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Study suggests fermentation as a sustainable and easily applicable biotechnology to overcome the legume flour technological and sensory drawbacks

Researchers used Mediterranean black chickpea flour in the form of a semi-liquid dough fermented with the bacteria Lactiplantibacillus plantarum to develop fortified semolina pasta with improved nutritional quality.

24 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

New prototype treatment proves effective against the venom of African and Asian elapid snakes

Prototype treatment for snake bite envenoming proves effective against the venom of African and Asian elapid snakes, such as some cobra, mamba, and krait species, new research shows.

23 Feb 2023

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Changing dietary fiber structure promotes healthy gut bacteria and reduces gas formation

Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.

16 Feb 2023

An oral and on-demand male contraceptive

Researchers identify a soluble adenylyl cyclase (sAC) inhibitor that has the potential to be used as an on-demand oral contraceptive for men.

16 Feb 2023

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Inventia Life Science, a world leader in advanced cell models for biomedical research and drug discovery, today announced a collaboration with MSD (tradename of Merck & Co., Inc., Rahway, N.J., USA) using Inventia’s RASTRUM™ 3D cell culture platform.

From Inventia Life Science 16 Feb 2023

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Researchers examine non-hospitalized adult patients with COVID-19 treated with nirmatrelvir-ritonavir.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Scientists reach a substantial consensus on the four principles that will enable the future development and expansion of virus taxonomy

A team of 45 virologists, evolutionary biologists, bioinformaticians, and structural biologists from around the world arrived at a consensus on virus classification methodologies and presented an integrated taxonomical framework for the systematics and taxonomy of viruses.

15 Feb 2023

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Scientists report that the active compound from an edible mushroom, Hericium erinaceus, can enhance nerve growth and boost memory.

13 Feb 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils.

13 Feb 2023

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies - in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient - are changing the prospects of cancer patients.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

in vitro News and Research

Study suggests fermentation as a sustainable and easily applicable biotechnology to overcome the legume flour technological and sensory drawbacks

NQO2 gene as a novel potential target in Parkinson’s disease

New prototype treatment proves effective against the venom of African and Asian elapid snakes

Novel fatty liver organoid models could aid in drug discovery and testing

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Step-by-step process of rewiring cells to generate germ cell precursors

First fully human ovarian organoids provide insights about female reproductive health and disease

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Changing dietary fiber structure promotes healthy gut bacteria and reduces gas formation

An oral and on-demand male contraceptive

Inventia Life Science collaborates with MSD to develop 3D advanced cell models for neurodegenerative disease drug discovery

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Scientists reach a substantial consensus on the four principles that will enable the future development and expansion of virus taxonomy

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Casein-based diet found to protect diabetic mice against autoimmunity

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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