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Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Researchers at the Division of Infection and Immunity, University College London, UK, have provided key insights into the characteristics of the B.1.1.7 (or UK) variant of SARS-CoV-2.

24 Mar 2021

Long-term complications are common among COVID-19 recovered individuals

A team of scientists from the United Kingdom has recently conducted a multicenter, prospective cohort study to investigate long-term consequences of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Mar 2021

Researchers develop innovative biosensor that can detect and quantitate SARS-CoV-2 infection

Researchers have generated protease-activatable fluorescent and luminescent biosensors for SARS-CoV-2 MPro (main protease) and PLPro (papain-like protease) activity, one based on “flip” GFP (FlipGFP), and the other based on circularly permuted firefly luciferase (FFluc).

24 Mar 2021

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Being persistently lonely during midlife (ages 45-64) appears to make people more likely to develop dementia and Alzheimer's Disease (AD) later in life. However, people who recover from loneliness, appear to be less likely to suffer from dementia, compared to people who have never felt lonely.

24 Mar 2021

Cognitive decline is linked to COVID-19 lockdown, shows study

A decline in cognitive functions - such as memory, attention and decision-making - is connected to the tightest restrictions in Scotland's COVID-19 lockdown, a new peer-reviewed study has found.

24 Mar 2021

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

A new study adds to the sum of knowledge about SARS-CoV-2, with respect to its natural and biologically significant mutations, using computational modeling of the virus-receptor interactions. Understanding how viral mutations affect the virus-host interactions is crucial for shaping proper strategies to control the virus.

24 Mar 2021

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

24 Mar 2021

New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

A new study describes the use of a combination of virtual and experimental screening protocols to identify potential inhibitors of the virus, which could lead to rapid drug development.

24 Mar 2021

High throughput screening for COVID-19 with the VOYAGER pipette

The COVID-19 pandemic has slowed down research in many scientific areas, but for the Jain Lab in the Department of Chemical Engineering at the University of Florida, the pandemic has created an exciting opportunity to repurpose their work.

From INTEGRA Biosciences 24 Mar 2021

Living guidelines for stroke management can guide clinical practice, improve patient outcomes

Clear guidelines about effective rehabilitation techniques for leg and arm weakness after stroke have been introduced, providing greater direction for health professional and improved patient outcomes.

24 Mar 2021

New device set to revolutionize the resuscitation process for first responders

In response to the COVID-19 pandemic, performance manufacturer Keela Outdoors, NHS Tayside and Scottish Health Innovations (SHIL), have collaborated to design and develop a device that is set to revolutionize the resuscitation process for first responders.

24 Mar 2021

Survey of surge capacity managers captures pandemic preparedness status of the U.S. health care system

A University of Pittsburgh School of Medicine-led survey of dozens of surge capacity managers at hospitals nationwide captures the U.S. health care system's pandemic preparedness status in the months before the first COVID-19 cases were identified in China.

24 Mar 2021

Research reveals varied experiences of people involved in maternity care during COVID-19 pandemic

Doctors, midwives and midwifery students were more concerned about their exposure to COVID-19 while at work than the women receiving maternity care in the same settings, while the partners of those women reported feeling isolated because of changes to the way care was provided, new Curtin University research has found.

24 Mar 2021

Delaying second doses of COVID-19 vaccines can reduce positive cases

Delaying second doses of COVID-19 vaccines should reduce case numbers in the near term; however, the longer term case burden and the potential for evolution of viral ‘escape’ from immunity will depend on the robustness of immune responses generated by natural infections and one or two vaccine doses, according to a study from McGill University and Princeton University published today in Science.

24 Mar 2021

Telehealth consults accounted for 24% of outpatient consults with health care providers

A study co-authored by researchers at the Johns Hopkins Bloomberg School of Public Health found that telehealth consults among privately insured working-age patients accounted for almost 24 percent of outpatient consults with health care providers during the early phase of the pandemic, March to June 2020, up from less than 0.3 percent during the same period in 2019.

24 Mar 2021

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

A new preprint study led by Shawn S-C. Li from Western University in Ontario, Canada, provides evidence of epitope-specific antibody responses and designed a test to measure this in relation to disease severity and outcome after infection.

24 Mar 2021

Researchers develop “Crisis Standards of Care” policy to address ethical issues

During a public health crisis like the COVID-19 pandemic, U.S. hospitals need to allocate scarce medical resources in an equitable manner, according to clinicians and ethicists at the University of Miami Miller School of Medicine.

24 Mar 2021

New range of lung-on-chip technologies represent the vital properties of lung tissue

According to the National Institutes of Health, respiratory viruses are the most frequent cause of disease and death in humans, a fact highlighted by the COVID-19 pandemic. Despite the potential to cause severe disease, over 70% of viral infections remain asymptomatic.

24 Mar 2021

Study shows how surveillance-based informative testing mitigates COVID-19 spread

While COVID-19 cases may be on the decline, the virus is still prevalent nationwide, and higher education institutions need to prepare for a successful 2021 academic year.

24 Mar 2021

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients.

24 Mar 2021

covid 19 News and Research

Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Long-term complications are common among COVID-19 recovered individuals

Researchers develop innovative biosensor that can detect and quantitate SARS-CoV-2 infection

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Cognitive decline is linked to COVID-19 lockdown, shows study

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

High throughput screening for COVID-19 with the VOYAGER pipette

Living guidelines for stroke management can guide clinical practice, improve patient outcomes

New device set to revolutionize the resuscitation process for first responders

Survey of surge capacity managers captures pandemic preparedness status of the U.S. health care system

Research reveals varied experiences of people involved in maternity care during COVID-19 pandemic

Delaying second doses of COVID-19 vaccines can reduce positive cases

Telehealth consults accounted for 24% of outpatient consults with health care providers

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

Researchers develop “Crisis Standards of Care” policy to address ethical issues

New range of lung-on-chip technologies represent the vital properties of lung tissue

Study shows how surveillance-based informative testing mitigates COVID-19 spread

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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