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New drug candidates may offer breakthrough in treatment of COPD

The study was a cooperative effort between the team headed by assistant professor Dr Jürgen Knobloch from the Medical Clinic III for Pneumology, Sleep and Respiratory Medicine at the Bergmannsheil University Hospital in Bochum, Germany, and Prof Dr Andrea Koch, member of the German Center for Lung Research, previously in Bochum, now at the Medical Clinic V for Pneumology at the LMU University Hospital in Munich, as well as a team from the company RespiVert Ltd, a subsidiary of Janssen Biotech Inc., and Prof Dr Erich Stoelben from the Lung Clinic in Köln-Merheim.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

Computer model based on AI improves analysis of kidney biopsies

The ability to quantify the extent of kidney damage and predict the life remaining in the kidney, using an image obtained at the time when a patient visits the hospital for a kidney biopsy, now is possible using a computer model based on artificial intelligence.

11 Jan 2018

CAP releases new guideline for HPV testing in patients with head and neck cancers

Certain head and neck cancers that are positive for high-risk types of human papillomavirus (HPV) have a better prognosis and may need less aggressive treatment.

11 Jan 2018

Elevated levels of inflammation marker linked to lower muscle mass

Elevated levels of the inflammation marker CRP in the blood is an underlying cause of the loss of muscle mass in elderly persons, as shown by a new study from örebro University and University of Nottingham.

11 Jan 2018

Implanted robotic system stimulates tissue growth in stunted organs

An implanted, programmable medical robot can gradually lengthen tubular organs by applying traction forces -- stimulating tissue growth in stunted organs without interfering with organ function or causing apparent discomfort, report researchers at Boston Children's Hospital.

11 Jan 2018

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Advanced glycation end products, which have been linked to many chronic diseases, including diabetes, cardiovascular disease and cancer, build up in the body from birth due to normal metabolism but are often higher in those eating the high-fat, high-sugar, highly processed foods characteristic of the Western diet.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Circadian rhythms could hold key to novel treatments for glioblastoma

Biological clocks throughout the body play a major role in human health and performance, from sleep and energy use to how food is metabolized and even stroke severity.

10 Jan 2018

Decorated cardiac stem cells could provide enhanced treatment for heart attacks

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury - and getting them to stay there - remains challenging.

10 Jan 2018

Physiological differences between Swedish and North American female ice hockey players

Female ice hockey players from North America have better financial conditions as well as greater leg strength and running acceleration than female ice hockey players from Sweden, who in return have less body fat.

10 Jan 2018

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems.

10 Jan 2018

Salk scientists identify molecular target of experimental Alzheimer’s drug

The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans.

10 Jan 2018

New 3-D imaging system offers insight into potential obesity and diabetes treatments

Researchers have developed A 3-D tissue imaging system that has revealed the inner workings of fat cells in mice, providing insight into potential therapeutic targets for combating obesity and diabetes.

10 Jan 2018

3D images of fat cells reveal potential targets to fight against obesity

Stunning three-dimensional images of fat cells, the first of their kind, are the latest tactic in the ongoing fight against the global obesity epidemic.

10 Jan 2018

General anesthesia may be more complex in its workings than we know now

Associate Professor Bruno van Swinderen from Queensland Brain Institute, University of Queensland with his colleagues have studied the workings of general anesthetics on the brain and found that these agents did more than just put a person to sleep. These findings could pave the way for better and more effective anesthetics they believe. The study was published in the latest issue of the journal Cell Reports.

10 Jan 2018

Scientists create artificial human muscles

Researchers have successfully created artificial human muscles in the laboratories that are tiny but fully functional. These small muscles actually respond to the nerve stimulations, says the latest study reporting this scientific breakthrough.

10 Jan 2018

Ibuprofen intake could be leading to male infertility

According a new study that appeared this week in the journal Proceedings of the National Academy of Sciences, simple pain reliever, Ibuprofen, could be having a problematic effect on the testes of young men. Ibuprofen is taken almost routinely by young athletes for injuries and pain.

9 Jan 2018