy

Scientists find way to prevent early stage pancreatic cancer in research models

Epigenetic therapy holds promise for cancer management

Illumina announces acquisition of Epicentre Biotechnologies

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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