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Researchers identify toxin responsible for Legionella growth

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells.

22 Jul 2019

People successfully treated for visceral leishmaniasis can still infect others, study confirms

The results of an innovative "infectivity" study conducted by the Drugs for Neglected Diseases initiative and the International Centre for Diarrhoeal Disease Research, Bangladesh confirm that people successfully treated for visceral leishmaniasis in South Asia can still infect others if they develop a skin condition known as post-kala-azar dermal leishmaniasis.

22 Jul 2019

Researchers identify encephalitis as rare toxicity of immunotherapy treatment

After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center investigated why the complication occurred, performing a molecular analysis of the disease's pathology and mining data to determine the incidence of similar occurrences.

22 Jul 2019

Researchers identify new mechanism for deactivation of switch proteins

A new mechanism for the deactivation of switch proteins has been identified by researchers from Ruhr-Universität Bochum, headed by Professor Klaus Gerwert and Dr. Till Rudack from the Department of Biophysics, and the University of Uppsala in Sweden.

22 Jul 2019

IAS 2019 spotlights challenge of providing HIV services in humanitarian crises

More than 5,000 people from 140 counties have gathered in Mexico City for the opening of the 10th IAS Conference on HIV Science, where global experts called for urgent action to address the health needs of millions of people affected by humanitarian crises.

22 Jul 2019

Researchers publish review on serial femtosecond crystallography

Researchers from the Moscow Institute of Physics and Technology have published a review on serial femtosecond crystallography, one of the most promising methods for analyzing the tertiary structure of proteins.

22 Jul 2019

New EU-funded project helping to develop safer, more effective medicines

Chiral pharmaceuticals are widely used in clinical treatments and agriculture. They include non-steroid anti-inflammatory drugs, Î²-blockers for reducing blood pressure, and herbicides and pesticides.

22 Jul 2019

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions.

22 Jul 2019

Understanding how anti-malarial drug primaquine works lead to more effective malarial therapies

Researchers at LSTM have taken significant steps in understanding the way that the anti-malarial drug primaquine works, which they hope will lead to the development of new, safer and more effective treatments for malaria.

22 Jul 2019

New organic molecule could become potent weapon in the fight against antibiotic resistance

An organic molecule composed of simple sugars could become a potent weapon in the fight against rising antibiotic resistance, according to EU-funded researchers who have developed a novel, targeted drug-delivery technique to treat deadly tuberculosis and other lethal pathogens.

21 Jul 2019

Non-invasive diagnostic method could aid in early detection, monitoring of bladder cancer

This non-invasive diagnostic method could help detect the disease in its earliest stages with a small urine sample.

19 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

Research reveals how mirror therapy relieves phantom limb pain

Easing phantom limb pain can be as simple as looking in the mirror. Scientists who have mapped how mirror therapy changes the brain may now be able to predict just how much treatment will ease a particular patient’s pain.

19 Jul 2019

NHS England pilot paves way for new smartphone-based UTI test

WOMEN who suspect they have a urinary tract infection will be able to access fast-track testing and treatment — without seeing a GP — as part of a ground-breaking NHS England pilot scheme being trialed in 38 ‘Pharmacy First’ branches across Nottinghamshire and Derbyshire.

19 Jul 2019

Some pharmacists not adhering to therapeutic guidelines, QUT study finds

As the role of pharmacies in providing front-line public health services grows, a QUT study has raised concerns that some are not adhering to therapeutic guidelines when distributing pharmaceuticals.

19 Jul 2019

Some pharmacists fail to adhere to therapeutic guidelines, highlights study

As the role of pharmacies in providing front-line public health services grows, a QUT study has raised concerns that some are not adhering to therapeutic guidelines when distributing pharmaceuticals.

19 Jul 2019

KHN’s ‘What the Health?’: Biden doubles down on Obamacare

Former Vice President Joe Biden has said if he's elected president he would build on the Affordable Care Act rather than move to a whole new health care system, such as the "Medicare for All" plan supported by some of his primary opponents for the Democratic nomination.

19 Jul 2019

Chemotherapy drugs delivered using biodegradable paste can prolong survival in brain cancer

A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered.

18 Jul 2019

New research links “broken heart syndrome” to cancer

Researchers have discovered a new link between broken-heart syndrome, or takotsubo syndrome, and the second leading cause of death in the world: cancer.

18 Jul 2019

Study defines how diarrhea-causing rotavirus initially interacts with the host

Research by the Department of Microbiology of the University of Valencia, the Institute of Biomedicine of Valencia and the Institute of Agrochemistry and Food Technology of the CSIC has defined the initial interaction of human rotavirus P [8] (the main cause of gastroenteritis) with the recipients of the intestine.

18 Jul 2019