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IU researchers present groundbreaking findings at Alzheimer's conference

Researchers from Indiana University School of Medicine had a large presence and leadership role at the 2023 Alzheimer's Association International Conference in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

18 Jul 2023

Tight junctions between cells may play a critical role in gastrulation in human embryos

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo.

18 Jul 2023

Study finds gender bias in stroke treatment

Despite having worse stroke symptoms and living within comparable distances to comprehensive stroke centers, women with large vessel occlusion acute ischemic stroke are less likely to be routed to the centers compared to men, according to a new study from UTHealth Houston.

18 Jul 2023

Starting epidurals in the OR may help provide better pain control

Starting a patient-controlled epidural anesthesia (PCEA) infusion while the patient is still in the operating room (OR) - rather than in the recovery room after the procedure - may help provide better pain control, suggests research presented at the virtual American Society of Anesthesiologists' Anesthesia Quality and Patient Safety Meeting.

17 Jul 2023

Researchers find new genes that contribute to hypoplastic left heart syndrome

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants.

17 Jul 2023

Genes that influence pain perception linked to alcohol use disorders

An estimated 16 million people in the United States have alcohol use disorders (AUDs), according to the National Institutes on Alcohol Abuse and Alcoholism (NIAAA).

17 Jul 2023

Study establishes new link between genomic instability and bacterial protein in the urogenital tract

A team of researchers from the University of Maryland School of Maryland's (UMSOM) Institute of Human Virology (IHV), a Center of Excellence of the Global Virus Network (GVN), published new findings that emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development.

17 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

AI model accurately predicts which drugs may cause birth defects

Data scientists at the Icahn School of Medicine at Mount Sinai in New York and colleagues have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities.

17 Jul 2023

Study shines light on genetic differences among children with rare neurodevelopmental condition

New research led by the Seaver Autism Center for Research and Treatment at Mount Sinai has illuminated genetic differences among children with a rare neurodevelopmental condition and could point the way toward a precision medicine approach to caring for these children.

17 Jul 2023

Research shows redlining's long-term impact on cardiovascular health of Black adults

The risk of heart failure in the present day was higher among Black adults who lived in U.S. zip codes historically impacted by redlining, according to research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

17 Jul 2023

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

People with Down syndrome, the condition caused by an extra copy of chromosome 21, or trisomy 21, display chronic dysregulation of their immune system, which can contribute to high rates of autoimmune conditions and severe complications from respiratory infections.

17 Jul 2023

Merck awards 2023 Future Insight Prize for research into air sensor to detect pandemic pathogens

Merck KGaA, Darmstadt, Germany, awarded its 2023 Future Insight Prize to Khalid Salaita, professor of chemistry at Emory University. The award comes with $540,000 to fund the next phase of research into an air sensor that can continuously monitor indoor spaces for pathogens that can cause pandemics.

17 Jul 2023

Zebrafish study reveals how blood stem cells affect health

All humans have a diverse set of blood stem cell types which dictate the composition and function of our blood and immune cells and ultimately help govern overall health.

17 Jul 2023

Scent dogs may be a cheaper, faster and more effective way to detect COVID-19

Scent dogs may represent a cheaper, faster and more effective way to detect COVID-19, and could be a key tool in future pandemics, a new review of recent research suggests.

17 Jul 2023

PALACE study: Direct oral challenge can safely remove penicillin allergy label

Penicillin allergy affects more than 25 million people in the United States (up to 1 in 10 Americans) and has been shown to lead to particularly poor health outcomes in pregnant women and surgical patients. It is also a public health threat, leading to antibiotic resistance and infections in hospitalized patients that can be life threatening.

17 Jul 2023

COVID-19 vaccines saved lives of older adults with dementia in long-term care

Deaths among older adults with dementia fell starkly in nursing homes and long-term care centers after COVID-19 vaccinations became available, yet remained high for those living at home, according to a new study led by UC San Francisco.

17 Jul 2023

Griffith University researchers develop new method to control virus assembly

Griffith University researchers have played a key role in using DNA 'origami' templates to control the way viruses are assembled.

17 Jul 2023

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023