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EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Despite the fact that the incidence of cancer is many fold higher in persons over 65 years of age, we still have an inadequate understanding on how best to treat these older cancer patients. Furthermore, even though elderly patients are occasionally included in clinical trials, those elderly patients who are eventually included are mostly 'healthy' (fit) elderly patients.

20 Jun 2013

Researchers develop method to identify aggressive prostate cancers

Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.

20 Jun 2013

Stress exposure may be associated with increased risk of aggressive breast cancer

Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research.

19 Jun 2013

New chemical probe confirms that hydrogen sulfide is generated by body's growing cells.

A new study confirms directly what scientists previously knew only indirectly: The poisonous "rotten egg" gas hydrogen sulfide is generated by our body's growing cells.

19 Jun 2013

New blood test finds cancer-related microRNA in blood before tumor development

A new blood test developed in the Gastrointestinal Cancer Research Lab at Baylor Research Institute is showing very promising results for finding cancer-related microRNA in the blood before a tumor develops in the colon.

19 Jun 2013

Smoking before surgery can lead to morbidity and complications for neurosurgical procedures

The effects of long-term cigarette smoking on morbidity and mortality have long been known. In a more immediate sense, smoking in the days and weeks before surgery can lead to morbidity and complications for many surgical procedures.

19 Jun 2013

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.

19 Jun 2013

Aspirin slows accumulation of DNA mutations in abnormal cells, points UCSF scientist

Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition.

19 Jun 2013

Researchers identify biochemical pathway essential for promoting head and neck cancer

A study led by researchers at The Ohio State University Comprehensive Cancer Center-- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a biochemical pathway in cancer stem cells that is essential for promoting head and neck cancer.

19 Jun 2013

UCSC experts awarded $3.5M NIH grant to develop cancer genomics tools

Despite some successes, predicting cancer outcomes based on the molecular signatures in cancer cells remains a major challenge. A new effort, funded by the National Cancer Institute and led by researchers at the University of California, Santa Cruz, aims to clear several key roadblocks that have stymied progress in this field.

18 Jun 2013

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumor cancers, announced the completion of patient enrollment in a Phase II clinical trial of ImmunoPulse for metastatic melanoma patients.

18 Jun 2013

Moffitt Cancer Center, Advinus Therapeutics form strategic partnership

Moffitt Cancer Center announced a strategic partnership with Advinus Therapeutics to advance its discoveries to the clinics. Two promising targeted cancer therapies (Rb:Raf-1 disruptor and ROCK inhibitor) developed by Moffitt scientists are selected as the first set.

18 Jun 2013

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

18 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.

18 Jun 2013

RetroNectin reagent now available for gene therapy clinical research

In an effort to aid progress in gene therapy clinical research, representatives of Clontech laboratories, Inc. and its parent company Takara Bio Inc. announce the availability of clinical grade RetroNectin reagent for direct supply to biomedical researchers.

17 Jun 2013

Mount Sinai researchers present several new studies at ENDO 2013

Researchers from the Icahn School of Medicine at Mount Sinai will present several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo from June 15-18 in San Francisco.

17 Jun 2013

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

A mechanism that cells use to group together and move around the body - called 'chase and run' - has been described for the first time by scientists at UCL.

17 Jun 2013

Dosimetry based on 3-D medical images estimates possible dose for targeted RIT in blood cancer patients

Outcomes can be bleak for non-Hodgkin lymphoma (NHL), a cancer that develops in the white blood cells of the immune system. Accurate estimation of radiation absorbed dose in radioimmunotherapy (RIT) based on state-of-the-art 3D imaging could lead to more personalized and effective treatments to improve patients' chances of living longer without progression of their cancer, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

15 Jun 2013

UCSF researchers discover memory-boosting molecule in mice

Memory improved in mice injected with a small, drug-like molecule discovered by UCSF San Francisco researchers studying how cells respond to biological stress.

15 Jun 2013

Tumor News and Research

EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Researchers develop method to identify aggressive prostate cancers

Stress exposure may be associated with increased risk of aggressive breast cancer

New chemical probe confirms that hydrogen sulfide is generated by body's growing cells.

New blood test finds cancer-related microRNA in blood before tumor development

Smoking before surgery can lead to morbidity and complications for neurosurgical procedures

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Aspirin slows accumulation of DNA mutations in abnormal cells, points UCSF scientist

Researchers identify biochemical pathway essential for promoting head and neck cancer

UCSC experts awarded $3.5M NIH grant to develop cancer genomics tools

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

Moffitt Cancer Center, Advinus Therapeutics form strategic partnership

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

RetroNectin reagent now available for gene therapy clinical research

Mount Sinai researchers present several new studies at ENDO 2013

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

Dosimetry based on 3-D medical images estimates possible dose for targeted RIT in blood cancer patients

UCSF researchers discover memory-boosting molecule in mice

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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