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Brain protein mutation from an autistic person alters behavior in mice

A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

24 Jul 2019

Tailored adherence strategies needed to engage young African women in consistent PrEP use

In a study of open-label Truvada as daily pre-exposure prophylaxis (PrEP) to prevent HIV among 427 young African women and adolescent girls, 95% initiated the HIV prevention strategy, and most used PrEP for the first three months.

24 Jul 2019

Women who inherit BRCA mutations have high risk of developing cancer

Women who inherit harmful mutations in the BRCA1 or BRCA2 gene are at high risk of developing breast and ovarian cancer.

24 Jul 2019

People experienced more cardiovascular events when unable to obtain their LDL-cholesterol drug

Individuals at high risk for cardiovascular events, including those with familial hypercholesterolemia or atherosclerotic heart disease experienced more heart attacks, strokes and other cardiovascular events when they were unable to obtain their prescribed LDL-cholesterol lowering medication.

24 Jul 2019

E. coli superbug can live in women’s gut without symptoms

Virulent and multi-drug resistant strains of Escherichia coli can thrive in women’s gut even without any symptoms, a new study found.

23 Jul 2019

Federal suit alleges ‘staggering’ urine drug testing fraud at Tennessee pain clinics

The Justice Department on Monday accused a defunct chain of Tennessee-based pain clinics of cheating Medicare and other taxpayer-funded health insurers out of at least $25 million in needless urine drug tests and genetic testing.

23 Jul 2019

Researchers design nanodrone to detect toxic gases in emergencies

Detecting dangerous gases in collapsed buildings due earthquakes or explosions and identifying the presence of victims in places which are hard to access are some action scenarios of SNAV, a nanodrone designed and created by the researchers Santiago Marco and Javier Burgués, from the Faculty of Physics of the University of Barcelona and the Institute for Bioengineering of Catalonia.

23 Jul 2019

Patients have higher risk of heart problems when insurance companies reject their prescriptions

Patients appear to be at higher risk of heart problems or stroke when prescriptions for the newest cholesterol-lowering drugs are rejected by insurance companies or unfilled by patients, according to new research in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

23 Jul 2019

Research shows how freshwater prawns could reduce schistosomiasis transmission

Before bite-sized crustaceans like crayfish, shrimp and prawns land on our dinner plates, they first have to get fat themselves -- and it turns out they relish the freshwater snails that transmit the parasite that causes schistosomiasis, the second most devastating parasitic disease worldwide, after malaria.

23 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Scientists use AI to improve diagnosis and monitoring of rare eye condition

Fight for Sight is funding research by scientists from universities and hospitals in Birmingham and London using artificial intelligence to extract ‘hidden’ information from retinal images of patients with a rare eye condition called birdshot uveitis.

23 Jul 2019

Recreational drugs more likely to be tried for the first time in summer, study shows

American teenagers and adults are more likely to try illegal or recreational drugs for the first time in the summer, a new study shows.

23 Jul 2019

Obstructive sleep apnea may be one reason for treatment-resistant depression

When someone is depressed and having suicidal thoughts or their depression treatment just isn't working, their caregivers might want to check to see if they have obstructive sleep apnea, investigators say.

23 Jul 2019

Women with breast cancer should start postoperative chemotherapy soon

Women with breast cancer should start postoperative chemotherapy, when recommended, ideally within four months of their cancer diagnosis because new study findings show that waiting longer is associated with poorer overall survival.

23 Jul 2019

High-resolution images offer clues to improve design of anti-nausea drugs

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

23 Jul 2019

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

23 Jul 2019

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

Continuation of community-wide HIV testing and prompt initiation of treatment as delivered in the HPTN 071 study in South Africa and Zambia could lead to substantial reductions in new HIV cases, be cost-effective, and help to achieve the UNAIDS 2030 targets, according to projections from mathematical modeling and cost-effectiveness analyses presented today at the 10th International AIDS Society Conference on HIV Science in Mexico City.

23 Jul 2019

Scientists identify new way to target bottleneck for cancer cell growth

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.

23 Jul 2019

Online pain and mood symptom self-management works better when coupled with clinician telecare

Pain is the most common physical symptom for which adults seek medical attention in the United States, while anxiety and depression are the most common mental health symptoms for which adults visit a doctor. Drugs, especially opioids, may not be the only or best therapy.

22 Jul 2019

FDA grants approval for generic versions of Lyrica

On July 19, the U.S. Food and Drug Administration approved multiple applications for first generics of Lyrica (pregabalin) for the management of neuropathic pain associated with diabetic peripheral neuropathy, for the management of postherpetic neuralgia, as an adjunctive therapy for the treatment of partial onset seizures in patients 17 years of age and older, for the management of fibromyalgia, and for the management of neuropathic pain associated with spinal cord injury.

22 Jul 2019

Drugs News and Research

Brain protein mutation from an autistic person alters behavior in mice

Tailored adherence strategies needed to engage young African women in consistent PrEP use

Women who inherit BRCA mutations have high risk of developing cancer

People experienced more cardiovascular events when unable to obtain their LDL-cholesterol drug

E. coli superbug can live in women’s gut without symptoms

Federal suit alleges ‘staggering’ urine drug testing fraud at Tennessee pain clinics

Researchers design nanodrone to detect toxic gases in emergencies

Patients have higher risk of heart problems when insurance companies reject their prescriptions

Research shows how freshwater prawns could reduce schistosomiasis transmission

Unexpected discovery could improve treatment of cancer, other diseases

Scientists use AI to improve diagnosis and monitoring of rare eye condition

Recreational drugs more likely to be tried for the first time in summer, study shows

Obstructive sleep apnea may be one reason for treatment-resistant depression

Women with breast cancer should start postoperative chemotherapy soon

High-resolution images offer clues to improve design of anti-nausea drugs

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

Scientists identify new way to target bottleneck for cancer cell growth

Online pain and mood symptom self-management works better when coupled with clinician telecare

FDA grants approval for generic versions of Lyrica

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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