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New study finds that previously described differences among endoscopists are not true

Previous research has suggested that specific factors about the doctor performing colonoscopy - for example, a gastroenterologist versus a surgeon, female versus male - were associated with different rates of detection of precancerous polyps.

19 Apr 2019

New technology developed for microscopic imaging in living organisms

Biotechnologists, physicists, and medical researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have developed technology for microscopic imaging in living organisms.

17 Apr 2019

Restoring function of 'misregulated' cancer-fighting genes

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the function of hundreds of cancer-fighting genes that became "misregulated" by the disease.

15 Apr 2019

Cancer cells use tactics to avoid being recognised by immunotherapy agents

Researchers have found that bowel cancer cells have a mechanism by which they can switch off some key molecules on their surfaces and thus escape being recognised and killed by the immunotherapy agents.

15 Apr 2019

Johns Hopkins scientists design new cell model of aging-associated colon cancer risk

Johns Hopkins Kimmel Cancer Center researchers say a new study of clusters of mouse cells known as "organoids" has significantly strengthened evidence that epigenetic changes, common to aging, play a essential role in colon cancer initiation.

12 Apr 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

Eight-year study identifies potential new way to treat extreme childhood food allergy

An eight-year hunt for the cells that drive the extreme childhood food allergy eosinophilic esophagitis has identified a potential new way to treat the disease while also raising questions about a dietary supplement often taken to reduce bowel inflammation.

9 Apr 2019

Blood-based test for colon cancer shows promise, study finds

If caught early, nearly all cases of colon cancer are curable. Though this should make screening tests straightforward, colon cancer screening suffers from a paradoxical combination of low compliance rates and overdiagnosis.

9 Apr 2019

U.K. guidelines for tests drastically differ from those in the U.S, reports Sah

Dr. Sunita Sah practiced general medicine for several years in the United Kingdom's National Health Service. When she came to the United States, she noticed something strange.

8 Apr 2019

Gene levels could be good indicator of prognosis in colorectal cancer patients

Levels of a gene that helps the immune system differentiate the good cells from the bad could be a good indicator of prognosis in people with colorectal cancers, Medical College of Georgia researchers report.

3 Apr 2019

Compounds derived from common hop plant thwart cancer cells

The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

3 Apr 2019

UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

After 10 years in remission, Derek Ruff's cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed.

2 Apr 2019

Colorecal cancer commonly misdiagnosed in patients under 50

A recent survey has found that a significant number of patients who develop colorectal cancer (CRC) before the age of 50 are misdiagnosed several times.

1 Apr 2019

Fish slime could be a potential source of antibiotics finds study

With the advent of multi-drug resistant bacteria and lack of new antibiotics, researchers have been on the lookout for new molecules that can fight these pathogens. A team of researchers have now identified a slimy mucous coating of young fish as a potential source for antibiotics that could fight resistant infections such as MRSA (Methicillin Resistant Staphylococcus aureus).

31 Mar 2019