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Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Long-COVID in adults and Ontario's expected burden

Scientists identify the healthcare requirements for adults with long COVID.

12 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Researchers assessed the association between Pfizer-BioNTech’s SARS-CoV-2 BNT162b2 messenger ribonucleic acid (mRNA) vaccination and the incidence of post-COVID-19 symptoms among Israeli adults.

12 Sep 2022

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

A new study aimed to analyze the epidemiological features of MPX, disease severity, as well as the impact of smallpox vaccination on all infected cases reported in the WHO European Region.

12 Sep 2022

The long-term clinical status of pediatric patients after testing positive for COVID-19

A recent study found that the most common long COVID symptoms in the pediatric population showed a higher prevalence among patients in the age range of 6-17 years and were identical to those reported in adults.

12 Sep 2022

The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

Scientists have conducted a systematic review and meta-analysis to evaluate the prevalence of neuropsychiatric manifestations associated with monkeypox infection.

12 Sep 2022

Minimally invasive procedure enables patients to be out of the hospital within a few days

Minimally invasive, catheter-based transcatheter aortic valve replacement (TAVR) has revolutionized treatment of aortic stenosis (AS), and both American and European guidelines have approved its use. However, there is a perception that TAVR is more expensive than surgical aortic valve replacement (SAVR). A budget impact analysis comparing the two options now shows that TAVR is an affordable and effective strategy for the treatment of AS. The study appears in the Canadian Journal of Cardiology, published by Elsevier.

12 Sep 2022

Pre-existing psychological distress increases risk of long-COVID

In a recent study published in the Journal of American Medical Association (JAMA) Psychiatry, researchers investigated the association of psychological distress before coronavirus disease 2019 (COVID-19) with the risk of post-acute sequelae of COVID-19 (PASC).

12 Sep 2022

New technology can capture stray ovarian cancer cells from a simple blood test

A new type of technology can capture stray ovarian cancer cells from a simple blood test and successfully predict cancer in people who have a lesion or cyst in the pelvic region, according to a new study by a Wilmot Cancer Institute physician/scientist.

9 Sep 2022

St. Baldrick's Scholar grant awarded to CU researcher for investigating new drug to treat infant leukemia

As part of its ongoing efforts to eradicate childhood cancers, the St. Baldrick's Foundation has awarded University of Colorado Cancer Center member Kelly Faulk, MD, a St. Baldrick's Scholar grant to investigate a new method for treating infant leukemia.

9 Sep 2022

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

John DeLuca, PhD, senior vice president of research and training at Kessler Foundation, received a five-year, $468,019 grant from the National Multiple Sclerosis Society to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program.

9 Sep 2022

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Monkeypox can sometimes lead to neurological complications such as encephalitis (brain inflammation), confusion or seizures, finds a new review of evidence led by a UCL researcher.

9 Sep 2022

Factors influencing patient’s perception during COVID-19 recovery

A team of researchers characterized individual-level illness perception, both cognitive and emotional, following COVID-19.

9 Sep 2022

Significantly enlarged gray matter volume in neuropsychiatric long-COVID syndrome

In a recent study published in the journal Psychiatry Research, researchers found larger gray matter volumes (GMVs) in patients with neuropsychiatric long COVID syndrome.

8 Sep 2022

Can preclinical COVID-19 models help unlock mystery of long-COVID?

In a recently published article in the journal PLOS PATHOGENS, scientists have summarized acute and prolonged clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The review also provides an overview of the potency and utility of preclinical animal models to understand the mechanistic details of acute and long coronavirus disease 2019 (COVID-19).

8 Sep 2022

Vaccines could help alleviate the symptoms of long COVID

Being vaccinated with at least two doses of Pfizer vaccines dramatically reduces most of the long-term symptoms individuals reported months after contracting COVID-19, a new study shows.

8 Sep 2022

Novel 3D-printed light-sensing medical device could help millions of lupus patients

A team of engineers and doctors at the University of Minnesota Twin Cities have designed a unique 3D-printed light-sensing medical device that is placed directly on the skin and gives real-time feedback to correlate light exposure with disease flare-ups.

8 Sep 2022

Donor iron deficiency produces no harmful effects on donated blood quality or donor wellbeing

Most of the U.S. blood supply comes from about 5 million altruistic volunteers who donate blood regularly. Frequent blood donation is known to result in iron deficiency in donors, which has led to concerns that the practice may not only diminish the quality of donated blood but also harm blood donors' health and quality of life.

8 Sep 2022

Psychological distress before COVID-19 infection associated with increased risk of long COVID

Psychological distress, including depression, anxiety, worry, perceived stress, and loneliness, before COVID-19 infection was associated with an increased risk of long COVID, according to researchers at Harvard T.H. Chan School of Public Health.

7 Sep 2022

Fatigue News and Research

Blocking FNDC5 prevents cancer-induced cachexia in mice

Long-COVID in adults and Ontario's expected burden

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

BNT162b2 SARS-CoV-2 vaccinations found to reduce incidence of long COVID symptoms

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

The long-term clinical status of pediatric patients after testing positive for COVID-19

The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

Minimally invasive procedure enables patients to be out of the hospital within a few days

Pre-existing psychological distress increases risk of long-COVID

New technology can capture stray ovarian cancer cells from a simple blood test

St. Baldrick's Scholar grant awarded to CU researcher for investigating new drug to treat infant leukemia

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Factors influencing patient’s perception during COVID-19 recovery

Significantly enlarged gray matter volume in neuropsychiatric long-COVID syndrome

Can preclinical COVID-19 models help unlock mystery of long-COVID?

Vaccines could help alleviate the symptoms of long COVID

Novel 3D-printed light-sensing medical device could help millions of lupus patients

Donor iron deficiency produces no harmful effects on donated blood quality or donor wellbeing

Psychological distress before COVID-19 infection associated with increased risk of long COVID

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