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New NIH funding will accelerate progress in TB vaccine development

Seattle Children's Research Institute is one of three recipients of $30 million in first-year-funding provided by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to establish centers for immunology research to accelerate progress in tuberculosis vaccine development.

15 Nov 2019

White House unveils finalized health care price transparency rule

Hospitals will soon have to share price information they have long kept obscured — including how big a discount they offer cash-paying patients and rates negotiated with insurers — under a rule finalized Friday by the Trump administration.

15 Nov 2019

Older Mexican Americans experiencing pain more likely to become frail, study shows

Researchers funded by the National Institutes of Health have found that older Mexican Americans who suffer from pain were 1.7 times likelier to become frail, compared to study participants who did not report pain.

15 Nov 2019

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease.

15 Nov 2019

HIV-exposed but uninfected individuals at risk of obesity and asthma-like symptoms

Adolescents and young adults who were born to mothers with HIV but remained uninfected themselves still face a greatly heightened risk of obesity and asthma-like symptoms, researchers from Massachusetts General Hospital have found.

15 Nov 2019

Virtual cardiology follow-ups are a feasible alternative for pediatric cardiac conditions

Health provider follow-ups delivered via computer or smartphone is a feasible alternative to in-person patient follow-ups for some pediatric cardiac conditions, according to the findings of a pilot study presented at the AHA Scientific Sessions this week.

15 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

Four important tips to stay safe and healthy during winter

Colder temperatures, inclement weather, changes in the amount of daylight, and the spread of cold and flu viruses can all have a significant impact on your winter well-being, making it more challenging for you to stay safe and healthy.

15 Nov 2019

New study aims to optimize brain development in babies with congenital heart disease

An upcoming clinical trial at Children's National Hospital will harness cardiopulmonary bypass as a delivery mechanism for a novel intervention designed to stimulate brain growth and repair in children who undergo cardiac surgery for congenital heart disease.

14 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Improved method for predicting retinopathy of prematurity could reduce unnecessary tests

A multicenter group of 41 hospitals led by researchers at Children's Hospital of Philadelphia (CHOP) has confirmed that an improved method for predicting retinopathy of prematurity (ROP), a leading cause of blindness in children, was able to reduce the number of babies having invasive diagnostic examinations by nearly a third, while raising disease detection up to 100 percent.

14 Nov 2019

KHN’s ‘What the Health’: Spending bill slowdown

The fiscal year started a month and a half ago, but Congress has still not agreed on an annual spending bill for the Department of Health and Human Services - or any of the other annual spending bills that fund the government.

14 Nov 2019

Added sugar in 60 percent of infant, toddler foods

How young do you have to be to escape the lure of unhealthy foods? It’s never too young, finds a new study published in the Journal of the Academy of Nutrition and Dietetics on November 14, 2019.

14 Nov 2019

Lithium corrects radiation damage to brain in young cancer patients

A new study on mice, published online in the journal Molecular Psychiatry, on November 14, 2019, shows that the intermittent use of lithium, which is widely used to stabilize the mood in conditions such as bipolar disorder, can correct memory and learning losses due to radiation therapy to the brain in very young animals, even when the lithium is given long after the injury.

14 Nov 2019

Study sheds light on how Zika virus causes microcephaly in newborns

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons.

14 Nov 2019

Fluctuating weight changes can repeat in second pregnancy and can predict poor outcomes

Everyone knows that gaining excess weight during one pregnancy is bad, but clinicians rarely consider weight gains and losses from one pregnancy to the next--especially in normal-weight women.

14 Nov 2019

Study supports positive associations with mother-child bonding experiences during and after pregnancy

A study in the Journal of the American Academy of Child and Adolescent Psychiatry, published by Elsevier, reports that home-visiting by trained community workers during and after pregnancy can improve mother-child interactions in the first years of life.

14 Nov 2019

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

AstraZeneca and MSD (Merck) announced today that the U.S. Food and Drug Administration (FDA) has granted acceptance to file status of its application for the MEK inhibitor selumetinib, for use in patients with plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

14 Nov 2019

Bisphenol-s and bisphenol-f may have less impact on heart function than bisphenol-a

Some chemical alternatives to plastic bisphenol-a (BPA), which is still commonly used in medical settings such as operating rooms and intensive care units, may be less disruptive to heart electrical function than BPA, according to a pre-clinical study that explored how the structural analogues bisphenol-s (BPS) and bisphenol-f (BPF) interact with the chemical and electrical functions of heart cells.

14 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Children News and Research

New NIH funding will accelerate progress in TB vaccine development

White House unveils finalized health care price transparency rule

Older Mexican Americans experiencing pain more likely to become frail, study shows

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

HIV-exposed but uninfected individuals at risk of obesity and asthma-like symptoms

Virtual cardiology follow-ups are a feasible alternative for pediatric cardiac conditions

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Four important tips to stay safe and healthy during winter

New study aims to optimize brain development in babies with congenital heart disease

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Improved method for predicting retinopathy of prematurity could reduce unnecessary tests

KHN’s ‘What the Health’: Spending bill slowdown

Added sugar in 60 percent of infant, toddler foods

Lithium corrects radiation damage to brain in young cancer patients

Study sheds light on how Zika virus causes microcephaly in newborns

Fluctuating weight changes can repeat in second pregnancy and can predict poor outcomes

Study supports positive associations with mother-child bonding experiences during and after pregnancy

FDA grants acceptance to application for selumetinib as treatment for neurofibromatosis

Bisphenol-s and bisphenol-f may have less impact on heart function than bisphenol-a

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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