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Key to treat deadly cancers could lie deep within complex machinery of human cell

Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University.

27 Feb 2019

Study shows connection between maternal smoking during pregnancy and offspring ADHD

The higher the cotinine levels were in the mother's blood during pregnancy, the greater was the child's risk of developing attention deficit hyperactivity disorder later in life, showed an epidemiological study conducted by the Research Centre for Child Psychiatry at the University of Turku in Finland.

26 Feb 2019

Study: Chikungunya virus arrived in Brazil at least one year before it was detected

New evidence suggests that Chikungunya virus arrived in Brazil at least one year earlier than it was detected by public health surveillance systems.

26 Feb 2019

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.

26 Feb 2019

'Chromosome scanner' that protects against cancer identified

In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A 'scanner' inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched.

26 Feb 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Researchers pinpoint a set of enzymes involved in colon cancer growth

University of Massachusetts Amherst food science researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer.

26 Feb 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields.

25 Feb 2019

Specific gene variation associated with ADHD could be tied to substance addiction

Some variations in the gene LPHN3 -associated with the attention deficit/hyperactivity disorder (ADHD) in kids and adults- could favor likelihood to smoke, consume alcohol, cannabis and other addictive substances, according to an article published in the journal Translational Psychiatry, from the Nature Publishing Group.

25 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Study provides vital clues to why some people have higher COPD risk than others

A group of researchers led by the Universities of Leicester and Nottingham has discovered genetic differences that put some people at higher risk than others of developing chronic lung disease.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Obesity and severe obesity added as risk factors for premature heart disease in children

Obesity and severe obesity in childhood and adolescence have been added to the list of conditions that put children and teens at increased risk for premature heart disease, according to a new scientific statement from the American Heart Association published in the Association's journal Circulation.

25 Feb 2019

Using CRISPR to regulate genes in the rat brain

Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Described in eNeuro, this technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that more closely resemble human conditions.

From Society for Neuroscience 25 Feb 2019

Neuron-derived estrogen key to making memories

Estrogen in the brain is important to keep neurons communicating and memories being made, scientists report.

25 Feb 2019

New form of hereditary osteoporosis identified

A research group headed by Professor Outi Mäkitie, Unviersity of Helsinki, identified in families with childhood-onset osteoporosis disease-causing mutations in a gene that had previously not been connected with the skeletal system or osteoporosis.

25 Feb 2019

Paying more attention to antibiotic dosing could improve clinical outcomes for CF patients

Children and young adults with cystic fibrosis (CF) whose lung infections were treated with suboptimal doses of antibiotics had fewer changes in lung microbial diversity during the IV treatment, and their microbial diversity levels were higher 30 days later, a multi-institutional study that includes Children's researchers shows.

23 Feb 2019

Older biologic age associated with increased risk of developing breast cancer

Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health.

23 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Genetic News and Research

Key to treat deadly cancers could lie deep within complex machinery of human cell

Study shows connection between maternal smoking during pregnancy and offspring ADHD

Study: Chikungunya virus arrived in Brazil at least one year before it was detected

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

'Chromosome scanner' that protects against cancer identified

Scientists report new and improved method to detect chemical modifications to DNA

Researchers pinpoint a set of enzymes involved in colon cancer growth

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

Specific gene variation associated with ADHD could be tied to substance addiction

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Study provides vital clues to why some people have higher COPD risk than others

Scientists identify cause of devastating pediatric brain disorder

Obesity and severe obesity added as risk factors for premature heart disease in children

Using CRISPR to regulate genes in the rat brain

Neuron-derived estrogen key to making memories

New form of hereditary osteoporosis identified

Paying more attention to antibiotic dosing could improve clinical outcomes for CF patients

Older biologic age associated with increased risk of developing breast cancer

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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