Genetic News and Research

RSS

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

Researchers identify why heart attack triggers arrhythmia in some people

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

29 Jan 2019

RNA-induced gene fusion can occur in mammalian cells, reveals study

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome.

29 Jan 2019

Research provides new understanding of genome regulation in early life

After the fertilization of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilization, what kick starts the interpretation of these instructions?

29 Jan 2019

Researchers develop powerful new tool to create concrete cortical blueprint

With a bit of light, a few photo sensitive compounds and specialized paper, the blueprint was born. As the favored type of technical drawing for over a century, architects used this crucial tool for its fast reproducibility as well as its capacity for detailed documentation.

29 Jan 2019

EZH2 mutations can be used as marker for diagnosing different types of cancers

Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call "chromatin".

29 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Genetic testing to be provided by the NHS in exchange for genomic data

The NHS is going to start providing genetic tests in exchange for patients in England who agree to share their genomic data so that it can be used for research.

28 Jan 2019

Study identifies new genetic variant associated with ARDS

An international study in which Javier Belda, Professor of Surgery at the University of Valencia and Incliva researcher, participated, has identified a new genetic variant associated with Acute Respiratory Distress Syndrome.

28 Jan 2019

Researchers discover immune regulator that appears to dictate glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance, indicating a potential new area of therapeutic investigation.

28 Jan 2019

Gluten-free wheat can be produced for people with celiac disease by using gene editing

One to two per cent of the population has Celiac Disease (CD), an immune reaction to gluten. Wheat grains contain gluten, a mixture of glutenin and gliadin proteins, which build a network that gives wheat bread its unique properties and quality.

28 Jan 2019

Study: Prolonged presence of precursor cells in thymus may give rise to leukemia

Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. This blood cancer appears from the precursor cells that produce T lymphocytes.

28 Jan 2019

Study finds that spatial architecture largely dictates connectivity within the brain

A University of California, Irvine-led study reveals that connectivity within the brain appears to be largely dictated by spatial architecture rather than cell type-specific cues. The study was published this month in Cell Reports.

27 Jan 2019

Association between tobacco use and paranoia is largely due to shared genetic influences

Paranoia is associated with regular tobacco smoking in adolescents after accounting for other factors like cannabis use, sleep disturbances and stressful life events, reports a study recently published to the Journal of the American Academy of Child and Adolescent Psychiatry.

25 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

Copy number variants linked with 'schizophrenia-like' subtype of bipolar disorder

A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder.

25 Jan 2019

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Discovery could guide future treatments for patients with hypertension

A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran's Affairs, has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension.

25 Jan 2019

Genetic risk for developing psychiatric disorders or cognitive traits manifest in brain structure from childhood

There is only scant scientific evidence available on whether the genetic risk for developing specific psychiatric disorders or cognitive traits is manifest in brain structure from childhood and, to date, studies have focused primarily on adult populations. The question remains unanswered.

25 Jan 2019

Identical twins shine new light on genetic cause of juvenile arthritis

Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease.

24 Jan 2019

Genetic News and Research

Big data opens door for characterizing immunity-related genome in Japanese population

Researchers identify why heart attack triggers arrhythmia in some people

RNA-induced gene fusion can occur in mammalian cells, reveals study

Research provides new understanding of genome regulation in early life

Researchers develop powerful new tool to create concrete cortical blueprint

EZH2 mutations can be used as marker for diagnosing different types of cancers

New class of antisense oligonucleotide therapeutics tested in humans

Genetic testing to be provided by the NHS in exchange for genomic data

Study identifies new genetic variant associated with ARDS

Researchers discover immune regulator that appears to dictate glioblastoma

Gluten-free wheat can be produced for people with celiac disease by using gene editing

Study: Prolonged presence of precursor cells in thymus may give rise to leukemia

Study finds that spatial architecture largely dictates connectivity within the brain

Association between tobacco use and paranoia is largely due to shared genetic influences

Scientists pinpoint mechanism that leads to steroid diabetes

Copy number variants linked with 'schizophrenia-like' subtype of bipolar disorder

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Discovery could guide future treatments for patients with hypertension

Genetic risk for developing psychiatric disorders or cognitive traits manifest in brain structure from childhood

Identical twins shine new light on genetic cause of juvenile arthritis

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News