Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Researchers discover potential new therapeutic target for Ewing sarcoma

The sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, has identified a potential new therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents, and a tumor known by its aggressiveness and tendency to metastasize.

5 Apr 2018

New fluorescent probe identifies cancer stem cells

Cells with stem-cell characteristics appear to be especially important in the formation and metastasis of tumors. Scientists have now developed a universal fluorescent probe for these "cancer stem cells". As reported in the journal Angewandte Chemie, this dye also selectively kills off the cells.

4 Apr 2018

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

New insights into how cancer cells fuel their growth are opening novel possibilities for cancer treatment. A team of researchers at Baylor College of Medicine and Roswell Park Comprehensive Cancer Center has identified a long sought after connection between how cancer cells use the sugar glucose to generate energy - the Warburg pathway - and cancer growth.

3 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.

22 Mar 2018

Agendia receives CE mark for MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, today announces that its next-generation sequencing-based MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit is now CE marked, enabling the Company to commercialize the device in Europe.

22 Mar 2018

New DOD grant to support testing of promising therapy for triple-negative breast cancer

A unique cell surface protein found on triple-negative type breast cancer cells called JAG1 is a promising new therapeutic target for this hard-to-treat and highly metastatic type of breast cancer, according to researchers at the University of Illinois at Chicago.

21 Mar 2018

Scientists discover rare childhood liver cancer's ability to metastasize to the brain

A surprising finding by Rockefeller University scientists about a rare liver cancer's behavior could lead to more comprehensive patient monitoring and hopefully better outcomes.

19 Mar 2018

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

The International Journal of Cancer has just published the results of an experimental therapy tested on mice. The research, led by the Signaling Lab research group of the UPV/EHU's Faculty of Medicine and Pharmacy and the Department of Pharmacology, Pharmacy and Pharmaceutical Technology of the University of Santiago de Compostela, achieved an 80% reduction in liver metastasis brought about by colon cancer.

14 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

Breast cancer is the second leading cause of cancer death in women in the United States, with most deaths caused by the cancer spreading beyond the breast.

6 Mar 2018

NETRF awards six new research grants to improve treatments for neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today awarded six new research grants totaling $1.85 million to leading academic institutions around the world.

5 Mar 2018

Researchers use 3D jet writer to model metastatic cancer

Researchers have developed a 3D printer that uses polymers to generate a lifelike cancer microenvironment.

5 Mar 2018

Scientists move closer to developing alternative method for breast cancer detection

Engineering researchers at the University of Arkansas have moved closer to developing an alternative method of detecting and possibly treating breast cancer.

2 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Research reveals how mutant p53 enhances tumor metastasis

Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant.

26 Feb 2018

Metastasis News and Research

Further Reading

Researchers discover potential new therapeutic target for Ewing sarcoma

New fluorescent probe identifies cancer stem cells

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

Agendia receives CE mark for MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit

New DOD grant to support testing of promising therapy for triple-negative breast cancer

Scientists discover rare childhood liver cancer's ability to metastasize to the brain

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

NETRF awards six new research grants to improve treatments for neuroendocrine tumors

Researchers use 3D jet writer to model metastatic cancer

Scientists move closer to developing alternative method for breast cancer detection

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Research reveals how mutant p53 enhances tumor metastasis

Repurposing leukemia drugs may be effective approach for treating metastatic melanoma patients

UC Riverside researchers discover way to halt cancer metastasis

Rare immune cell may prove to be potent weapon in fighting against cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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