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Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

A new study published in the journal Life Sciences has focused on examining the effects of ORF8 and ORF10 genes and SARS-CoV-2 Membrane (M) protein on apoptosis.

17 May 2022

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Researchers from Naval Medical University have been investigating anisodamine, used in traditional Chinese medicine, to inhibit SARS-CoV-2 infection in cellular models. The study is published in the journal Biochemical and Biophysical Research Communications.

17 May 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

Identifying new chemicals with greater effectiveness, safety than quisinostat

Announcing a new review article publication for Acta Materia Medica journal. In this article the authors use medicinal chemistry methods to identify new chemical entities with greater effectiveness and safety than quisinostat.

17 May 2022

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

Age-associated muscle decline can start as early as 40 years old and there are currently no effective interventions to counteract it other than exercise.

17 May 2022

As Red Cross moves to pricey blood treatment method, hospitals call for more choice

Americans generally don't spend much time thinking about the nation's blood supply.

17 May 2022

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Researchers from Ain Shams University have been exploring the use of compounds isolated from Aspergillus sp. against SARS-CoV-2.

13 May 2022

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

COVID-19-induced non-cell-autonomous anosmia

Researchers reported that SARS-CoV-2-induced anosmia was based on non-cell-independent processes.

11 May 2022

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more deadly.

10 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

Honeybee-based SARS-CoV-2 diagnostics

In a recent study posted to the Biology Open journal, researchers showed that honey bees could be conditioned to detect severe acute respiratory syndrome coronavirus (SARS-CoV-2)-infected samples.

6 May 2022

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism.

5 May 2022

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases.

4 May 2022

Novel surface coating protects implants and medical devices from infections

Infections after hip replacements and from orthopaedic device procedures can be complicated and lead to painful and repeat surgeries, with the chance of ‘superbugs’ leading to fatality.

4 May 2022

Uncovering a new molecule that shows potential as antidote for carbon monoxide poisoning

Carbon monoxide is an odorless and colorless gas made when fossil fuels burn incompletely. It's also a silent killer.

29 Apr 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

A cigarette smoke compound affects cartilage homeostasis

Cigarette smoke has been shown to deleteriously affect human health. For example, degenerative disc diseases are increasingly linked to cigarette smoking.

28 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Compound News and Research

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Experimental drug more effective than existing FDA-approved medications for ALS

Identifying new chemicals with greater effectiveness, safety than quisinostat

Study: Daily intake of Urolithin A improves muscle strength by 12% after four months

As Red Cross moves to pricey blood treatment method, hospitals call for more choice

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

COVID-19-induced non-cell-autonomous anosmia

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Tumors release lactate to force neighboring cells into supporting cancer growth

Honeybee-based SARS-CoV-2 diagnostics

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Novel surface coating protects implants and medical devices from infections

Uncovering a new molecule that shows potential as antidote for carbon monoxide poisoning

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

A cigarette smoke compound affects cartilage homeostasis

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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